Abstract
Our studies show that under certain circumstances normal nutrients may have adverse effects on host resistance. Undernutrition and deficiencies of certain nutrients may protect the host against intracellular infections, while refeeding with normal foods and repletion of nutrient deficiencies seem to have the potential for activating quiescent disease. In some societies, long standing deficiencies of nutrients are part of an ecological compromise favoring optimum co-existence of host and pathogens. Once this equilibrium is disturbed by upgrading nutritional status, disease may erupt with unusual violence.
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References
Diamond, L. S., Harlow, D. R., and Phillips, B. P., 1978. Entamoeba histolytica: Iron and nutritional immunity, Arch. Invest. Med. (Mex) 9 (Suppl. 2): 329–338.
Falchuk, K. H., Fawcett, D. W., and Vallee B. L., 1975, Role of zinc in cell division of Euglena gracilis, J. Cell Sci. 17: 52–78.
Felton, C., Lustbader, E. D., Marten, C., and Blumberg, B. S., 1979, Serum iron levels and responses to hepatitis B virus, Proc. Nat. Acad. Sci. U.S.A. 76: 2438–2441.
Hawking, F., 1953, Milk diet, para-aminobenzoic acid and malaria (P. berghei), Br. Med. J. 1: 1201–1202.
Lutwick, L. I., 1979, Relation between aflatoxin, hepatitis B virus and hepatocellular carcinoma, Lancet 1: 755–757.
Mackee, R. W., 1949, Biochemistry and metabolism of malarial parasites, in: Parasitic Infections in Man (H. Most, ed.), p. 123, NY Acad. Med., Symposium on Microbiology No. 4.
Masawe, A. E. J., Muindi, J. M., and Swai, G. B. R., 1974, Infections in iron deficiency and other types of anaemia in the tropics, Lancet 2: 314–316.
Mathews, T. H. J., Nair, C. D. G., Lawrence, M. K., and Tyrrell, D. A. G., 1976, Antiviral activity in milk of possible clinical importance, Lancet 2: 1387–1389.
Murray, M. J., and Murray, A. B., 1981, Dietary trypsin-inhibitors: A clue to nutritional enlargement of the parotids, Clin. Res. 29: 627a.
Murray, M. J., Murray, A. B., Murray, N. J., and Murray, M. B., 1975, Refeeding malaria and hyperferremia, Lancet 1: 653–655.
Murray, M. J., Murray, A. B., Murray, M. B., and Murray, C. J., 1976, Somali food shelters in the Ogaden and their impact on health, Lancet 1: 1283–1285.
Murray, M. J., Murray, A. B., Murray, M. B., and Murray, C. J., 1977, Parotid enlargement, forehead edema and suppression of malaria as nutritional consequences of ascariasis, Am. J. Clin. Nutr. 30: 2117–2121.
Murray, M. J., Murray, A. B., Murray, M. B., and Murray, C. J., 1978a, The adverse effects of iron repletion on the course of certain infections, Br. Med. J. 2: 1113–1115.
Murray, M. J., Murray, A. B., Murray, N. J., and Murray, M. B., 1978b, Diet and cerebral malaria—the effect of famine and refeeding, Am. J. Clin. Nutr. 31: 57–61.
Murray, M. J., Murray, A. B., Murray M. B., and Murray, C. J., 1978c, The biological suppression of malaria: An ecological and nutritional interrelationship of a host and two parasites, Am. J. Clin. Nutr. 31: 1363–1366.
Murray, M. J., Murray, A. B., and Murray, C. J., 1980a, The salutary effect of milk on amebiasis and its reversal by iron, Br. Med. J. 1: 1351–1352.
Murray, M. J., Murray, A. B., and Murray, N. J., 1980b, The ecological interdependence of diet and disease in tribal societies, Yale J. Biol. Med. 53: 295–306.
Murray, M. J., Murray A. B., Murray, N. J., Murray, M. B., and Murray, C. J., 1980c, Molluscum contagiosum and herpes simplex in Maasai pastoralists: Refeeding activation of virus infection following famine? Trans. R. Soc. Trop. Med. Hyg. 74: 371–374.
Murray, M. J., Murray, A. B., Murray, M. B., and Murray, C. J., 1980d, Rarity of planar warts in Cushite nomads: Antiviral effect of milk? Lancet 2: 143–144.
Ramakrishnan, S. P., 1953, Studies on Plasmodium berghei N. SP. Vincke and lips 1948, VIII. The course of blood induced infections in starved albino rats. Indian J. Malariol. 7: 53–60.
Ramakrishnan, S. P., 1954, Studies on Plasmodium berghei Vincke and lips 1948, XVII. Effect of different quantities of the same diet on the course of blood induced infection in rats, Indian J. Malariol. 8: 89–96.
Ramakrishnan, S. P., Prabash, S., Krishnaswamie, S. P., and Sing, L. C., 1953, Studies on Plasmodium berghei Vincke and lips 1948, XIII. Effect of glucose, biotin, para-aminobenzoic acid and methionine on the course of blood induced infection in starving albino rats, Indian J. Malariol. 7: 225–231.
Speert, D. P., Wannamacher, L. W., Gray, E. D., and Clawson, C. C., 1979, Bactericidal effect of oleic acid on group A streptococci: Mechanism of action, Infect. Immun. 26: 1202–1210.
Trousseau, A., 1872, Lectures on Clinical Medicine, p. 96, New Sydenham Society, London.
Waldman, E., 1980, personal communication, Save The Children Fund, Tsim Sha Tsui, Hong Kong.
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© 1982 Plenum Press, New York
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Murray, M.J., Murray, A.B., Murray, N.J., Murray, M.B., Murray, C.J. (1982). Adverse Effects of Normal Nutrients and Foods on Host Resistance to Disease. In: Jelliffe, E.F.P., Jelliffe, D.B. (eds) Adverse Effects of Foods. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3359-3_28
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DOI: https://doi.org/10.1007/978-1-4613-3359-3_28
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