Abstract
Release of airborne mutagens associated with inhalable particles may occur in various industrial, governmental, and public activities. These activities include transportation, manufacturing, mining, refining, processing of materials, agricultural procedures, electric power generation, and other processes involving combustion and vaporization. People may be exposed to mutagenic aerosols in occupational exposure to process or fugitive emissions, or during use of aerosolizable or volatile mutagenic materials. The general public may be exposed to environmental concentrations (released airborne materials) or in the course of using various product materials or other personal activities.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
O. G. Raabe, Generation and Characterization of Aerosols, in: “Inhalation Carcinogenesis,” M. G. Hanna, Jr., P. Nettesheim and J. R. Gilbert, eds., U.S. Atomic Energy Commission, Oak Ridge, TN, 123–172 (1970).
A. R. McFarland, R. W. Bertsch, G. L. Fisher , B. A. Prentice, A fractionator for size-classification of aerosalized solid particulate matter. Environ. Sci. Technol. 11:781–784 (1977).
D. F. S. Natusch, J. R. Wallace, C. A. Evans, Jr., Toxic trace elements: a perferential concentration in respirable particles. Science 183: 202–204 (1974).
G. L. Fisher and C. E. Chrisp, Physical and Biological Studies of Coal Fly Ash, in: “Applications of Short-Term Bioassay in the Fractionation of Complex Environmental Mixture,” M. D. Waters, S. Nesnow, J. L. Huisingh, S. S. Sandhu,, L. Claxton, eds., Plenum Publishing Co., New York, NY, 443–462, (1979).
O. G. Raabe, Physical Properties of Aerosols Affecting Inhalation Toxicology, in: “Pulmonary Toxicology of Respirable Particles,” CONF-791002, C. L. Sanders et al., eds., Technical Information Center, US Department of Energy, 1–28 (1980), ( Available from National Technical Information Service, Springfield, VA 22161 ).
O. G. Raabe, Physical Properties of Aerosols Affecting Inhalation Toxicology, in: “Pulmonary Toxicology of Respirable Particles,” CONF-791002, C. L. Sanders et al., eds., Technical Information Center, US Department of Energy, 1–28 (1980), ( Available from National Technical Information Service, Springfield, VA 22161 ).
O. G. Raabe, Deposition and Clearance of Inhaled Aerosols, Laboratory for Energy-Related Health Research, University of California, Davis, CA, UCD 472-503, 1–60 (1979). ( Available from National Technical Information Service, Springfield, VA 22161 ).
P. E. Morrow, D. V. Bates, B. R. Fish, T. E. Hatch, T. T. Mercer, (International Commission on Radiological Protection Task Group on Lung Dynamics) - Deposition and retention models for internal dosimetry of the human respiratory tract. Health Physics 12: 173 (1966).
J. N. Pitts, Jr., K. A. Van Cauwenberghe, D. Grosjean J. P. Schmid, D. R. Fitz, W. L. Belser, Jr., G. B. Knudson, P. M. Hynds, Atmospheric reactions of poly- cyclic aeromatic hydrocarbons: facile formations of mutagenic nitro derivatives. Science 202: 515–519 (1978).
J. N. Pitts, Jr., D. M. Lokensgard, P. S. Ripley, K. A. Van Cauwenberghe, L. Van Vaeck, S. D. Schaffer, A. J. Thill, W. L. Belser, Jr., Atmospheric expoxidations of benzo(a)pyrene by ozone: formation of the metabolite benzo(a)pyrene-4,5-oxide. Science 210; 1347–1349 (1980).
G. L. Fisher, C. E. Chrisp, O. G. Raabe, Physical factor affecting the mutagenecity of fly ash from a coal-fired power plant. Science 204: 879–881 (1979).
O. G. Raabe, Generation and Characterization of Power Plant Fly Ash, in: “Generation of Aerosol”, K. Willeke, ed., Ann Arbor Science Publishers, Inc., Ann Arbor, MI 215–234 (1980).
T. L. Chan, P. S. Lee , J. S. Siak, Diesel Particulate Collection for Biological Testing: Comparison of Electro-static Precipitation and Filtration, GMR-3182, General Motors Research Laboratories, Warraen, MI 48090.
M. Novotny, M. L. Lee , K. D. J. Bartle, The methods for fractionation, analytical separation and identification of polynuclear aromatic hydrocarbons and complex mixtures. Chromat. Sci. 12:606–612 (1974).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1982 Plenum Press, New York
About this chapter
Cite this chapter
Raabe, O.G. (1982). Problems Associated with Assessing the Mutagenicity of Inhalable Particulate Matter. In: Tice, R.R., Costa, D.L., Schaich, K.M. (eds) Genotoxic Effects of Airborne Agents. Environmental Science Research, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3455-2_17
Download citation
DOI: https://doi.org/10.1007/978-1-4613-3455-2_17
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-3457-6
Online ISBN: 978-1-4613-3455-2
eBook Packages: Springer Book Archive