Metamorphosis pp 445-459 | Cite as

Transitions in the Nervous System during Amphibian Metamorphosis

  • Jerry J. Kollros

Abstract

The tadpole as a whole can be considered to be an aggregate of mosaic territories, each responding in a distinctive way to the increased titers of thyroid hormones (TH) responsible for progressive metamorphic changes. Similarly, the separate elements of the nervous system can be considered, at least as a first approximation, to be composed of a series of mosaic territories. They differ as to the stages when they are first morphologically distinguishable, when they first acquire capacity to respond to TH, in the rates of increase in such sensitivity, i.e., in reduction of threshold concentrations required to elicit detectable change, and in the rates of response to given concentrations. They probably also differ with respect to the hormone concentrations required to elicit maximal rates of tissue response. Some elements of the nervous system grow and differentiate; others shrink, die, and disappear. The extent to which there may be elements of the nervous system that are unresponsive to TH remains largely to be established.

Keywords

Cholesterol Migration Respiration Aldehyde Shrinkage 

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References

  1. Allen, B. M., 1918, J. Exp. Zool. 24: 499.CrossRefGoogle Scholar
  2. Allen, B. M., 1924, Endocrinology 8: 639.CrossRefGoogle Scholar
  3. Alley, K. E., 1974, J. EmbryoL Exp. Moiphol. 31: 99.Google Scholar
  4. Baffoni, G. M., 1957, Atti Accad. Naz. Lincei Rc. Ser. VIII 23: 495.Google Scholar
  5. Baffoni, G. M., and Catte, G., 1950, Atti Accad. Naz. Lincei Rc. Sci. VIII 9: 282.Google Scholar
  6. Baffoni, G. M., and Catte, G., 1951, Riv. Biol. 43: 373.Google Scholar
  7. Baffoni, G. M., and Elia, E., 1957, Atti Accad. Naz. Lincei Rc. Ser. VIII 22: 109.Google Scholar
  8. Beach, D. H., and Jacobson, M., 1979, J. Comp. Neurol. 183: 615.CrossRefGoogle Scholar
  9. Beaudoin, A. R., 1956, Anat. Rec. 125: 247.CrossRefGoogle Scholar
  10. Bibb, H. D., 1963, The mesencephalic V nucleus in Ambystoma jeffersonianum, M.S. Thesis, University of Iowa, Iowa City.Google Scholar
  11. Bibb, H. D., 1977, J. Exp. Zool. 200: 265.CrossRefGoogle Scholar
  12. Champy, C, 1922, Arch. Morphol. Gen. Exp. 4: 1.Google Scholar
  13. Cooksey, W. B., 1922, Endocrinology 6: 391.CrossRefGoogle Scholar
  14. Decker, R. S., 1974a, J. Cell Biol. 61: 599.CrossRefGoogle Scholar
  15. Decker, R. S., 1974b, Dev. Biol. 41: 146.CrossRefGoogle Scholar
  16. Decker, R. S., and Kollros, J. J., 1969, J. Embryol. Exp. Morphol. 21: 219.Google Scholar
  17. Etkin, W., 1966, Neuroendocrinology 1: 293.CrossRefGoogle Scholar
  18. Faber, D. S., and Korn, H., 1978, Neurobiology of the Mauthner Cell, Raven Press, New York.Google Scholar
  19. Ferguson, T., 1966, Gen. Comp. Endocrinol. 7: 74.CrossRefGoogle Scholar
  20. Gona, A. G., 1972, J. Comp. Neurol. 146: 133.CrossRefGoogle Scholar
  21. Gona, A. G., 1973, Exp. Neurol. 38: 494.CrossRefGoogle Scholar
  22. Gona, A. G., 1977, in: Thyroid Hormones and Brain Development (G. D. Grave, ed.), pp. 107–117, Raven Press, New York.Google Scholar
  23. Grave, G. D., (ed.), 1977, Thyroid Hormones and Brain Development, Raven Press, New York.Google Scholar
  24. Harms, W., 1923, Zool. Anz. 56: 136.Google Scholar
  25. Hughes, A. F., 1961, J. Embryol. Exp. Morphol. 9: 269.Google Scholar
  26. Hughes, A. F., 1968, Aspects of Neural Ontogeny, Logos Press Limited, London.Google Scholar
  27. Hughes, A. F., 1977, in: Frog Neurobiology (R. Llinäs and W. Precht, eds.), pp. 856–863,Google Scholar
  28. Springer-Verlag, Berlin. Hughes, A. F., and Prestige, M. C., 1967, J. Zool. 152: 347.Google Scholar
  29. Jacobson, M., 1978, Developmental Neurobiology, Plenum Press, New York.Google Scholar
  30. Kaltenbach, J. C., 1953a, J. Exp. Zool. 122: 21.CrossRefGoogle Scholar
  31. Kaltenbach, J. C., 1953b, J. Exp. Zool. 122: 41.CrossRefGoogle Scholar
  32. Kaltenbach, J. C., and Hobbs, A. W., 1972, J. Exp. Zool. 179: 157.CrossRefGoogle Scholar
  33. Kollros, J. J., 1942, J. Exp. Zool. 89: 37.CrossRefGoogle Scholar
  34. Kollros, J. J., 1943, J. Exp. Zool. 92: 121.CrossRefGoogle Scholar
  35. Kollros, J. J., 1956, in: Normal Table of Xenopus laevis (Daudin) (P. D. Nieuwkoop and J. Faber, eds.), pp. 67–73, North-Holland, Amsterdam.Google Scholar
  36. Kollros, J. J., 1957, Proc. Soc. Exp. Biol. Med. 95: 138.Google Scholar
  37. Kollros, J. J., 1958, Science 128: 1505.CrossRefGoogle Scholar
  38. Kollros, J. J., 1961, Am. Zool. 1: 107.Google Scholar
  39. Kollros, J. J., 1966, Am. Zool. 4: 553.Google Scholar
  40. Kollros, J. J., 1968, in: The Emergence of Order in Developing Systems (M. Locke, ed.), pp. 272–305, 27th Symposium of the Society for Developmental Biology, Academic Press, New York.Google Scholar
  41. Kollros, J. J., 1977, in: Thyroid Hormones and Brain Development (G. D. Grave, ed.), pp. 119–136, Raven Press, New York.Google Scholar
  42. Kollros, J. J., 1979, Am. Zool. (abstract) 19: 979.Google Scholar
  43. Kollros, J. J., and McMurray, V., 1955, J. Comp. Neurol. 102: 47.CrossRefGoogle Scholar
  44. Kollros, J. J., and McMurray, V., 1956, J. Exp. Zool. 131: 1.CrossRefGoogle Scholar
  45. Kollros, J. J., and Race, J., Jr., 1960, Anat. Rec. 136: 224.Google Scholar
  46. Larsell, O., 1925, J. Comp. Neurol. 39: 249.CrossRefGoogle Scholar
  47. Moulton, J. M., Jurand, A., and Fox, H., 1968, J. Embryol. Exp. Morphol. 19: 415.Google Scholar
  48. Norman, L. K., 1966, Effects of thyroid hormone on spinal ganglia in Rana pipiens, M.S. thesis, University of Iowa, Iowa City.Google Scholar
  49. Ohtsu, K., Naito, K., and Wilt, F., 1964, Dev. Biol. 10: 216.CrossRefGoogle Scholar
  50. Pesetsky, I., 1962, Gen. Comp. Endocrinol. 2: 228.CrossRefGoogle Scholar
  51. Pesetsky, I., 1966, Z. Zellforsch. Mikrosk. Anat. 75: 138.CrossRefGoogle Scholar
  52. Pesetsky, I., and Kollros, J. J., 1956, Exp. Cell Res. 11: 477.CrossRefGoogle Scholar
  53. Piatt, J., 1945, J. Comp. Neurol. 82: 35.CrossRefGoogle Scholar
  54. Pollack, E., and Kollros, J. J., 1975, J. Exp. Zool. 192: 299.CrossRefGoogle Scholar
  55. Prestige, M. C., 1965, J. Embryol. Exp. Morphol. 13: 63.Google Scholar
  56. Prestige, M. C., 1967, J. Embryol. Exp. Morphol. 18: 359.Google Scholar
  57. Race, J., Jr., 1961, Gen. Comp. Endocrinol. 1: 322.CrossRefGoogle Scholar
  58. Reynolds, W. A., 1963, J. Exp. Zool. 153: 237.CrossRefGoogle Scholar
  59. Rogers, L. A., and Cowan, W. M., 1973, J. Comp. Neurol. 147: 291.CrossRefGoogle Scholar
  60. Schulze, W., 1924, Arch. Mikrosk. Anat. Entwicklungsmech. 101: 338.CrossRefGoogle Scholar
  61. Shumway, W., 1940, Anat. Rec. 78: 139.CrossRefGoogle Scholar
  62. Stefanelli, A., 1951, Q. Rev. Biol. 26: 17.CrossRefGoogle Scholar
  63. Stephens, L. B., Jr., 1965, Am. Zool 5: 222.Google Scholar
  64. Suter, J., 1966, Numbers and distribution of Rohon-Beard cells in selected larval stages of Rana pipiens, M.S. thesis, University of Iowa, Iowa City.Google Scholar
  65. Taylor, A. C., and Kollros, J. J., 1946, Anat. Rec. 94: 7.CrossRefGoogle Scholar
  66. Trevisan, P., 1973, Atti Accad. Naz. Lincei Rend. CI. Sci. Fis. Mat. Nat. Sez. III 53: 217.Google Scholar
  67. Wald, G., 1946, Harvey Lect. 42: 148.Google Scholar
  68. Weber, R., 1967, in: The Biochemistry of Animal Development, Volume 2 (R. Weber, ed.), pp. 227–301, Academic Press, New York.Google Scholar
  69. Weiss, P., and Rossetti, F., 1951, Proc. Natl. Acad. Sci. USA 37: 540.CrossRefGoogle Scholar
  70. Wilt, F. H., 1959, J. Embryol. Exp. Morphol. 7: 556.Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Jerry J. Kollros
    • 1
  1. 1.Department of ZoologyUniversity of IowaIowa CityUSA

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