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Plasma Cell Leukemia

Ultrastructural Aspects in Diagnosis

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Part of the book series: Developments in Oncology Series ((DION,volume 14))

Abstract

Plasma cell leukemia (PCL) is an infrequent condition that accounts for less than 2% of the plasmacytic dyscrasias [1]. It may appear as a terminal phase of the classical form of multiple myeloma, or as an acute leukemic condition, clinically identical with other forms of acute leukemia [2]. The diagnosis is based on the presence of plasma cells in the peripheral blood, which may exceed 50% of the total white blood cell count, and may be presented at different stages of maturation, from immature plasmablasts to mature plasmacytes. The light microscopy examination of the plasma cells is usually sufficient to establish the diagnosis but, in some cases, the distinction between leukemic myelomatosis and chronic lymphocytic leukemia is rather difficult [3, 4], and the use of electron microscopy is necessary to achieve the right decision.

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© 1984 Martinus Nijhoff Publishing, Boston/The Hague/Dordrecht/Lancaster

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Djaldetti, M. (1984). Plasma Cell Leukemia. In: Polliack, A. (eds) Human Leukemias. Developments in Oncology Series, vol 14. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2823-0_17

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  • DOI: https://doi.org/10.1007/978-1-4613-2823-0_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9785-7

  • Online ISBN: 978-1-4613-2823-0

  • eBook Packages: Springer Book Archive

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