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Psychological Effects of Cholinomimetic Agents

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Brain Acetylcholine and Neuropsychiatric Disease

Abstract

Janowsky, Davis and colleagues began in 1972 to explore the possibility that the affective disorders, mania and depression, might be due to a complex balance, or inter-action, between adrenergic and cholinergic factors (Janowsky et al., 1972a). Proposed most simply, mania was hypothesized to be a syndrome due to relatively diminished central acetylcholine (ACh) activity, compared to normal or increased noradrenergic and/or dopaminergic activity; and depression was proposed to be the converse (Janowsky et al., 1972b).

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Author information

Authors and Affiliations

  1. Department of Psychiatry, University of California at San Diego, School of Medicine, La Jolla, California, 92093, USA

    D. S. Janowsky & J. M. Davis

Authors
  1. D. S. Janowsky
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  2. J. M. Davis
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Editor information

Editors and Affiliations

  1. Veterans Administration Hospital, Palo Alto, California, 94304, USA

    Kenneth L. Davis  & Philip A. Berger  & 

  2. Stanford University School of Medicine, Stanford, California, 94305, USA

    Kenneth L. Davis  & Philip A. Berger  & 

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© 1979 Plenum Press, New York

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Janowsky, D.S., Davis, J.M. (1979). Psychological Effects of Cholinomimetic Agents. In: Davis, K.L., Berger, P.A. (eds) Brain Acetylcholine and Neuropsychiatric Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2934-3_1

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  • DOI: https://doi.org/10.1007/978-1-4613-2934-3_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-2936-7

  • Online ISBN: 978-1-4613-2934-3

  • eBook Packages: Springer Book Archive

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