Skip to main content

Role of Conservative Surgery for Patients with Bilateral Kidney Tumors

  • Chapter
Urologic Oncology

Part of the book series: Cancer Treatment and Research ((CTAR,volume 19))

Abstract

Renal cell carcinoma or renal adenocarcinoma originates in the malignant transformation of renal tubular epithelial cells. The cause of the malignant transformation is unknown. There is evidence that environmental carcinogens may be involved [1], but the incidence of renal cancer appears to be stable. Renal adenocarcinoma affects adults with an increasing incidence with age. Most series show the mean age of disease appearance in the late sixth decade and males to be affected more commonly than females. Young adults aged 20–40 develop renal adenocarcinoma less commonly, but the behavior of the cancer in young adults is essentially the same as in older adults [2].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kantor AF: Current concepts in the epidemiology and etiology of primary renal cell carcinoma. J Urol 117:415–417, 1977.

    PubMed  CAS  Google Scholar 

  2. Lieber MM, Tomera FM, Taylor WF, Farrow GM: Renal adenocarcinoma in young adults: Survival and variable affecting prognosis. J Urol 125:164–168, 1981.

    PubMed  CAS  Google Scholar 

  3. Malek RS, Greene LF: Urologic aspects of Hippel-Lindau syndrome. J Urol 106:800–801, 1971.

    PubMed  CAS  Google Scholar 

  4. Goldman SM, Fishman EK, Abeshouse G, Cohen JH: Renal cell carcinoma diagnosed in three generations of a single family. South Med J 72:1457–1459, 1979.

    Article  PubMed  CAS  Google Scholar 

  5. Pathek S, Strong LC, Ferrell RE, Trindade A: Familial renal cell carcinoma with a 3:11 chromosome translocation limited to tumor cells. Science 217:939–941, 1982.

    Article  Google Scholar 

  6. Cohen AJ, Li FP, Berg SI, Marchetto DM, Tsai S, Jacobs SC, Brown RS: Hereditary renalcell carcinoma associated with a chromosomal translocation. N Engl J Med 301:592–595, 1979.

    Article  PubMed  CAS  Google Scholar 

  7. Franksson C, Berstrand A, Ljungdahl I, Magnusson H, Nordenstrom H: Renal carcinoma (hypernephroma) occurring in 5 siblings. J Urol 108:58–61, 1972.

    PubMed  CAS  Google Scholar 

  8. Krumbach RW, Ansell JS: Partial resection of the right kidney and radical removal of the left kidney in a patient with bilateral hypernephroma. Surgery 45:585–592, 1959.

    Google Scholar 

  9. Marberger M, Pugh RCB, Auvert J, Bertermann H, Constantini A, Gammelgaard PA, Petterson S, Wickham JEA: Conservative surgery of renal carcinoma: The EIRSS experience. Br J Urol 53:528–532, 1981.

    Article  PubMed  CAS  Google Scholar 

  10. Berg S, Jacobs SC, Cohen AJ, Li L, Marchetto D, Brown RS: The surgical management of hereditary multifocal renal carcinoma. J Urol 126:313–315, 1981.

    PubMed  CAS  Google Scholar 

  11. Knudson AG Jr: Mutation and human cancer. Adv Cancer Res 17:317–352, 1973.

    Article  Google Scholar 

  12. Vermillion CD, Skinner DG, Pfister RC: Bilateral renal carcinoma. J Urol 108:219–222, 1972.

    PubMed  CAS  Google Scholar 

  13. Saitoh H, Hida M, Nakamura K, Shimbo T, Shiramizu T, Satoh T: Metastatic processes and a potential indication of treatment for metastatic renal adenocarcinoma. J Urol 128:916–918, 1982.

    PubMed  CAS  Google Scholar 

  14. DeKernion JB, Ramming KP, Smith RB: The natural history of metastatic renal cell carcinoma: A computer analysis. J Urol 120:148–152, 1978.

    PubMed  CAS  Google Scholar 

  15. Jacobs SC, Berg SI, Lawson RK: Synchronous bilateral renal cell carcinoma: Total surgical excision. Cancer 46:2341–2345, 1980.

    Article  PubMed  CAS  Google Scholar 

  16. Zincke H, Swanson SK: Bilateral renal cell carcinoma: Influence of synchronous and asynchronous occurrence on patient survival. J Urol 128:913–915, 1982.

    PubMed  CAS  Google Scholar 

  17. Vermooten V: Indications for conservative surgery in certain renal tumors: A study based on a growth pattern of the clear cell carcinoma. J Urol 64:200–208, 1950.

    PubMed  CAS  Google Scholar 

  18. Rafla S: Renal cell carcinoma. Natural history and results of treatment. Cancer 25:26, 1970.

    Article  PubMed  CAS  Google Scholar 

  19. Patel NP, Lavengood RN: Renal cell carcinoma: Natural history and results of treatment. J Urol 119:722–726, 1978.

    PubMed  CAS  Google Scholar 

  20. Priestly JT: Survival following removal of malignant renal neoplasms. JAMA 113:902–906, 1939.

    Google Scholar 

  21. Boxer RJ, Waisman J, Lieber MM, Mampaso FM, Skinner DG: Renal carcinoma: Computer analysis of 96 patients treated by nephrectomy. J Urol 122:598–601, 1979.

    PubMed  CAS  Google Scholar 

  22. Robson CJ, Churchill BM, Anderson W: The results of radical nephrectomy for renal cell carcinoma. J Urol 101:297–301, 1969.

    PubMed  CAS  Google Scholar 

  23. Waters WB, Richie JP: Aggressive surgical approach to renal cell carcinoma: Review of 130 cases. J Urol 122:306, 1979.

    PubMed  CAS  Google Scholar 

  24. Siminovitch JO, Montie JE, Straffon RA: Lyphadenectomy in renal adenocarcinoma. J Urol 127:1090, 1982.

    PubMed  CAS  Google Scholar 

  25. Robson CJ: Radical nephrectomy for renal cell carcinoma. J Urol 89:37–42, 1963.

    PubMed  CAS  Google Scholar 

  26. Mintz ER: Renal cancer. End results in 105 consecutive cases. N Engl J Med 218:329–337, 1938.

    Article  Google Scholar 

  27. Humphreys GA, Foot NC: Survival of patients (235) following nephrectomy for renal cell and transitional cell tumors of the kidney. J Urol 83:815–819, 1960.

    PubMed  CAS  Google Scholar 

  28. Rubin P: Current concepts in genitourinary oncology: A multidisciplinary approach. J Urol 106:315–338, 1971.

    PubMed  CAS  Google Scholar 

  29. Bergendal S: To the clinical study and prognosis of tumours of the kidney. Acta Chir Scandinav 77:563–625, 1936.

    Google Scholar 

  30. Hunt VC, Hager BH: A review of 271 cases of malignant renal neoplasms. Surg Clin North Am 9:149–159, 1929.

    Google Scholar 

  31. Schiff M Jr, Glazier WB: Nephrectomy: Indications and complications in 347 patients. J Urol 118:930–931, 1977.

    PubMed  Google Scholar 

  32. Soloway HM: Renal tumors. A review of one hundred thirty cases. J Urol 40:477–490. 1938.

    Google Scholar 

  33. Bryan FA: Sixth annual report. The National dialysis registry, Research triangle institute report no. AK-5–67–1387: Cancer, facts and figures, October, 1974.

    Google Scholar 

  34. Evans DB, Calne RY: Renal transplantation in patients with carcinoma. Br Med J 4:134–136, 1974.

    Article  PubMed  CAS  Google Scholar 

  35. Spees EK, Light JA, Smith EJ, Mostofi FK, Oakes DD: Transplantation in patients with a history of renal cell carcinoma: Long-term results and clinical considerations. Surgery 91:282–287, 1982.

    PubMed  CAS  Google Scholar 

  36. Penn I: Transplantation in patients with primary renal malignancies. Transplantation 24:424–434, 1977.

    Article  PubMed  CAS  Google Scholar 

  37. Lowsley OS: Modern renal surgery with particular reference to heminephrectomy. NY State J Med 36:591–601, 1936.

    Google Scholar 

  38. Montie JE: Management of stage I, II and III renal adenocarcinoma. In: Principles and management of urologic cancer. Javadpour N (ed). Baltimore: Williams and Wilkins, 2nd ed, pp 00–00, 1983 (in press).

    Google Scholar 

  39. Klein TW, Lamm D, Gittes RF: Renal autotransplantation: Influence of contralateral nephrectomy on the damaging effect of warm ischemia during transplantation. Invest Urol 15:256–261, 1977.

    PubMed  CAS  Google Scholar 

  40. Marberger M, Stackl W: Renal hypothermia in situ. In: Current trends in urology (Resnick MI (ed). Baltimore: Williams & Wilkins, pp 70–89, 1981.

    Google Scholar 

  41. Gibbons RP, Correa RJ Jr, Cummings KB, Mason JT: Surgical management or renal lesions using in situ hypothermia and ischemia. J Urol 115:12–17, 1976.

    PubMed  CAS  Google Scholar 

  42. Novick AC, Stewart BH, Straffon RA, Banowsky LH: Partial nephrectomy in the treatment of renal adenocarcinoma. J Urol 118:932, 1977.

    PubMed  CAS  Google Scholar 

  43. Beraha D, Block NL, Politano VA: Simultaneous surgical management of bilateral hypernephroma: An alternative therapy. J Urol 115:648–650, 1976.

    PubMed  CAS  Google Scholar 

  44. Graham SD Jr, Glenn JF: Enucleative surgery for renal malignancy. J Urol 122:546–549, 1979.

    PubMed  Google Scholar 

  45. Pearson JC, Weiss J, Tangho EA: A plea for conservation of kidney in renal adenocarcinoma associated with Von Hippel-Lindau disease. J Urol 124:910–912, 1980.

    PubMed  CAS  Google Scholar 

  46. Calne RY: Tumour in a single kidney: Nephrectomy, excision and autotransplantation. Lancet 2:761–762, 1971.

    Article  PubMed  CAS  Google Scholar 

  47. Lawson RK: Extracorporeal renal surgery. J Urol 123:301–305, 1980.

    PubMed  CAS  Google Scholar 

  48. Stewart BH, Banowsky LH, Hewitt CB, Straffon RA: Renal autotransplantation: Current perspectives. J Urol 118:363–368, 1977.

    PubMed  CAS  Google Scholar 

  49. Gittes RF, McCullough DL: Bench surgery for tumor in a solitary kidney. J Urol 113:12–15, 1975.

    PubMed  CAS  Google Scholar 

  50. Corman JL, Girard R, Fiala M, Gallot D, Stonington O, Stables DP, Taubman J, Starzl TE: Arteriography during ex vivo renal perfusion. Urology 2:222–226.

    Google Scholar 

  51. Novick AC: Extracorporeal renal surgery and autotransplantation. In: Vascular Problems in Urologic surgery, Novick AC, Straffon RA (eds). Philadelphia: WB Saunders Company, pp 305–328, 1981.

    Google Scholar 

  52. Palmer JM, Swanson DA: Conservative surgery in solitary and bilateral renal carcinoma: Indications and technical considerations. J Urol 120:113–117, 1978.

    PubMed  CAS  Google Scholar 

  53. Gittes RF, Blute RD Jr: Repeat bench surgery on a solitary kidney. J Urol 127:530–532, 1982.

    PubMed  CAS  Google Scholar 

  54. Gelin LE: Extracorporeal surgery for renal problems. Surg Ann 9:351–379, 1977.

    CAS  Google Scholar 

  55. Lawson RK, Hodges CV: Extracorporeal renal artery repair and autotransplantation. Urology 4:532–539, 1974.

    Article  PubMed  CAS  Google Scholar 

  56. Whitsell JC III, Goldsmith EI, Nakamura H: Renal autotransplantation without ureteral division: An experimental study and case report. J Urol 103:577–582, 1970.

    PubMed  Google Scholar 

References

  1. Margerber M, Pugh RCB, Auvert J, Betermann H, Costantini A, Gammelgaard PA, Petterson S, Wickham JEA: Conservative surgery of renal carcinoma: the EIRSS experience. Br J Urol 53:528, 1981.

    Article  Google Scholar 

  2. Zincke H, Swanson SK: Bilateral renal cell carcinoma: Influence of synchronous and asynchronous occurrence on patient survival. J Urol 128:913, 1982.

    PubMed  CAS  Google Scholar 

  3. Topley M. Novick AC, Montie JE: Long-term results following partial nephrectomy for localized renal adenocarcinoma (in press).

    Google Scholar 

  4. Jacobs SC, Berg SI, Lawson RK: Synchronous bilateral renal cell carcinoma: Total surgical excision. Cancer 46:2341, 1980.

    Article  PubMed  CAS  Google Scholar 

  5. Vermooten V: Indications for conservative surgery in certain renal tumors: A study based on the growth pattern of the clear cell carcinoma. J Urol 64:200, 1950.

    PubMed  CAS  Google Scholar 

  6. Gittes RF, Blute RD: Repeat bench surgery on a solitary kidney. J Urol 127:530, 1982.

    PubMed  CAS  Google Scholar 

  7. Novick AC, Stewart BH, Straffon RA, Banowsky LH: Partial nephrectomy in the treatment of renal adenocarcinoma. J Urol 118:932, 1977.

    PubMed  CAS  Google Scholar 

  8. Graham SD, Glenn JF: Enucleative surgery for renal malignancy. J Urol 122:546, 1979.

    PubMed  Google Scholar 

  9. Pearson JC, Weiss J, Tanagho EA: A plea for conservation of kidney in renal adenocarcinoma associated with von Hippel-Landau disease. J Urol 124:910, 1980.

    PubMed  CAS  Google Scholar 

  10. Novick AC, Magnusson MO: Extracorporeal and in situ renal preservation. In: Vascular problems in Urologic surgery, Novick AC, Straffon RA (ed). Philadelphia: WB Saunders Company, 1982.

    Google Scholar 

  11. Farcon EM, Morales P, Al-Askari S: In vivo hypothermic perfusion during renal surgery. Urology 3:414, 1974.

    Article  PubMed  CAS  Google Scholar 

  12. Marberger M, Georgi M, Guenther R, Hohenfellner R: Simultaneous balloon occlusion of the renal artery and hypothermic perfusion in in-situ surgery of the kidney. J Urol 119:463, 1978.

    PubMed  CAS  Google Scholar 

  13. Novick AC: Extracorporeal renal surgery and autotransplantation. In: Vascular problems in Urologic surgery, Novick AC, Straffon RA (ed). Philadelphia: WB Saunders Company, 1982.

    Google Scholar 

  14. Novick AC, Magnusson M, Braun WE: Multiple-artery renal transplantation: Emphasis on extracorporeal methods of donor arterial reconstruction. J Urol 122:731, 1979.

    PubMed  CAS  Google Scholar 

  15. Penn I: Transplantation in patients with primary renal malignancies. Transplantation 24:424, 1977.

    Article  PubMed  CAS  Google Scholar 

  16. Paganini EP, Vidt DG: Renal replacement therapy utilizing hemodialysis and peritoneal dialysis. Urol Clin North Am 10:347, 1982.

    Google Scholar 

  17. Banowsky LHW: Current results and future expectations in renal transplantation. Urol Clin North Am 10:337, 1983.

    PubMed  CAS  Google Scholar 

  18. Novick AC, Streem SB, Braun WE, Steinmuller D, Goormastic M, Cunningham R: Prophylactic antilymphoblast globulin, low-dose prednisone, and antilymphocyte globulin for first rejection: A steroid-sparing approach to immunosuppressive therapy. Transpl Proc 15:599, 1983.

    Google Scholar 

  19. Flechner SM: Cyclosporine: A new and promising immunosuppressive agent. Urol Clin North Am 10:263, 1983.

    PubMed  CAS  Google Scholar 

  20. Johnson DE, Von Eschenbach A, Sternberg J: Bilateral renal cell carcinoma. J Urol 119:23, 1978.

    PubMed  CAS  Google Scholar 

  21. Wickham JEA: Conservative renal surgery for adenocarcinoma. Br J Urol 47:25, 1975.

    Article  PubMed  CAS  Google Scholar 

  22. Soo CS, Chuang VP, Wallace S, Charnsangavej C, Bowers TA: Segmental renal artery embolization in solitary renal carcinoma. Urology 18:420, 1981.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Martinus Nijhoff Publishers, Boston

About this chapter

Cite this chapter

Jacobs, S.C., Novick, A.C. (1984). Role of Conservative Surgery for Patients with Bilateral Kidney Tumors. In: Ratliff, T.L., Catalona, W.J. (eds) Urologic Oncology. Cancer Treatment and Research, vol 19. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2843-8_6

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2843-8_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9795-6

  • Online ISBN: 978-1-4613-2843-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics