Abstract
According to present knowledge transfer of bivalent or sulphane sulphur from thiosulphate, thiocystine, 3-mercaptopyruvate and some other donors is catalyzed by at least three different enzymes: rhodanese /EC 2.8. 1.1/, thiosulphate reductase /no EC number/ and mercapto-pyruvate sulphurtransferase /EC 2.8.1.2/ /for references see Westley, 1973; Koj et al.,1975/. The mechanism of their action is not uniform: rhodanese operates by a double-displacement mechanism /cf. Westley, 1973/ mercaptopyruvate sulphurtransferase by a sequential reaction /Jarabak and Westley,1978/, while the mode of action of thiosulphate reductase is not elucidated.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Auriga,M., and Koj, A., 1975, Protective effect of rhodanese on the respiration of isolated mitochondria intoxicated with cyanide, Bull.Acad.Pol. Sci., Ser.Sci.Biol. 23: 305.
Bonomi, F., Pagani, S., Cerletti, P., Cannella C., 1977, Rhodanes-mediated sulfur transfer to succinate dehydrogenase, Eur,J,Biochem., 72: 17
Crompton, M., Palmieri, F., Capano, M., and Quaglia- riello, E., 1974, The transport of thiosulphate in rat liver mitochondria, FEBS Lett, 46: 247.
DeDuve, C., Pressman, B.C., Gianetto, R., Wattiaux, R., and Appelmans, F., 1955 Tissue fractionation studies. Intracellular distribution patterns of enzymes in rat liver tissues, Biochem.J., 60: 604.
Dudek, M., Frendo, J., and Koj, A,, 1979, Subcellular compartmentation of rhodanese and 3-morcaptopyru- vate sulphurtransferase in the liver of some vertebrate species, Comp.Biochem.Physiol.
Finazzi-Agro, A., Cannella, C., Graziani, M.T., and Cavallini, D., 1971, A possible role for rhodanese: the formation of “labile” sulphur from thiosulphate FEBS Lett., 16: 172.
Jarabak, R., and J. Vestley, 1978, Steady state kinetics of 3-m©rcaptopyruvate sulphurtransferase from bovine kidney, Arch.Bioch.Bioph., 185: 458.
Kasperczyk, H., Koj, A., and Z. Wasylewski, 1977, Similarity of some molecular and catalytic parameters of mitochondrial and cytosolic mercapto- pyruvate sulphurtransferase from rat liver, Bull. Acad, Pol.Sci.,Ser.Sci.Biol., 25: 7.
Koj, A., and Ffendo, J., 1967, Oxidation of thiosulphate to sulphate in animal tissues, Folia Biol./Krakow/, 15: 49.
Koj, A., Frendo, J., and Wojtczak, L., 1975, Subcellular distribution and intramitochondrial localization of three sulphurtransferases in rat liver, FEBS Lett., 57: 42.
Koj, A., Michalik, M., and Kasperczyk, H., 1977, Mito-chondrial and cytosol activities of three sulphur-transferases in some rat tissues and Morris hepatomas, Bull.Acad.Pol.Sci tSer.Sci.Biol. 25: 1
Marra, E., Boonan, S., Saccone, C., and Quagliariello, E., 1978, Studies on the selective permeation of radioactivelly labelled aspartate aminotransferase isozymes into mitochondria in vitro, Eur.J.Bio chem. 83: 427.
Schatz, G, and Mason, T.L., 1974, The biosynthesis of mitochondrial proteins, Ann.Rev.Biochem.: 51
Schievelbein, H., Baumeister, R., and Vogel, R., 1969, Comparative investigations on the activity of thiosulphate sulphurtransferase, Naturvissenschaf- ten,56:4l6.
Sörbo, B., 1957 Sulphite and complex-bound cyanide as sulphur acceptors for rhodanese, Acta Chem. Scand., 11: 628.
Szczepkowski, T.W., and Wood, J.L., 1967, The cystathio- naserhodanese system, Biochim. Biophys. Acta, 139: 469.
Taniguchi, T., and Kimura, T., 1974, Role of 3-mercapto- pyruvate sulphurtransferase in the formation of the iron-sulphur chromophore of adrenal ferredoxin, Biochim. Biophys.Acta, 364: 284.
Volini, M, Craven, D., and Ogata, K., 1977 Rhodanese iron protein association in bovine liver extracts, Biochem. Biophys.Res.Comm., 79: 890.
Westley, J., 1973 Rhodanese, Adv.Enzymol., 39: 327
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1980 Plenum Press, New York
About this chapter
Cite this chapter
Koj, A. (1980). Subcellular Compartmentation and Biological Functions of Mercaptopyruvate Sulphurtransferase and Rhodanese. In: Cavallini, D., Gaull, G.E., Zappia, V. (eds) Natural Sulfur Compounds. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3045-5_45
Download citation
DOI: https://doi.org/10.1007/978-1-4613-3045-5_45
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-3047-9
Online ISBN: 978-1-4613-3045-5
eBook Packages: Springer Book Archive