Medical Application of Neutron Capture γ-Ray Spectroscopy: Measurement of Cadmium and Nitrogen in Living Human Subjects

  • D. Vartsky
  • K. J. Ellis
  • S. H. Cohn

Abstract

A significant environmental-medical problem is the internal deposition of cadmium in man. Cadmium is absorbed by human beings via inhalation of polluted air or ingestion of contaminated food and water. Absorbed cadmium is concentrated in the liver and kidneys. The “Standard American Man” has been reported to contain approximately 30–50 mg of Cd in the whole body of which about one- half is in the kidneys and the liver together. The small quantity of cadmium found in the human newborn (<1µg) as contrasted with the accumulation with age lead to the hypothesis that certain chronic diseases could be the result of Cd toxicity. Cd has been suggested as a possible causative agent of hypertension, emphysema, renal disfunction and osteomalacia. In-vivo measure of the liver and kidney Cd provides a direct index of Cd exposure and can help in the determination of dose-effect relationships.

Keywords

Toxicity Cadmium Epoxy Osteomalacia 

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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • D. Vartsky
    • 1
  • K. J. Ellis
    • 1
  • S. H. Cohn
    • 1
  1. 1.Brookhaven National LaboratoryMedical Research CenterUptonUSA

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