Abstract
In mammals a new genotype is formed at fertilization, but pregnancy is not established until the mother recognizes physiologically the presence of an embryo and modifies her functions to permit its survival. In general, this physiological switch in maternal function is closely correlated with the process of implantation. The mechanisms involved in the establishment of pregnancy, therefore, embrace the preimplantation and implantation periods. A physiological analysis of these periods requires the study of independent events in the embryo and mother and also interactions between these two compartments. Consequently, the contributions to this volume involve the analysis of phenomena separated in space and time.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Balfour, F. M., 1880, A Treatise on Comparative Embryology, Vol. 2, p. 220, Macmillan, London.
Biggers, J. D., 1979, Fertilization and blastocyst formation, in: Animal Models for Research on Contraception and Fertility ( N. J. Alexander, ed.), pp. 223–237, Harper Sn Row, Hagerstown, Md.
Biggers, J. D., and Borland, R. M., 1976, Physiological aspects of growth and development of the preimplantation mammalian embryo, Annu. Rev. Physiol 38: 95–119.
Biggers, J. D., and Stem, S., 1973, Metabolism of the preimplantation embryo. Adv. Reprod. Biol 6: 1–59.
Boyd, J. D., and Hamilton, W. J., 1952, Qeavage, early development and implantation of the egg, in Marshall’s Physiology of Reproduction, Vol. II ( A. S. Parkes, ed.), 3rd ed., pp. 1–126, Longmans, London.
Edwards, R. G., and Gates, A. H., 1959, Timing of the stages of maturation, divisions, ovulation, fertilization and the first cleavage of eggs of adult mice treated with gonadotropins, J. Endocrinol 18: 292–304.
Gardner, R. L., 1968, Mouse chimaeras obtained by the injection of cells into the blastocyst, Nature (London) 220: 596–597.
Hammond, J., Jr., 1949, Recovery and culture of tubal mouse ova, Nature (London) 163: 28–29.
Heape, W., 1881, On the germinal layers and early development of the mole, Proc. Roy. Soc 33: 190–198.
Heape, W., 1883, The development of the mole (Talpa europea). The formation of the germinal layers, and early development of the medullary groove and notochord. Q. J. Microsc. Sci 23: 412–452.
Heape, W., 1890, Preliminary note on the transplantation and growth of mammalian ova within a uterine foster mother, Proc. Roy. Soc 48: 457–458.
Hubrecht, A. A. W., 1888, Keimblatterbildung und Placentation des Igels, Anat. Anz 3: 510–515.
Hubrecht, A. A. W., 1889, Studies in mammalian embryology. I. The placentation of Erinaceus europoeus, with remarks on the phylogeny of the placenta, Q. J. Microsc. Sci 30: 283–404.
McLaren, A., and Biggers, J. D., 1958, Successful development and birth of mice cultivated in vitro as early embryos, Nature (London) 182: 877–878.
Mintz, B., 1962, Experimental recombination of cells in the developing mouse egg: Normal and lethal mutant genotypes, Am. Zool 2: 145 (abstract).
Rossant, J., 1977, Cell commitment in early rodent development, in: Development in Mammals, Vol. 2 ( M. H. Johnson, ed.), pp. 119–150, North-Holland, Amsterdam.
Tarkowski, A. K., 1961, Mouse chimaeras developed from fused eggs. Nature (London) 190: 857–860.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1981 Plenum Press, New York
About this chapter
Cite this chapter
Biggers, J.D. (1981). Introduction. In: Glasser, S.R., Bullock, D.W. (eds) Cellular and Molecular Aspects of Implantation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3180-3_3
Download citation
DOI: https://doi.org/10.1007/978-1-4613-3180-3_3
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-3182-7
Online ISBN: 978-1-4613-3180-3
eBook Packages: Springer Book Archive