Scanning Electron Microscopic Cytochemistry of Leukemic Cells

  • D. Soligo
  • E. Pozzoli
  • G. Lambertenghi-Deliliers
Part of the Developments in Oncology Series book series (DION, volume 14)


Scanning electron microscopy (SEM) was widely applied to the study of leukemic cells in the early 1970s [1, 2, 5] (the results of these studies are discussed in chapter 26). It soon became apparent that cell surface morphology can vary widely according to preparation procedures [4], and probably according to a variety of as yet unknown factors such as metabolic or environmental conditions. In fact, although cell surface features are typical enough to permit cell type identification in a very limited number of hematological malignancies [1], in the majority of cases SEM has proved to be of little routine use in the diagnosis of leukemia.


Backscatter Electron Imaging Iron Carbonyl Granulocytic Leukemia Iron Carbonyl Particle Acute Monoblastic Leukemia 
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© Martinus Nijhoff Publishing, Boston/The Hague/Dordrecht/Lancaster 1984

Authors and Affiliations

  • D. Soligo
  • E. Pozzoli
  • G. Lambertenghi-Deliliers

There are no affiliations available

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