Abstract
The Golden Syrian hamster has served as a model for antibiotic-associated colitis of humans and has been instrumental in discovering its pathogenesis (4,18). Toxigenic Clostridium difficile have been implicated as the major cause of antibiotic-associated colitis (AAC) in both hamsters and humans (5,10,20). While clindamycin first focused attention on this lesion, many other antibiotics have been implicated subsequently following either parenteral or oral administrations. AAC also varies greatly in its clinical presentation in humans and in its geographic distribution (17,23).
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© 1980 Plenum Press, New York
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Silva, J. et al. (1980). Immune Responses of Hamsters and Humans with Antibiotic-Associated Colitis. In: Lambe, D.W., Genco, R.J., Mayberry-Carson, K.J. (eds) Anaerobic Bacteria. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3159-9_21
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