On the Mechanism of C-S Bonds Formation in the Biosynthesis of Biotin

  • Andrée Marquet
  • Adel Guirguis Salib
  • François Frappier
  • Georges Guillerm

Abstract

The biosynthesis of biotin, 1, has already been intensively studied (1). All the intermediates in the biosynthetic pathway from pimelic acid to dethiobiotin, 2, are presently known and formed by classical biochemical reactions. But the mechanism of the conversion of dethiobiotin into biotin, a very unusual transformation, is still completely unknown.

Keywords

Permeability Aldehyde Carbonyl Biotin Alco 

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Andrée Marquet
    • 1
  • Adel Guirguis Salib
    • 2
  • François Frappier
    • 1
  • Georges Guillerm
    • 1
  1. 1.Laboratoire de Chimie Organique BiologiqueTour 44-45, Université P. et M. CurieParis Cedex 05France
  2. 2.Biochemistry Department - Faculty of AgricultureZagazig UniversityZagazigEgypt

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