Abstract
A discussion of the pathology of pulmonary heart disease must be centered on the pulmonary vasculature since, in the disease processes relevant to this chapter, the heart is an innocent bystander to events taking place in the lungs. Frequently, the cardiac changes are important and in many cases may constitute the dominant clinical findings. But, the lungs, and the pulmonary vasculature in particular, are where the most prominent pathologic changes usually reside. These changes may be intrinsic to the lung, such as in primary pulmonary hypertension, or secondary to abnormalities in other parts of the body, as in peripheral venous thrombosis with pulmonary thromboembolic disease. Exceptions to this generalization might be congenital heart disease or ischemic heart disease with chronic left ventricular failure, in which the main problem is intrinsic to the heart. These conditions may undoubtedly be associated with pulmonary vascular overload, right ventricular hypertrophy, and right ventricular failure; however, these intrinsic cardiac problems are not ordinarily included in definitions of pulmonary heart disease, or, as it is more commonly known, cor pulmonale (1).
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Taylor, W.E. (1984). Pathology of Pulmonary Heart Disease. In: Rubin, L.J. (eds) Pulmonary Heart Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2847-6_3
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