Abstract
Carcinoma of the oral cavity may be associated with or preceded by lesions that carry a serious risk of malignant changes. These so-called precancerous lesions may precede the development of carcinoma by months or by years. The WHO has defined a precancerous lesion as “a morphologically altered tissue in which cancer is more likely to occur than in its apparently normal counterpart,” whereas a premalignant condition is defined as “a generalized state associated with a significantly increased risk of cancer” [1]. According to the present viewpoints, the following pathological lesions and conditions are considered premalignant: leukoplakia, erythroplakia, and submucous fibrosis.
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Bánóczy, J. (1984). Clinical and Histopathological Aspects of Premalignant Lesions. In: van der Waal, I., Snow, G.B. (eds) Oral Oncology. Developments in Oncology, vol 20. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2845-2_1
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