Tissue factor activity of cultured human vascular cells
Blood coagulation can be initiated by either the intrinsic or extrinsic coagulation pathways. Both pathways involve the sequential activation of proenzymes which circulate in plasma. The initial event in both pathways is the interaction of specific proteolytic zymogens with noncirculating constituents of the blood vessel wall.
KeywordsSmooth Muscle Cell Tissue Factor Tissue Factor Activity Normal Cell Type Extrinsic Coagulation Pathway
Unable to display preview. Download preview PDF.
- 3.Saito, H., Ratnoff, O.D., Waldman, R. and Abraham, J.P. 1975. Fitzgerald trait: Deficiency of a hitherto unrecognized agent, Fitzgerald factor, participating in surface mediated reactions of clotting, fibrinolysis, generation of kinins, and the property of diluted plasma enhancing vascular permeability. J. Clin. Invest. 55: 1082–1089.PubMedCrossRefGoogle Scholar
- 8.Gonmori, H. and Takeda, Y. 1976. Properties of human tissue thromboplastins from brain, lung, arteries, and placenta. Thrombos. Haemostas. (Stuttg) 36: 90–103.Google Scholar
- 16.Green, D., Ryan, C., Malandruccolo, N. and Nadler, H.L. 1971. Characterization of the coagulant activity of cultured human fibroblasts. Blood J. Hematol. 37: 47–51.Google Scholar