Skip to main content

Adaptation of Respiratory Mass Spectrometer to Continuous Recording of Abundance Ratios of Stable Oxygen Isotopes

  • Chapter
Book cover Recent Developments in Mass Spectrometry in Biochemistry and Medicine

Abstract

Respiratory mass spectrometers have been developed for a continuous determination of several gas components in inspiratory and expiratory air. The first generation of this kind of mass spectrometers is represented by the type M3 of Varian MAT (Fig. 1). It is a mass spectrometer with a 180° magnetic sector having four collectors to determine four different components of a gas mixture simultaneously. Its sensitivity is 10 ppm and its resolution about 25. For some years a second generation of respiratory mass spectrometers with magnetic deflection has been available. They represent an improvement in their stability of measurement and operating conditions but are of decreased sensitivity. Some mass spectrometers of the quadrupole type have a sensitivity up to 0.2 ppm but there may arise problems in measuring two components with very different abundances simultaneously. Respiratory mass spectrometers are well suitable to analyse the major components of air but they are not suitable for the measurement of isotopic abundance.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. W.W. Shreeve, in “Proceedings Third International Conference on Stable Isotopes in Chemistry, Biology and Medicine”, May 23–26, Argonne National Laboratory, Argonne, Illinois, 1978.

    Google Scholar 

  2. H. Helge, B. Gregg, E. Jager, G. Borchert and S. Nigam, in “Proceedings Third International Conference on Stable Isotopes in Chemistry, Biology and Medicine”, May 23–26, Argonne National Laboratory, Argonne, Illinois, 1978.

    Google Scholar 

  3. J.F. Schneider, D.L. Hachey, B.B. Schreider, A.N. Kotake, D.A. Schoeller and P.D. Klein, in “Proceedings Third International Conference on Stable Isotopes in Chemistry, Biology and Medicine”, May 23–26, Argonne National Laboratory, Argonne, Illinois, 1978.

    Google Scholar 

  4. Y. Sasaki, H. Oh-hara, S. Takahashi, K. Someya and K. Sano, in “Proceedings Third International Conference on Stable Isotopes in Chemistry, Biology and Medicine”, May 23–26, Argonne National Laboratory, Argonne, Illinois, 1978.

    Google Scholar 

  5. R. Park, J.B. Watkins, J. Perman and D.S. Schoeller, in “Proceedings Third International Conference on Stable Isotopes in Chemistry, Biology and Medicine”, May 23–26, Argonne National Laboratory, Argonne, Illinois, 1978.

    Google Scholar 

  6. K.D. Schuster, K.P. Pflug, H. Forstel and J.P. Pichotka, in “Proceedings Third International Conference on Stable Isotopes in Chemistry, Biology and Medicine”, May 23–26, Argonne National Laboratory, Argonne, Illinois, 1978.

    Google Scholar 

  7. K.P. Pflug, K.D. Schuster, H. Forstel and J.P. Pichotka, Biomed. Technick., Aachen 1977.

    Google Scholar 

  8. J.H. Beynon, in “Mass spectrometry and its application to organic chemistry”, Elsevier, Amsterdam, 1960, p. 52.

    Google Scholar 

  9. J. Blears and A.K. Mettrick, in “Proceedings Xlth International Congress Pure and Applied Chemistry”, Vol. 1, 1947, p. 333.

    Google Scholar 

  10. C. Brunnee and H. Voshage, “Massenspektrometrie”, Verlag Karl Thiemig KG, München, 1964, p. 112.

    Google Scholar 

  11. J. Duchesne and A. van de Vorst, Acad. Sei, Ser. D, 1968, 266, 522.

    Google Scholar 

  12. B.S. Jacobsen, B.N. Smith and A.V. Jacobsen, Biochem. Biophys. Res. Commun., 1972, 45, 398.

    Article  Google Scholar 

  13. A.O. Nier, E.P. Ney and M.G. Inghram, Rev. Sei. Instr., 1947, 18, 294.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1979 Plenum Press, New York

About this chapter

Cite this chapter

Schuster, KD., Pflug, KP., Förstel, H., Pichotka, J.P. (1979). Adaptation of Respiratory Mass Spectrometer to Continuous Recording of Abundance Ratios of Stable Oxygen Isotopes. In: Frigerio, A. (eds) Recent Developments in Mass Spectrometry in Biochemistry and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3018-9_34

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-3018-9_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3020-2

  • Online ISBN: 978-1-4613-3018-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics