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Comparative Mutagenicity of TEPA, ThioTEPA, and MeTEPA

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Comparative Chemical Mutagenesis
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Abstract

All the three chemicals are typical of alkylating compounds and their molecules contain three ethylenimine functional groups.

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References

  1. Mellet, L. B., and Woods. L. A. Cancer Res. 20: 524–532 (1960).

    Google Scholar 

  2. Kirichenko, O. P., Chebotarev, A. N., and Yakovenko, K. N. Byull. Eksptl. Biol. Med. 81 552–553 (1976).

    Article  Google Scholar 

  3. Hanna, P. J., and Dyer, K. F. Mutat. Res. 28: 405–420 (1975)

    Article  Google Scholar 

  4. McCann, J., Choi, E., Yamasaki, E., and Ames, B. N. Proc. Natl. Acad. Sci (U.S.A.) 72 5135–1539 (1975).

    Article  ADS  Google Scholar 

  5. Specht, J. Arch. Microbiol. 51 9–17 (1965).

    Article  Google Scholar 

  6. Price, K. E., Buck, R. E., and Lein, J. Antimicrob. Agents Chemotherap. 1965: 505–517.

    Google Scholar 

  7. Letterberg, G. EMS Newsletter 3: 14–15 (1970).

    Google Scholar 

  8. Kihlman, B. In: Chemical Mutagens-Principles and Methods for Their Detection, A. Hollaender, Ed., Plenum Press, New York, 1971, Vol. 2, pp. 489–515.

    Google Scholar 

  9. Ninan, T., and Wilson, G. B. Genetika (Hague), 40: 103–119. (1969).

    Google Scholar 

  10. Sturelid, S., and Kihlman, B. EMS Newsletter 3: 15–17 (1970)

    Google Scholar 

  11. Sturelid, S. Hereditas 68: 255–276 (1971).

    Article  Google Scholar 

  12. Sidorov, B. N., Sokolov, N. N., and Andreev, V. S. Sov. Genet. 2: 81–87 (1966); translated from Genetika 2: 124–133 (1966).

    Google Scholar 

  13. Asp, B. Mutat. Res. 21: 22 (1973).

    Google Scholar 

  14. Kihlman, B. A., Hartley-Asp, B., Nilssen, K., and Sturelid, S. Mutat. Res. 21: 191–192 (1973).

    Google Scholar 

  15. Kihlman, B. A., Sturelid, S., Hartley-Asp, B., and Nilsson, K. Mutat. Res. 17: 271–275 (1973).

    Article  Google Scholar 

  16. Kihlman, B. A., Sturelid, S., Hartley-Asp, B., and Nilsson, K. Mutat. Res. 26 (2): 105–122 (1974).

    Article  Google Scholar 

  17. Deysson, G. C. R. Soc. Biol. 168: 687–693 (1974).

    Google Scholar 

  18. Sturelid, S., and Kihlman, B. A. Hereditas 79: 29–42 (1975).

    Article  Google Scholar 

  19. Sturelid, S., and Kihlman, B. A. Hereditas 80: 233–246 (1975).

    Article  Google Scholar 

  20. Kihlman, B. A. Chromosoma 51 (1): 11–18 (1975).

    Article  Google Scholar 

  21. Kihlman, B. A., Sturelid, S., Palitti, F., and Becchetti, A. Mutat. Res. 46: 130–131 (1977).

    Google Scholar 

  22. Sturelid, S., and Kihlman, B. A. Mutat. Res. 53 (2): 270 (1978).

    Google Scholar 

  23. Kihlman, B. A., and Sturelid, S. Hereditas 88(1): 35 (1978).

    Google Scholar 

  24. Hartley-Asp, B. Hereditas 83: 223–236 (1976).

    Article  Google Scholar 

  25. Benes, V., and Šram, R. Ind. Med. 38: 50–52 (1969).

    Google Scholar 

  26. Kocisova, J., and Šram, R. J. Folia Biol. (Prague) 20: 325–332 (1974).

    Google Scholar 

  27. Fahmy, O. G., and Fahmy, M. J. Cancer Res. 30: 195 (1970).

    Google Scholar 

  28. LUers, H., and Rohrborn, G. Proceedings Xlth Intern. Congr. Genetics 1: 64–65.

    Google Scholar 

  29. Luers, H., and Rohrborn, G. Mutat. Res. 2: 29–44 (1965).

    Article  Google Scholar 

  30. Adler, I. D., Ramarao, G., and Epstein, S. S. Mutat. Res. 13 (3): 263–270 (1971).

    Article  Google Scholar 

  31. Generoso, W. M., Cain, K. T., Huff, S. W., and Gosslee, D. T. In: Advances in Modern Toxicology, 1 (1977).

    Google Scholar 

  32. Sram, R. Unpublished data.

    Google Scholar 

  33. Arseniyeva, M. A., And Golovkina, A. V. In: Vliyanie Ioniz. Izluch. Nasledstvennost, Akad. Nauk SSSR, 1966, pp. 1–122 (Russian).

    Google Scholar 

  34. Arsenieva, M. A., Bakulina, E. D., Golovkina, A. V., and Lander, E. S. Genetika 5: 111–121 (1967).

    Google Scholar 

  35. Surkova, N. I., and Malashenko, A. M. Genetika 10 (2): 81–89 (1974).

    Google Scholar 

  36. Surkova, N. J., and Malashenko, A. M. Genetika 11 (11): 66–72 (1975).

    Google Scholar 

  37. Maier, P., and Schmid, W. Mutat. Res. 40: 325–338 (1976).

    Article  Google Scholar 

  38. Manna, G. K., Das, K. P., and Pradeep, K. Proc. Indian Sci. Congr. 60: 676 (1973).

    Google Scholar 

  39. Richardson, J. C. Mutat. Res. 26 (5): 391–394 (1974).

    Article  Google Scholar 

  40. Epstein, S. S., and Shafner, H. Nature 219: 385 (1968).

    Article  ADS  Google Scholar 

  41. Epstein, S. S. Toxicol. Appl. Pharmacol. 653 (1969).

    Google Scholar 

  42. Epstein, S. S., Arnold, E., Andrea, J., Bass, W., and Bishop, Y. Toxicol. Appl. Pharmacol, 23: 288 (1972).

    Article  Google Scholar 

  43. Å ram, R. J., Zudova, Z., and Benes, V. Folia Biol. 16: 367 (1970).

    Google Scholar 

  44. Å ram, R. J., Benes, V., and Zudova, Z. Folia Biol. 16: 407 (1970).

    Google Scholar 

  45. Å ram, R. J. Folia Biol. 18: 367 (1972).

    Google Scholar 

  46. Šram, R. J. Folia Biol. 18: 139–148 (1972).

    Google Scholar 

  47. Joshi, S. R., Page, E. C., Arnold, E., Bishop, Y., and Epstein, S. S. Genetics 65: 483 (197).

    Google Scholar 

  48. Å ram, R. J., and Zudova, Z. Folia Biol. 19: 58 (1973).

    Google Scholar 

  49. Epstein, S. S., Joshi, S. R., Arnold, E., Page, E. C., and Bishop, Y. Nature 225: 1260 (1970).

    Article  ADS  Google Scholar 

  50. Epstein, S. S., Bass, W., Arnold, E., Bishop, Y., Joshi, S., and Adler, I. D. Toxicol. Appl. Pharmacol. 19: 134 (1971).

    Article  Google Scholar 

  51. Epstein, S. S., Arnold, E., Steinberg, K., Mackintosh, D., Shafner, H., and Bishop, Y. Toxicol. Appl. Pharmacol. 17: 23 (1970).

    Article  Google Scholar 

  52. Å ram, R. J. Mutat. Res. 41: 25 (1976).

    Article  MathSciNet  ADS  Google Scholar 

  53. Malashenko, A. M., and Surkova, N. I. Genetika 10 (1): 71–79 (1974).

    Google Scholar 

  54. Malashenko, A. M., and Surkova, N. I. Genetika 10 (8): 92 (1974).

    Google Scholar 

  55. Semenov, Kh. Kh., and Malashenko, A. M. Byull. Eksptl. Biol. Med. 80: No. 10, 107–110 (1975).

    Google Scholar 

  56. Ehling, V. H. Mutat. Res. 11: 35 (1971).

    Article  Google Scholar 

  57. Malashenko, A. M., and Surkova, N. I. Genetika 10 (2): 105–111 (1975).

    Google Scholar 

  58. Malashenko, A. M., Semenov, Kh. Kh., Selezneva, G. P., and Surkova, N. I. Genetika (U.S.S.R.), 14 (1): 52–55 (1978).

    Google Scholar 

  59. Wallenstein, S., Brobst, J., and Bagdon, R. E. Mutat. Res. 26: 458 (1974).

    Google Scholar 

  60. Selezneva, T. G., and Korman, N. P. Genetika (U.S.S.R.) 9: No. 12, 112–118 (1973).

    Google Scholar 

  61. Chang, T.-H., and Klassen, W. Chromosoma 24: 314–323 (1968).

    Article  Google Scholar 

  62. Hampel, K. E., and Stopic, D. Haematol. 46: 136–141 (1971).

    Google Scholar 

  63. Kucerova, M., and Polivkova, Z. Mutat. Res. 34: 279–290 (1976).

    Article  Google Scholar 

  64. Selezneva, T. G., and Chebotarev, A. N. Byull. Eksptl. Biol. Med. 82: 1265–1267 (1976).

    Article  Google Scholar 

  65. Dubinina, L. G. Sov. Genet. 10: 1428–1436 (1974); translated from Genetika 10 (11): 129–137 (1974).

    Google Scholar 

  66. Zhurkov, V. S., and Yakovenko, K. N. Mutat. Res. 1107–1112 (1976).

    Google Scholar 

  67. Bochkov, N. P., and Yakovenko, K. N. In: Mutagen-Induced Chromosome Damage in Man. Evans and Lloyd, Eds, Edinburgh University Press, 1978, pp. 290–295.

    Google Scholar 

  68. Bochkov, N. P., Yakovenko, K. N., Chebotarev, A. N., Kravioto, F. F., Zhurkov, V. S. Sov. Genet. 8: 1595–1601 (1972); translated from Genetika 8(12): 160–168 (1972).

    Google Scholar 

  69. Chebotarev, A. N., and Yakovenko, K. N. Sov. Genet. 10: 1048–1054 (1974); translated from Genetika, 10(8): 150–157 (1974).

    Google Scholar 

  70. Kirichenko, O. P. Sov. Genet. 10: 1172–1175 (1974); translated from Genetika 10(9): 139–143 (1974).

    Google Scholar 

  71. Kirichenko, O. P., and Chebotarev, A. N. Genetika 12 (6): 142–149 (1976).

    Google Scholar 

  72. Chebotarev, A. N. Sov. Genet. 10: 1178–1182 (1974); translated from Genetika 10(9): 147–153 (1974).

    Google Scholar 

  73. Yakovenko, K. N., Tarusina, T. O., and Kuleshov, N. P. Genetika 12 (12): 139–143 (1976).

    Google Scholar 

  74. Bochkov, N. P., and Kuleshov, N. P. Mutat. Res. 14: 345–353 (1972).

    Article  Google Scholar 

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© 1981 Plenum Press, New York

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Bochkov, N.P. (1981). Comparative Mutagenicity of TEPA, ThioTEPA, and MeTEPA. In: De Serres, F.J., Shelby, M.D. (eds) Comparative Chemical Mutagenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3409-5_31

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  • DOI: https://doi.org/10.1007/978-1-4613-3409-5_31

  • Publisher Name: Springer, Boston, MA

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