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Mutagenicity of Selected Chemicals in In Vivo Cytogenetic Assays

  • Chapter
Comparative Chemical Mutagenesis

Abstract

There are a variety of test systems available for the analysis of chromosome aberrations following in vivo treatment. There are advantages and disadvantages to each, which means that the information obtained from any one test must be critically examined. Because of the variety of test systems employed, it is also impossible to provide a concise summary of the effect of each of the chemicals under study.

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Authors and Affiliations

  1. Biology Division, Gesellschaft fur Strahlen-und Umweltforschung, Oak Ridge, Tennessee, 37830, USA

    R. J. Preston

  2. Gesellschaft fur Strahlen-und Umweltforschung, Munich, West Germany

    I.-D. Adler

  3. Laboratory of Genetics, Department of Radiobiology, C.E.N./S.C.K, B-2400, Mol, Belgium

    A. Léonard

  4. Radiobiology Unit, Medical Research Council, Harwell Didcot, Oxon, 0X 11 0RD, England

    M. F. Lyon

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  1. R. J. Preston
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  3. A. Léonard
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  1. National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA

    Frederick J. De Serres  & Michael D. Shelby  & 

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Preston, R.J., Adler, ID., Léonard, A., Lyon, M.F. (1981). Mutagenicity of Selected Chemicals in In Vivo Cytogenetic Assays. In: De Serres, F.J., Shelby, M.D. (eds) Comparative Chemical Mutagenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3409-5_20

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