Effects of Intravesical Formaldehyde-Instillation (Experimental and Clinical Results)

  • R Pust
  • A Rost
Part of the Ettore Majorana International Science Series book series (EMISS, volume 1)


Changes in the urinary bladder wall following intravesical instillation of 5 – 25% formalin were studied in 25 healthy female cats. The contact period varied from one to 20 minutes. With a 20% solution and one minute contact time the bladder urothelium proteins quickly precipitated without necrosis of sub-epithelial layers. Complete re-epithelialisation and normal bladder dynamics (x-ray control) were seen after three to four weeks.

No signs of formaldehyde intoxication were observed. In four of five patients with intractable bleeding of the bladder the intravesical formaldehyde therapy was effective.


Muscular Layer Formaldehyde Solution Ureteral Obstruction Bladder Mucosa Intravesical Instillation 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • R Pust
    • 1
  • A Rost
    • 2
  1. 1.Department of Urology, Klinikum GiessenJ. L.-University GiessenGermany
  2. 2.Department of Urology, Klinikum SteglitzFree University of BerlinGermany

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