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The Pleura: Mesothelial Cells and Mesothelioma

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Cellular Biology of the Lung

Part of the book series: Ettore Majorana International Science Series ((SIOR,volume 1))

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Abstract

Whereas cell biology and biochemistry of the lung parenchyma is now well documented, little work has been carried out on the pleura. The biological reactivity of pleural cells and the physiology of the pleural space however are of paramount importance, in relation to three main conditions of the pleura: effusions, fibrosis and cancer. The highly significant association of these conditions with past exposure to airborn mineral fibres explains the interest of many workers in pleura, particularly in the field of experimental and human pathology and, more recently that of basic research. According to the work carried out in our laboratory and in others, the structure and function of the pleura will be examined in four parts: 1 - pleural cells in situ and in vitro; 2 - mesothelial barrier, in relation to fluid movement and particulate matters clearance; 3 - inflammatory lesions of the pleura; 4 - pleural carcinogenesis.

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© 1982 Plenum Press, New York

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Bignon, J., Bernaudin, JF., Jaurand, MC., Pinchon, MC. (1982). The Pleura: Mesothelial Cells and Mesothelioma. In: Cumming, G., Bonsignore, G. (eds) Cellular Biology of the Lung. Ettore Majorana International Science Series, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3403-3_8

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  • DOI: https://doi.org/10.1007/978-1-4613-3403-3_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3405-7

  • Online ISBN: 978-1-4613-3403-3

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