Abstract
Orgotein, the generic name for drug versions of Cu-Zn superoxide dismutases (SOD), is a new anti-inflammatory drug (1) which has been shown to be very safe in man and animals (2). In veterinary medicine orgotein has been used for some years in the treatment of arthritis and cataracts. Cu-Zn SODs are stable, soluble metalloproteins whose MW is approximately 32,000. They are found intracellularly in liver, kidney, red cells and other tissues in varying amounts (3). Both the amino acid sequence and the structural features of the protein have been determined and the essential features of the molecule are well understood (4,5).
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References
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© 1980 Plenum Press, New York
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Edsmyr, F., Menander-Huber, K.B., Huber, W. (1980). Orgotein Efficacy in Ameliorating Side Effects Due to Radiation Therapy. In: Pavone-Macaluso, M., Smith, P.H., Edsmyr, F. (eds) Bladder Tumors and other Topics in Urological Oncology. Ettore Majorana International Science Series, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3030-1_5
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DOI: https://doi.org/10.1007/978-1-4613-3030-1_5
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