Gas Chromatographic-Mass Spectrometric Identification of Urinary Metabolites of Propildazine in Rat

  • L. Simonotti
  • R. Colombo
  • G. Pifferi


Propildazine (ISF 2123) is a new antihypertensive drug selected among a series of 6-substituted 3-hydrazinopyridazines synthesized in our laboratories (1–3) (Fig. 1).


Urinary Metabolite Amino Alcohol Derivative Versus Charge Retention Silyl Derivative 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • L. Simonotti
    • 1
  • R. Colombo
    • 1
  • G. Pifferi
    • 1
  1. 1.I.S.F. - Italseber Research LaboratoriesTrezzano s/N, MilanoItaly

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