Lavage Eosinophils and Histamine

  • P. L. Haslam
  • A. Dewar
  • M. Turner-Warwick
Part of the Ettore Majorana International Science Series book series (SIOR, volume 1)


In recent years, development of the technique of bronchoalveolar lavage has provided a simple and safe way of obtaining samples of inflammatory cells and other components which accumulate in the air spaces of the lungs as a consequence of disease. These components can be examined free from the tissues, and are providing a great deal more information about inflammatory processes in different lung disorders. In particular, bronchoalveolar lavage has been used to study interstitial disorders of the lung including granulomatous lung disorders, namely sarcoidosis and extrinsic allergic alveolitis and interstitial fibrosing lung disorders, including asbestosis and cryptogenic fibrosing alveolitis (synonym: idiopathic pulmonary fibrosis). One of the main findings in these samples is that while lavage lymphocyte increases are a striking feature of the granulomatous lung disorders, by contrast lavage neutrophil increases are the most striking feature of interstitial fibrosis1.


Immune Complex Idiopathic Pulmonary Fibrosis Interstitial Lung Disease Lavage Fluid Eosinophil Cationic Protein 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • P. L. Haslam
    • 1
    • 2
  • A. Dewar
    • 1
    • 2
  • M. Turner-Warwick
    • 1
    • 2
  1. 1.Department of MedicineCardiothoracic InstituteLondonUK
  2. 2.Department of Electron MicroscopyCardiothoracic InstituteLondonUK

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