Abstract
Gossypol does indeed prove to be a simple, safe, economical, and reversible method of male contraception, an understanding of its biochemical mechanism of action will be essential, since such elucidation may lead to the development of synthetic compounds exhibiting the desired antifertility effect without the toxicity so far noted in animals and in humans.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
C. Y. Lee and H. V. Mailing, Selective inhibition of lactate dehydrogenase-X by a male antifertility agent-gossypol, Fed. Proc., 40:2790 (1981).
C. Y. Lee, Y. S. Moon, J. H. Yuan, and A. F. Chen, Enzyme inactibation and inhibition by gossypol, Mol. Cell. Biochem., Vol. 47, pp. 65–70 (1982).
E. Goldberg, Isozymes in testes and spermatozoa, in: “Isozymes: Current Topics in Biological and Medical Research” (M. C. Rattazzi, J. G. Scandalios, and G. Whitt, eds.), Vol. 1, p. 79, Alan R. Liss, Inc., New York (1977).
C.Y. Lee and H. V. Mailing, 1981, op. cit. (see Ref. 1).
Ibid.
C. Y. Lee, et al.,11982, op. cit. (see Ref. 2).
E. Goldberg, 1977, op. cit. (see Ref. 3).
C. Y. Lee, et al., 1982, op. cit. (see Ref. 2).
H. Pösö, K. Wichmann, J. Jänne, and T. Luukkainen, Gossypol, a powerful inhibitor of human spermatozoal metabolism, Lancet 1: 885 (1980).
M. B. Abou-Donia, Physiological effect and metabolism of gossypol, Residual Reviews, Vol. 61, p. 126, Springer-Verlag, New York (1976).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Plenum Press, New York
About this chapter
Cite this chapter
Lee, CY.G., Moon, Y.S., Duleba, A., Chen, A.F., Yuan, J.H., Gomel, V. (1985). Biochemical Studies of Gossypol. In: Segal, S.J. (eds) Gossypol. Reproductive Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2809-4_18
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2809-4_18
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9729-1
Online ISBN: 978-1-4613-2809-4
eBook Packages: Springer Book Archive