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Nuclear Magnetic Resonance (NMR) Imaging in Urologic Oncology

  • Richard D. Williams
  • Hedvig Hricak
  • Jeffrey H. Newhouse
Part of the Cancer Treatment and Research book series (CTAR, volume 19)

Abstract

The development of nuclear magnetic resonance (NMR) imaging is among the most recent advances in diagnostic modalities designed to peer non-invasively into the functioning human in order to distinguish abnormal from normal anatomy. The enthusiasm attending the clinical emergence of NMR imaging is based on NMR’s unique ability to provide both precise anatomical detail displayed in multiple planar projections and the simultaneous delivery of physiologic and chemical information without harm to the subject. Such an approach may provide a window into the physiologic and biochemical abnormalities underlying disease processes, thus permitting predictive insights into these processes.

Keywords

Nuclear Magnetic Resonance Nuclear Magnetic Resonance Spectroscopy Spin Echo Nuclear Magnetic Resonance Signal Radio Frequency Pulse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bloch F: Nuclear induction. Phys Rev 70:460–473, 1946.CrossRefGoogle Scholar
  2. 2.
    Purcell EM, Torrey HC, Pound RV: Physics Res 69:37, 1946.CrossRefGoogle Scholar
  3. 3.
    Jackson JA, Langhan WH: Rev Scientif Instr 39:510, 1968.CrossRefGoogle Scholar
  4. 4.
    Damadian R: Tumor detection by nuclear magnetic resonance. Science 171:1151–1153, 1971.PubMedCrossRefGoogle Scholar
  5. 5.
    Lauterbur PC: Image formation by induced local interactions. Nature (London) 242:190–191, 1973.CrossRefGoogle Scholar
  6. 6.
    Lauterbur PC: Magnetic resonance zeugmatography. Pure Appl Chem 2:40, 1975.Google Scholar
  7. 7.
    Hinshaw WS, Bottomley PA, Holland GN: Radiographic thin sectioning image of the human wrist by nuclear magnetic resonance. Nature 270:722, 1977.PubMedCrossRefGoogle Scholar
  8. 8.
    Pykett IL, Newhouse JH, Buonanno FS, Brady TJ, Goldman MR, Kistler JP, Pohost GM: Principles of nuclear magnetic resonance imaging. Radiology 143:157–168, 1982.PubMedGoogle Scholar
  9. 9.
    Pykett IL: NMR imaging in medicine. Scientif Am 246:78–88, 1982.CrossRefGoogle Scholar
  10. 10.
    Oldendorf WH: NMR imaging: Its potential clinical impact. Hospital Practice, 17(9):114–128, 1982.PubMedGoogle Scholar
  11. 11.
    Brownell GL, Budinger TF, Lauterbur PC, McGeer PL: Positron tomography and nuclear magnetic resonance imaging. Science 215:619–629, 1982.PubMedCrossRefGoogle Scholar
  12. 12.
    James AE, Partain CL, Holland GN, Gore JC, Rollo FD, Harms SE, Price RR: Nuclear magnetic resonance imaging: The current state. Am J Roentgenol 138:201–210, 1981.Google Scholar
  13. 13.
    Bradley WG, Tosteson H: Basic physics of NMR. In: Nuclear Magnetic Resonance Imaging in Medicine, Kaufman L, Crooks LE, Margulis AR (eds). New York: Igaku-Shoin Medical Publishers, Inc. Chapter 2, pp 11–29, 1981.Google Scholar
  14. 14.
    NMR — An Introduction. General Electric Company Technical Manual, 1981.Google Scholar
  15. 15.
    Loeffler W, Oppelt A: Physical principles of NMR tomography. Eur J Radiol 1:338–344, 1981.PubMedGoogle Scholar
  16. 16.
    Partain CL, Price RR, Rollo FD, James AE (eds): Nuclear Magnetic Resonance (NMR) Imaging. Philadelphia: Saunders, 1983.Google Scholar
  17. 17.
    Hollis DP, Economou JS, Parks LC, Eggleston JC, Saryan LA, Czeisler JL: Nuclear magnetic resonance studies of several experimental and human malignant tumors. Cancer Res 33:2156–2160, 1973.PubMedGoogle Scholar
  18. 18.
    Eggleston JC, Saryan LA, Hollis DP: Nuclear magnetic resonance investigation of human neoplastic and abnormal non-neoplastic tissues. Cancer Res 35:1326–1332, 1975.PubMedGoogle Scholar
  19. 19.
    Wolff S, Crooks LE, Brown P, Ricci H, Painter RB: Tests for DNA and chromosomal damage induced by nuclear magnetic resonance imaging. Radiology 136:707–710, 1980.PubMedGoogle Scholar
  20. 20.
    Schwartz J, Crooks LE: NMR imaging produces no observable mutations or cytotoxicity in mammalian cells. Am J Roentgenol 139:583–585, 1982.Google Scholar
  21. 21.
    National Radiologic Protection Board: Exposure to nuclear magnetic resonance clinical imaging. Radiology XLVII: 258–260, 1981.Google Scholar
  22. 22.
    Davis PL, Crooks L, Arakawa M, McRee R, Kaufman L, Margulis AR: Potential hazards in NMR imaging: Heating effects of changing magnetic fields and RF fields on small metallic implants. Am J Roentgenol 137:857–860, 1981.Google Scholar
  23. 23.
    Crooks L, Arakawa MA, Hoenninger J, Watts J, McRee R, Kaufman L, Davis CL, Margulis AR, Degroot J: Nuclear magnetic resonance whole-body imaging operating at 3.5 KGauss. Radiology 143:169–174, 1982.PubMedGoogle Scholar
  24. 24.
    Hricak H, Crooks L, Sheldon P, Kaufman L: NMR imaging of the kidney. Radiology 146:425–432, 1983.PubMedGoogle Scholar
  25. 25.
    Hricak H, Williams RD, Moon KL, Moss AA, Alpers C, Crooks LE, Kaufman L: NMR imaging of the kidney: Part II, Renal masses. Radiology 147:765–772, 1983.PubMedGoogle Scholar
  26. 26.
    Alfidi RJ, Hoaga JR, Yousef SJ et al.: Preliminary experimental results in humans and animals with a superconducting whole-body nuclear magnetic resonance scanner. Radiology 143:175–181, 1982.PubMedGoogle Scholar
  27. 27.
    Moon KL, Hricak H, Crooks LE, Gooding CA, Moss AA, Engelstad BL, Kaufman L: Nuclear magnetic resonance imaging of the adrenal gland: A preliminary report. Radiology 147:155–160, 1983.PubMedGoogle Scholar
  28. 28.
    Young IR, Bailes DR, Burl M, Collins AG, Smith DT, McDonnell MJ, Orr JS, Banks LM, Bydder GM, Greenspan RH, Steiner RE: Initial clinical evaluation of a whole-body nuclear magnetic resonance (NMR) tomograph. J Comp Ass Tomogr 6:1–18, 1982.CrossRefGoogle Scholar
  29. 29.
    Hadley DM, Nichols DM, Smith FW: Nuclear magnetic resonance tomographic imaging in xanthogranulomatous pyelonephritis. J Urol 127:301–303, 1982.PubMedGoogle Scholar
  30. 30.
    Pollett JE, Smith FW, Mallard JR, Ah-See AK, Reid A: Whole body nuclear magnetic resonance imaging: The first report of its use in surgical practice. Br J Surg 68:498–494, 1981.CrossRefGoogle Scholar
  31. 31.
    Newhouse JH: Urinary tract imaging by nuclear magnetic resonance. Urol Radiol 4:171–175, 1982.PubMedCrossRefGoogle Scholar
  32. 32.
    Smith FW, Hutchinson JM, Mallard JR, Reid A, Johnson G, Redpath TW, Seldie D: Renal cyst or tumor? Differentiation by whole body nuclear magnetic resonance imaging. Diagnostic Imaging 50:61, 1981.PubMedGoogle Scholar
  33. 33.
    Smith FW, Reid A, Hutchinson J, Mallard JR: Nuclear magnetic resonance imaging of the pancreas. Radiology 142:677–680, 1982.PubMedGoogle Scholar
  34. 34.
    Hricak H, Higgins CB, Williams RD: NMR imaging in retroperitoneal fibrosis. Am J Roentgenol 141:35–38, 1983.Google Scholar
  35. 35.
    Doyle FH, Pennock JM, Banks LM, McDonnell MJ, Bydder GM, Steiner RE, Young JR, Clarke GJ, Pasmore T, Gilderdale DJ: Nuclear magnetic resonance imaging of the liver: Initial experience. Am J Roentgenol 138:193–200, 1982.Google Scholar
  36. 36.
    Smith FW, Mallard JR, Reid A, Hutchinson JMS: Nuclear magnetic resonance tomographic imaging in liver disease. Lancet 1:963–966, 1981.PubMedCrossRefGoogle Scholar
  37. 37.
    Hricak H, Williams RD, Spring DB, Moon KL, Hedgcock MW, Watson RA, Crooks L: Anatomy and pathology of the male pelvis as by magnetic resonance imaging. Am J Roentgenol 141:1101–1110, 1983.Google Scholar
  38. 38.
    Davis PL, Crooks LE, Margulis AR, Kaufman L: Nuclear magnetic resonance imaging: Current capabilities. West J Med 137:290–293, 1982.PubMedGoogle Scholar
  39. 39.
    Brady TJ, Goldman MR, Pykett IL, Buonanno FS, Kistler JD, Newhouse J, Hinshaw WS, Pohost GM: Proton nuclear magnetic resonance imaging of regionally ischemic canine hearts: Effect of paramagnetic proton signal enhancement. Radiology 144:343–347, 1982.PubMedGoogle Scholar
  40. 40.
    Young IR, Clarke GJ, Boiles DR, Pennock JM, Doyle FH, Bydder GM: Enhancement of relaxation rate with paramagnetic contrast agents in NMR imaging. J Com Tomogr 5:543–547, 1981.CrossRefGoogle Scholar
  41. 41.
    Brasch RC, London DA, Wesbey GE, Tozer TN, Nitrecki DE, Williams RD, Doemeny J, Tuck LD, Lallemand DP: Nuclear magnetic resonance urography enhanced by a paramagnetic nitroxide contrast agent: Preliminary report. Radiology 147:773–779, 1983.PubMedGoogle Scholar

Copyright information

© Martinus Nijhoff Publishers, Boston 1984

Authors and Affiliations

  • Richard D. Williams
  • Hedvig Hricak
  • Jeffrey H. Newhouse

There are no affiliations available

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