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Approach to the pituitary tumor: anatomic, diagnostic and surgical considerations

  • Chapter
Diagnosis and Management of Endocrine-related Tumors

Part of the book series: Cancer Treatment and Research ((CTAR,volume 20))

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Abstract

Patients harboring putative pituitary tumors reach neurosurgeons through three lines of referral. Neurologists refer patients with symptoms and signs of intracranial mass such as dulled affect, lethargy, hemiparesis, seizures or failing vision [1]. Their goal of therapy is total removal of the intracranial mass which has arisen from the sellar region and restoration of brain function. Ophthalmologists refer patients with specific visual disturbances. Their goal is decompression of the visual or oculo-motor pathways with restoration of normal vision [2]. Endocrinologists refer patients with symptoms and signs of endocrine dysfunction. These may be manifestations of pituitary hypofunction with gonadal, adrenal, and/or thyroid underactivity or even, in the case of children, failure to grow at a normal rate [1,2]. Endocrine abnormalities may also be caused by hyperfunction of adenomatous pituitary tissue with oversecretion of prolactin (PRL) [3,4,5], of luteinizing hormone (LH) [6, 7], or of follicle stimulating hormone (FSH) [8, 9] causing inferility, of growth hormone (GH) causing acromegaly [10, 11, 12], of adrenocorticotrophic hormone (ACTH) causing Cushing’s disease [13,14] or of thyroid stimulating hormone (TSH) causing hyperthyroidism [15,16]. The endocrinologists’ goal is complete tumor removal and restoration of pituitary function.

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Authors
  1. Robert B. Page
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  2. Richard J. Santen
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Editors and Affiliations

  1. Division of Endocrinology, The Milton S. Hershey Medical Center, The Pennsylvania State University, 17033, P.O. Box 850, Hershey, PA, USA

    Richard J. Santen M.D. (Professor of Medicine, Chief) & Andrea Manni M.D. (Associate Professor of Medicine) (Professor of Medicine, Chief) &  (Associate Professor of Medicine)

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© 1984 Martinus Nijhoff Publishers, Boston

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Page, R.B., Santen, R.J. (1984). Approach to the pituitary tumor: anatomic, diagnostic and surgical considerations. In: Santen, R.J., Manni, A. (eds) Diagnosis and Management of Endocrine-related Tumors. Cancer Treatment and Research, vol 20. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2849-0_1

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