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Ultrafiltration Membranes and Applications pp 507–521Cite as

Determination of Graetz Solution Constants in the In-Vitro Hemofiltration of Albumin, Plasma, and Blood

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Part of the book series: Polymer Science and Technology ((POLS,volume 13))

Abstract

The clinical ultrafiltration of uremic blood followed by replenishment of water and vital solutes is termed hemofiltration. The process is an alternative to dialysis for the treatment of chronic uremia and was designed to offer higher rates of clearance for intermediate molecular weight solutes (1–5). Several clinical investigators have reported both acute and chronic medical benefits for patients treated with hemofiltration rather than dialysis. These include decreased adverse symptomatology during treatment sessions (6–9) and amelioration of hypertension (10,11) and lipid mishandling (12–15) when these are secondary to uremia. The clinical evaluation of hemofiltration is continuing particularly through an NIH sponsored multicenter crossover study (16–18).

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References

  1. Colton, C.K., Henderson, L.W., Ford, C.A., and Lysaght, M.J., Kinetics of Hemodiafiltration — In-Vitro Transport Characteristics of a Hollow Fiber Blood Ultrafilter, J. Lab. Clin. Med., 85 (3), 355–371 (1975).

    CAS  Google Scholar 

  2. Henderson, L.W., Colton, C.K., and Ford, C.A., Kinetics of Hemodiafiltration, II — Clinical Characterization of a New Blood Cleansing Modality, J. Lab. Clin. Med., 85 (3), 372–391 (1975).

    CAS  Google Scholar 

  3. Lysaght, M.J., Ford, C.A., Colton, C.K., Stone, R.A., and Henderson, L.W., Mass Transfer in Clinical Blood Ultrafil¬tration Devices — A Review; Chapter in “Technical Aspects of Renal Dialysis” (T.H. Frost, Ed.), Pitman Medical Publishing Co., Ltd., United Kingdom, pp. 81–94 (1978).

    Google Scholar 

  4. Quellhorst, E., Fernandez, E., and Scheler, F., Treatment of Uremia Using an Ultrafiltration — Filtration System, Proc. Eur. Dial. & Transplant Assn., 9, 584 (1972).

    CAS  Google Scholar 

  5. Quellhorst, E., Schuenemann, B., and Doht, B., Haemofiltration —A New Method for the Treatment of Chronic Renal Insufficiency Chapter 10 in Technical Aspects of Renal Dialysis (T.H. Frost, Ed. ), Pitman Medical (1978).

    Google Scholar 

  6. Bosch, J.P., Kahn, T., Glabman, S., von Albertini, B., Geronemus R., Moutousis, G., Acid-base Homeostasis in Patients on Hemodialysis and Hemofiltration, Abstracts American Society of Nephrology, 12, 112 (1979).

    Google Scholar 

  7. Koch, K.M., Ernst, W., Baldamus, A., Brecht, M.H., George, J., Fassbinder, W., Sympathetic Activity and Hemodynamics in Hemodialysis, Ultrafiltration, and Hemofiltration, Abstracts American Society of Nephrology, 12, 121 (1979).

    Google Scholar 

  8. Shaldon, S., Deschodt, G., Bead, M.C., Claret, G., Mion, H., and Mion, E., Vascular Resistance and Stability During High Flux Hemofiltration Compared to Dialysis, Abstracts American Society of Nephrology, 12, 129 (1979).

    Google Scholar 

  9. Pierides, A.M., Schnepp, B., Johnson, W.J., Hemofiltration in the Treatment of Acute and Chronic Renal Failure, Abstracts of the 9th Annual Clinical Dialysis and Transplant Forum, 47 (1979).

    Google Scholar 

  10. Quellhorst, E., Schuenemann, B., and Doht, B., Treatment of Severe Hypertension in Chronic Renal Insufficiency by Hemofiltration, Proc. Eur. Dial. & Transplant Assn., 14 (1977).

    Google Scholar 

  11. Henderson, L.W., Ford, C.A., Lysaght, M.J., Grossman, R.A., and Silverman, M.E., Preliminary Observations on Blood Pressure Response with Maintenance Diafiltration, Kidney Int., 7, 413 (1975).

    Article  Google Scholar 

  12. San Felipo, M., Grundy, S., Henderson, L., Transport of Very Low Density Lipoprotein Triglyceride: Comparison of Hemodialysis and Hemofiltration. Abstracts 1979 American Society of Nephrology, 12, 98 (1979).

    Google Scholar 

  13. San Felippo, M., Barg, A., Henderson, L.W., Altered Lipid and Insulin Response in Hemodialysis Patients After Hemofiltration, Abstracts 1979 American Society of Nephrology, 12, 128 (1979).

    Google Scholar 

  14. San Felippo, M., Barg, A., Henderson, L.W., Altered Lipid and Insulin Response in Hemodialysis Patients After Hemofiltration, Abstracts 1979 American Society of Nephrology, 12, 128 (1979).

    Google Scholar 

  15. Henning, H.V., and Balusek, E., Lipid Metabolism in Uremia: Effect of Regular Hemofiltration and Hemodialysis Treatment, J. Dial., 1 (6), 595–605 (1977).

    CAS  Google Scholar 

  16. Quellhorst, E., Schuenemann, B., “Controlled Study to Comparing Hemodialysis and Hemofiltration. Treatment in Patients with Chronic Renal Insufficiency, 1st Annual Report on NIH NO1-AM-8-2229, 31 August 1979. Report #AK-1-8-2229-1.

    Google Scholar 

  17. Koch, K., and Baldamus, C., Hemodialysis/Hemofiltration: A Comparison of Medical Technical, and Cost Factors, 1st Annual Report on NIH Contract N01-AM-8-2227. Report #AK- 1-8-2227-1.

    Google Scholar 

  18. Bosch, J.P., Long Term Hemofiltration in Comparison with Hemodialysis, 1st Annual Report on NIH Contract N01-AM-7-2228. Report #AK-1-7-2228-1.

    Google Scholar 

  19. Kingsley, G.R., The Determination of Serum Total Protein by the Biuret Reaction, J. Biol. Chem., 131, 197–200 (1939).

    CAS  Google Scholar 

  20. Blatt, W.F., David, A., Michaels, A.S., et al: Solute Polarization and Cake Formation in Membrane Ultrafiltration: Causes, Consequences, and Control Techniques, Membrane Science and Technology, Flinn, J.E., Editor. New York, Plenum Corporation, 47–97 (1970).

    Google Scholar 

  21. Knudsen, J.G., Katz, D.L., Fluid Dynamics and Heat Transfer. New York, McGraw-Hill Book Company, 365–367 (1958).

    Google Scholar 

  22. Graetz, L., Ann. d., Physik, 337–357 (1885).

    Google Scholar 

  23. Keller, K.H., Camales, E.R., Yum, S.I., J. Phys. Chem., 75, 379 (1971).

    Article  CAS  Google Scholar 

  24. Kozinski, A.A., Ultrafiltration of Protein Solutions, PhD Thesis, Univ. of Wisconsin (1971).

    Google Scholar 

  25. Keller, K.H., Effect of Fluid Shear on Mass Transport in Flowing Blood. Fed. Proc. 30, 1591–1599 (1971).

    CAS  Google Scholar 

  26. Einstein A., Uber die von Molekular Kinetischen Theorie der Wärme Geforderte Bewegung von in Ruhenden Flüssigkeiten Suspendierten Teilchen. Ann. Phys., 17, 549–560 (1905).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Biomedical Products Division, Amicon Corporation, Lexington, Mass., 02173, USA

    Kenneth Isaacson, Patricia Duenas, Cheryl Ford & Michael Lysaght

Authors
  1. Kenneth Isaacson
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  2. Patricia Duenas
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  3. Cheryl Ford
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  4. Michael Lysaght
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Editor information

Editors and Affiliations

  1. Dynapol, Palo Alto, California, USA

    Anthony R. Cooper

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© 1980 Plenum Press, New York

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Isaacson, K., Duenas, P., Ford, C., Lysaght, M. (1980). Determination of Graetz Solution Constants in the In-Vitro Hemofiltration of Albumin, Plasma, and Blood. In: Cooper, A.R. (eds) Ultrafiltration Membranes and Applications. Polymer Science and Technology, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3162-9_36

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  • DOI: https://doi.org/10.1007/978-1-4613-3162-9_36

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3164-3

  • Online ISBN: 978-1-4613-3162-9

  • eBook Packages: Springer Book Archive

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