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Respiratory Syncytial Virus

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Book cover Viral Infections of Humans

Abstract

Respiratory syncytial virus (RSV) was first isolated from a chimpanzee with common-cold-like illness.(77) Shortly thereafter, the virus was recovered from young children with severe lower respiratory tract disease in Baltimore.(16,21) Since its initial isolation from infants with respiratory disease almost 23 years ago, RSV has emerged as the major lower respiratory tract pathogen of infancy and early childhood throughout the world(3,18,19,29,36,39,60,69,70,98,100) It is now clear that in all geographic areas, RSV is the major cause of bronchiolitis and pneumonia in infants and young children. RSV presents a special challenge to the epidemiologist, since this virus exhibits a pattern of infection and disease unlike that of any of the other known respiratory tract viral pathogens. Unanswered are many pressing questions concerning the pathogenesis of serious life threatening disease of the lower respiratory tract produced by this virus during early infancy A safe, effective vaccine for prevention of serious, pediatric RSV illness is not available at this time. However, studies now in progress offer some hope that ultimately it should be possible to develop effective immunoprophylaxis for RSV bronchiolitis and pneumonia

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Authors and Affiliations

  1. Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

    Robert M. Chanock, Hyun Wha Kim, Carl D. Brandt & Robert H. Parrott

  2. Children’s Hospital National Medical Center of Washington, D.C., USA

    Robert M. Chanock, Hyun Wha Kim, Carl D. Brandt & Robert H. Parrott

  3. Department of Child Health and Development, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA

    Robert M. Chanock, Hyun Wha Kim, Carl D. Brandt & Robert H. Parrott

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  1. Robert M. Chanock
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  2. Hyun Wha Kim
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  3. Carl D. Brandt
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  4. Robert H. Parrott
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Editors and Affiliations

  1. WHO Serum Reference Bank, Section of International Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA

    Alfred S. Evans

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© 1982 Plenum Publishing Corporation

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Chanock, R.M., Kim, H.W., Brandt, C.D., Parrott, R.H. (1982). Respiratory Syncytial Virus. In: Evans, A.S. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3237-4_19

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  • DOI: https://doi.org/10.1007/978-1-4613-3237-4_19

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