Abstract
That the blastocyst and the uterus exchange information prior to implantation is suggested by the greater increase in secretion of progesterone in pregnant than in pseudopregnant rabbits on Days 4 to 6 and by the secondary rise of CG-LH-like material in the serum of pregnant rabbits on Days 3 and 4 postcoitum (Singh and Adams, 1978; Varma et al., 1979). The maintenance of the corpus luteum of pregnancy in the presence of blastocysts in the oviduct and after transplantation of the blastocyst under the kidney capsule in the rabbit suggests that the blastocyst may be the source of luteotropic stimuli prior to implantation (Zielmaker and Verhamme, 1978). Dickmann and Dey (1974) suggested that steroidogenesis in the rabbit blastocyst may be activated by a gonadotropic material of blastocyst origin.
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References
Asch, R. H., Fernandez, E. O., Magnasco, L. A., and Pauerstein, C. J., 1978, Demonstration of a chorionic gonadotropin-like substance in rabbit morulae, Fertil. Steril. 29: 123.
Asch, R. H., Fernandez, E. O., Siler-Khodr, T. M., and Pauerstein, C. J., 1979a, Evidence for a human chorionic gonadotropin-like material in the rabbit blastocyst, Fertil. Steril. 32: 697.
Asch, R. H., Fernandez, E. O., Siler-Khodr, T. M., and Pauerstein, C. J., 1979b, Presence of an hCG-like substance in human sperm, Am. J. Obstet. Gynecol. 135: 1041.
Beer, A. E., and Billingham, R. E., 1978, Immunoregulatory aspects of pregnancy, Fed. Proc. Fed. Am. Soc. Exp. Biol. 37: 2374.
Catt, K. J., Dufau, M. L., and Tsuruhara, T., 1972, Radioligand receptor assay of LH and chorionic gonadotropin, J. Clin. Endocrinol. Metab. 34: 123.
Channing, C. P., Stone, S. L., Sakai, C. N., Haour, F., and Saxena, B. B., 1978, A stimulatory effect of the fluid from preimplantation rabbit blastocysts upon luteinization of monkey granulosa cell cultures, J. Reprod. Fertil. 54: 477.
Dickmann, Z., and Dey, S. K., 1974, Steroidogenesis in the preimplantation rat embryo and its possible influence on the morula-blastocyst transformation and implantation, J. Reprod. Fertil. 37: 91.
Fujimoto, S., Euker, J. S., Riegle, G. D., and Dukelow, W. R., 1975, On a substance cross-reacting with luteinizing hormone in the preimplantation blastocyst fluid of the rabbit, Proc. Jpn. Acad. Sci. 51: 123.
Haour, F., and Saxena, B. B., 1974, Detection of a gonadotropin in rabbit blastocyst before implantation. Science 185: 444.
Holt, J. A., Heise, W. F., Wilson, S. M., and Keyes, P. L., 1976, Lack of gonadotropin activity in the rabbit blastocyst prior to implantation. Endocrinology 98: 904.
Saxena, B. B., 1979, Current studies of a gonadotropin-like substance in preimplanted rabbit blastocyst, in: Recent Advances in Reproduction and Regulation of Fertility ( G. P. Talwar, ed., pp. 319–332, El- sevier/North-Holland, Amsterdam.
Saxena, B. B., and Landesman, R., 1978, Does implantation occur in the presence of an IUD?, Res. Reprod. 10: (3): 1.
Saxena, B. B., Kaali, S., and Landesman, R., 1977, The transport of chorionic gonadotropin through the reproductive tract, Eur. J. Obstet. Gynecol. 7: 1.
Singh, M. M., and Adams, C. E., 1978, Luteotropic effect of the rabbit blastocyst, J. Reprod. Fertil. 53: 331.
Sundaram, K., Connel, K. G., and Passatino, T., 1975, Implication of absence of hCG-like gonadotropin in the blastocyst for control of corpus luteum function in pregnant rabbit. Nature (London) 256: 739.
Talwar, G. P., 1978, Anti-hCG immunization. Contraception 18: 19.
Varma, S. K., Dawood, M. Y., Haour, F., Channing, C. P., and Saxena, B. B., 1979, Gonadotropin-like substance in the preimplanted rabbit blastocyst, Fertel. Steril. 31: 68.
Zielmaker, G. H., and Verhamme, C. M. P. M., 1978, Luteotropic activity of ectopically developing rat blastocysts, Endocrinol. (Copenhagen) 88: 589.
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Saxena, B.S., Asch, R.H. (1981). Presence of hCG-like Material in the Preimplantation Rabbit Blastocyst. In: Glasser, S.R., Bullock, D.W. (eds) Cellular and Molecular Aspects of Implantation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3180-3_32
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DOI: https://doi.org/10.1007/978-1-4613-3180-3_32
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