Metabolism of Hypotaurine in Some Organs of the Rat
Although various physiological roles were suggested for taurine in different tissues like brain, heart, retina, the origin of this substance in these tissues is still unclear. Taurine could be provided by the diet and could also be synthesized. Until now, three main pathways were described or postulated in mammals for this biosynthesis 1:
the “inorganic pathway” untilizing inorganic sulfate,
the “cysteamine pathway”,
the “cysteine sulfinic pathway”.
KeywordsSucrose Cysteine Retina Cytosol Taurine
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- 2.R.J. Huxtable, Regulation of Taurine in the Heart in Taurine and Neurological Disorders, A. Barbeau and R.J. Huxtable, ed., Raven Press, New York (1978).Google Scholar
- 3.J. Awapara, The Metabolism of Taurine in the Animal, in Taurine,R.J.Huxtable and A. Barbeau, éd., Raven Press, New York (1976).Google Scholar
- 5.F. Chatagner and B. Bergeret, Décarboxylation enzy- matique in vivo et in vitro de l’acide cystéine suifinique dans le foie des animaux supérieurs, C.R. Acad. Sci. 232: 448 (1951).Google Scholar
- 8.R.M. Di Giorgio, G. De Luca and S. Macaione, Hypo-taurine Oxidase Activity in Retina, Bull. Mol. Biol. and Med. 3: 115 (1978).Google Scholar
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