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The Clinical Implications of Dietary Fiber

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Part of the book series: Advances in Nutritional Research ((ASIB,volume 110))

Abstract

In the decade since Trowell and Burkitt (1975) hypothesized that many diseases seen in the West were due to overconsumption of refined carbohydrate foods, there has been a rekindling of interest in many hitherto neglected aspects of human nutrition. This in turn has been reflected in the pronouncements of official bodies concerned with health and public policy (American Diabetes Association, 1979; Canadian Diabetes Association, 1981; British Diabetic Association, 1981; U.S. Senate Select Committee on Nutrition and Human Needs, 1977; American Heart Association, 1982) and by the generous coverage given in the popular press to some of the issues involved (Alen, 1982; Engel, 1982; Fellman, 1982; Gillie, 1977). However, interest in the possible value of plant foods is not solely the result of the ’fiber hypothesis.’ The drive to substitute unsaturated for saturated fat during previous decades was a force acting in the same direction. Both moves implicitly favored a reduction in the intake of animal products and an increased consumption of plant foods.

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References

  • Alen, C., 1982, The food that fights diabetes, heart disease and high blood pressure, National EnquirerJanuary5, p. 2

    Google Scholar 

  • American Diabetes Association, Committee on Food and Nutrition, 1979, Special report: principles of nutrition and dietary recommendations for individuals with diabetes mellitus, Diabetes Care 2: 520

    Google Scholar 

  • American Heart Association, 1982, Report of Nutrition Committee: Rationale of the dietheart statement of the American Heart Association, Circulation 65: 839A

    Google Scholar 

  • Anderson, G.H., 1979, Control of protein and energy intake: role of plasma amino acids and brain neurotransmitters, CanJ. Physiol. Pharmacol 57: 1043

    CAS  Google Scholar 

  • Anderson, I.H., Levine, A.S., and Levitt, M.D., 1981, Incomplete absorption of the carbohydrate in all-purpose wheat flour, N. EnglJ. Med 304: 891

    CAS  Google Scholar 

  • Anderson, J.W., and Chen, W.L., 1979, Plant fiber: carbohydrate and lipid metabolism, Am. J. Clin. Nutr 32: 346

    CAS  Google Scholar 

  • Anderson, J.W., and Ward, K., 1979, High-carbohydrate, high-fiber diets for insulin-treated men with diabetes mellitus, Am J Clin Nutr 32: 2312

    CAS  Google Scholar 

  • Anderson, J.W., Ferguson, S.K., Karounos, D., O’Malley, L., Seiling, B., and Chen, W.J.L., 1980, Mineral and vitamin status on high-fiber diets: long-term studies of diabetic patients, Diabetes Care 3: 38

    CAS  Google Scholar 

  • Bingwen, L., Zhaofeny, W., Wanshen, L., and Rongjue, Z., 1981, Effects of bean meal on serum cholesterol and triglycerides, Chin. Med. J 94: 455

    Google Scholar 

  • British Diabetic Association, Nutrition Subcommittee of the Medical Advisory Committee, Dietary Recommendations for Diabetes for the 1980’s, final draft (July 1981)

    Google Scholar 

  • Brodribb, A.J.M., and Groves, C., 1978, Effect of bran particle size on stool weight, Gut 19: 60

    CAS  Google Scholar 

  • Brodribb, A.J.M., and Humphreys, D.M., 1976, Diverticular disease: three studies, Br. Med. J 1: 424

    CAS  Google Scholar 

  • Brunzell, J.D., Lerner, R.L., and Hazzard, W.R., 1971, Improved glucose tolerance with high carbohydrate feeding in mild diabetes, N. Engl. J. Med 284: 521

    CAS  Google Scholar 

  • Burkitt, D.P., 1971, Epidemiology of cancer of the colon and rectum, Cancer 28: 3

    CAS  Google Scholar 

  • Burkitt, D.P., and Meisner, P., 1979, How to manage constipation with a high fiber diet, Medical Report 24: 30

    Google Scholar 

  • Campbell, G.D., 1971, Frequency of diabetes with special respect to diet, in: Diabetes, Proc. 7th Congress Int. Diab. Fedn., (R.R. Rodrigues and J. Vallance-Owen, eds.) Excerpta Medica, Amsterdam, (Int. Cong. Ser., 231 ) 1971

    Google Scholar 

  • Canadian Diabetes Association, Special Report of Committee on Guidelines for the Nutri¬tional Management of Diabetes Mellitus, 1981, J. Can. Diet. Assoc 42: 110

    Google Scholar 

  • Capron, J.P., Pajenneville, H., Dumont, M., Dupas, J.L., and Loniaug, A., 1978, Evidence for an association between cholelithiasis and hiatus hernia, Lancet 2: 329

    CAS  Google Scholar 

  • Carroll, K.K., 1978, The role of dietary protein in hypercholesterolemia and atherosclerosis, Lipids 13: 360

    CAS  Google Scholar 

  • Carroll, K.K., and Hamilton, R.M.G., 1975, Effects of dietary protein and carbohydrate on plasma cholesterol levels in relation to atherosclerosis, J. Food Sci 40: 18

    CAS  Google Scholar 

  • Carroll, K.K., Giovannetti, P.M., Huff, M.W., Moase, O., Roberts, D.C.K., and Wolfe, B.M., 1978., Hypocholesterolemic effect of substituting soybean protein for animal protein in the diet of healthy young women, Am. J. Clin. Nutr, 31: 1312

    Google Scholar 

  • Caspary, W.F., 1978, Sucrose malabsorption in man after ingestion of alpha-glucosidehydrolase inhibitor, Lancet 1: 1231

    CAS  Google Scholar 

  • Christiansen, J.W., Bonnevie-Nielsen, V., Svendsen, P.A., Rubin, P., Ronn, B., and Nerup, J., 1980, Effect of guar gum on 24-hour insulin requirements of insulin-dependent diabetic subjects as assessed by an artificial pancreas, Diabetes Care 3: 659

    CAS  Google Scholar 

  • Cohen, M., Leong, V.W., Salmon, E., and Martin, F.I.R., 1980, Role of guar and dietary fibre in the management of diabetes mellitus, Med. J. Aust 1: 59

    CAS  Google Scholar 

  • Connor, W.E., and Connor, S.L., 1982, The dietary treatment of hyperlipidemia: rationale, technique and efficacy, Med. Clin. N. Am 66: 485

    CAS  Google Scholar 

  • Crapo, P.A., Reaven, G., and Olefsky, J., 1977, Postprandial plasma-glucose and -insulin responses to different complex carbohydrates, Diabetes 26: 1178

    CAS  Google Scholar 

  • Cummings, J.H., 1981, Progress report: Short chain fatty acids in the human colon, Gut 22: 763

    CAS  Google Scholar 

  • Cummings, J.H., Hill, M.J., Jenkins, D.J.A., Pearson, J.R., and Wiggins, H.S., 1976, Changes in fecal composition and colonic function due to cereal fiber, Am. J. Clin. Nutr 29: 1468

    CAS  Google Scholar 

  • Cummings, J.H., Branch, W., Jenkins, D.J.A., Southgate, D.A.T., Houston, H., and James, W.P.T., 1978, Colonic response to dietary fibre from carrot, cabbage, apple, bran, and guar gum, Lancet 1: 5

    CAS  Google Scholar 

  • Cummings, J.H., Southgate, D.A.T., Branch, W.J., Wiggins, H.S., Houston, H., Jenkins, D.J.A., Jivraj, T., and Hill, M.J., 1979, The digestion of pectin in the human gut and its effect on calcium absorption and large bowel function, Br. J. Nutr 41: 477

    CAS  Google Scholar 

  • Doi, K., Matsuuram, M., Kawara, A., and Baba, S., 1979, Treatment of diabetes with glucomannan (Konjac mannan), Lancet 1: 987

    CAS  Google Scholar 

  • Durrington, P.N., Manning, A.P., Bolton, C.H., and Hartog, M., 1976, Effect of pectin on serum lipids and lipoproteins, whole-gut transit-time and stool weight, Lancet 2: 394

    CAS  Google Scholar 

  • Eastwood, M.A., and Hamilton, D., 1968, Studies on the adsorption of bile salts to nonab¬sorbed components of the diet, Biochim. Biophys. Acta 152: 165

    CAS  Google Scholar 

  • Eastwood, M.A., Kirkpatrick, J.R., Michell, W.D., Bone, A., and Hamilton, T., 1973, Effects of dietary supplements of wheat bran and cellulose on faeces and bowel function, Br. Med. J 4: 392

    CAS  Google Scholar 

  • Elsenhans, B., Sufke, U., Blume, R., and Caspary, W.F., 1980, The influence of carbo¬hydrate gelling agents on rat intestinal transport of monosaccharides and neutral amino acids in vitro, Clin. Sci 59: 373

    CAS  Google Scholar 

  • Engel, J., 1982, Is there enough fibre in your diet?Chatelaine 55(6): 24

    Google Scholar 

  • Fahrenbach, M.J., Riccardi, B.A., Saunders, J.L., Lowrie, I.N., and Heider, J.G., 1965, Comparative effects of guar gum and pectin on human cholesterol levels, Circulation 31/32: Suppl. 2: 11

    Google Scholar 

  • Fellman, B., 1982, Put pectin to work for you, Prevention 4: 109

    Google Scholar 

  • Gatti, E., and Sirtori, C.R., 1977, Soybean-protein diet and plasma-cholesterol, Lancet 1: 805

    Google Scholar 

  • Gerard, J., Luyckx, A.S., and Lefebvre, P.J., 1982, Improvement of metabolic control in insulin dependent diabetics treated with the alpha-glucosidase inhibitor Acarbose for two months, Diabetologia 21: 446

    Google Scholar 

  • Gillie, O., 1977, Indian bean gum helps diabetics and slimmers, The Sunday Times, Oct. 23

    Google Scholar 

  • Gold, L.A., McCourt, J.P., and Merimee, T.J., 1980, Pectin: an examination in normal subjects, Diabetes Care 3: 50

    CAS  Google Scholar 

  • Gould, R.G., 1955, Absorbability of beta-sitosterol, Trans. N. Y. Acad. Sci 18: 129

    CAS  Google Scholar 

  • Grande, F., Anderson, J.T., and Keys, A., 1965, Effect of carbohydrates of leguminous seeds, wheat and potatoes on serum cholesterol concentration in man., J Nutr 86: 313

    CAS  Google Scholar 

  • Haber, G.B., Heaton, K.W., Murphy, D., and Burroughs, L.F., 1977, Depletion and disruption of dietary fibre: effects on satiety, plasma-glucose, and serum-insulin, Lancet 2: 679

    CAS  Google Scholar 

  • Heaton, K.W., 1981, Is bran useful in diverticular disease?Br. Med. J 2: 1523

    Google Scholar 

  • Heaton, K.W., and Pomare, E.W., 1974, Effect of bran on blood lipids and calcium, Lancet 1: 49

    CAS  Google Scholar 

  • Heaton, K.W., Thornton, J.R., and Emmett, P.M., 1979, Treatment of Crohn’s disease with an unrefined-carbohydrate, fibre-rich diet, Br. Med. J 2: 764

    CAS  Google Scholar 

  • Hernandez, A., and Jaffe, W.G., 1968, Inhibitor of pancreatic amylase from beans(Phaseolus vulgaris)., Acta. Cient. Venez 19: 183

    CAS  Google Scholar 

  • Hernandez, A., and Jaffe, W.G., 1968, Inhibitor of pancreatic amylase from beans(Phaseolus vulgaris)., Acta. Cient. Venez 19: 183

    CAS  Google Scholar 

  • Hillebrand, I., Boehme, K., Frank, G., Fink, H., and Berchtold, P., 1979, The effects of the alpha-glucosidase inhibitor Bay g 5421 (Acarbose) on meal-stimulated elevations of circulating glucose, insulin, and triglyceride levels in man, Res. Exp. Med. (Berl.) 175: 81

    CAS  Google Scholar 

  • Hjermann, I., Byre, K.V., Holme, I., and Lerer, P., 1981, Effect of diet and smoking intervention on the incidence of coronary heart disease: Report from the Oslo Study Group of a randomised trial of healthy men, Lancet 2: 1303

    CAS  Google Scholar 

  • Holt, S., Heading, R.C., Carter, D.C., Prescott, L.F., and Tothill, P., 1979, Effect of gel fibre on gastric emptying and absorption of glucose and paracetamol, Lancet 1: 636

    CAS  Google Scholar 

  • Jaffe, W.G., and Vega Lette, C.L., 1968, Heat-labile growth inhibiting factors in beans (Phaseolus vulgaris), J Nutr 94: 203

    CAS  Google Scholar 

  • Jaffe, W.G., Moreno, R., and Wallis, V., 1973, Amylase inhibitors in legume seeds, Nutr. Rep. Int 7: 169

    CAS  Google Scholar 

  • Jeffrys, D.B., 1974, The effect of dietary fibre on the response to orally administered glucose, Proc. Nutr. Soc 33: 11A

    Google Scholar 

  • Jenkins, D.J.A., Hill, M.S., and Cummings, J.H., 1975a, Effect of wheat fiber on blood lipids, fecal steroid excretion and serum iron, Am. J. Clin Nutr 28: 1408

    CAS  Google Scholar 

  • Jenkins, D.J.A., Leeds, A.R., Newton, C., and Cummings, J.H., 1975b, Effect of pectin, guar gum, and wheat fibre on serum-cholesterol, Lancet 1: 1116

    CAS  Google Scholar 

  • Jenkins, D.J.A., Leeds, A.R., Gassull, M.A., Wolever, T.M.S., Goff, D.V., Alberti, K.G.M.M., and Hockaday, T.D.R., 1976a, Unabsorbable carbohydrates and diabetes: decreased post-prandial hyperglycaemia, Lancet 2: 172

    CAS  Google Scholar 

  • Jenkins, D.J.A., Leeds, A.R., Gassull, M.A., Houston, H., Goff, D.V., and Hill, M.J., 1976b, The cholesterol lowering properties of guar and pectin, Clin. Sci. Mol. Med 51: 8

    Google Scholar 

  • Jenkins, D.J.A., Gassull, M.A., Leeds, A.R., Metz, G., Dilawari, J.B., Slavin, B., and Blendis, L.M., 1977a, Effect of dietary fiber on complications of gastric surgery: prevention of postprandial hypoglycemia by pectin, Gastroenterology 73: 215

    CAS  Google Scholar 

  • Jenkins, D.J.A., Leeds, A.R., Gassull, M.A., Cochet, B., and Alberti, K.G.M.M., 1977b, Decrease in postprandial insulin and glucose concentrations by guar and pectin, Ann. Intern. Med 86: 20

    CAS  Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Hockaday, T.D.R., Leeds, A.R., Howarth, R., Bacon, S., Apling, E.C., and Dilawari, J., 1977c, Treatment of diabetes with guar gum, Lancet 2: 779

    CAS  Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Leeds, A.R., Gassull, M.A., Haisman, P., Dilawari, J., Goff, D.V., Metz, G.L., and Alberti, K.G.M.M., 1978, Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity, Br. Med. J 1: 1392

    CAS  Google Scholar 

  • Jenkins, D.J.A., Leeds, A.R., Slavin, B., Mann, J., and Jepson, E.M., 1979a, Dietary fiber and blood lipids: reduction of serum cholesterol in type 11 hyperlipidemia by guar gum, Am. J. Clin. Nutr 32: 16

    CAS  Google Scholar 

  • Jenkins, D.J.A., Nineham, R., Craddock, C., Craig-McFeely, P., Donaldson, K., Leigh, T., and Snook, J., 1979b, Fibre and diabetes, Lancet 1: 434

    Google Scholar 

  • Jenkins, D.J.A., Taylor, R.H., Nineham, R., Goff, D.V., Bloom, S.R., Sarson, D., and Alberti, K.G.M.M., 1979c, Combined use of guar and acarbose in reduction of post¬prandial glycaemia, Lancet 2: 924

    CAS  Google Scholar 

  • Jenkins, D.J.A., Reynolds, D., Leeds, A.R., Waller, A.L., and Cummings, J.H., 1979d, Hypocholesterolemic action of dietary fiber unrelated to fecal bulking effect, Am. J. Clin. Nutr 32: 2430

    CAS  Google Scholar 

  • Jenkins, D.J.A., Bloom, S.R., Albuquerque, R.H., Leeds, A.R., Sarson, D.L., Metz, G.L., and Alberti, K.G.M.M., 1980a, Pectin and complications after gastric surgery: normalisation of postprandial glucose and endocrine responses, Gut 21: 574

    CAS  Google Scholar 

  • Jenkins, D.J.A., Reynolds, D., Slavin, B., Leeds, A.R., Jenkins, A.L., and Jepson, E.M., 1980b, Dietary fiber and blood lipids: treatment of hypercholesterolemia with guar crispbread, Am. J. Clin. Nutr 33: 575

    CAS  Google Scholar 

  • Jenkins, D.J.A. Wolever, T.M.S., Bacon, S., Nineham, R., Lees, R., Rowden, R., Love, M., and Hockaday, T.D.R., 1980c, Diabetic diets: high carbohydrate combined with high fiber, Am. J. Clin. Nutr 33: 1729

    CAS  Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Taylor, R.H., Barker, H., and Fielden, H., 1980d, Exceptionally low blood glucose response to dried beans: comparison with other carbohydrate foods, Br. Med. J 2: 578

    Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Taylor, R.H., Barker, H., Fielden, H., Baldwin, J.M., Bowling, A.C., Newman, H.C., Jenkins, A.L., and Goff, D.V., 1980e, Glycemic index of foods: a physiological basis for carbohydrate exchange, Am. J. Clin. Nutr34: 362

    Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Taylor, R.H., Barker, H., Fielden, H., and Jenkins, A.L., 1980f, Effect of guar crispbread with cereal products and leguminous seeds on blood glucose concentrations of diabetes, Br. Med. J 2: 1248

    Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Taylor, R.H., Ghafari, H., Jenkins, A.L., Barker, H., and Jenkins, M.J.A., 1980g, Rate of digestion of foods and postprandial glycaemia in normal and diabetic subjects, Br. Med. J 2: 14

    Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Taylor, R.H., Reynolds, D., Nineham, R., and Hockaday, T.D.R., 1980h, Diabetic glucose control, lipids, and trace elements on long-term guar, Br. Med. J 1: 1353

    Google Scholar 

  • Jenkins, D.J.A., Taylor, R.H., Goff, D.V., Fielden, H., Misiewicz, J.J., Sarson, D.L., Bloom, S.R., and Alberti, K.G.M.M., 1981a, Scope and specificity of Acarbose in slowing carbohydrate absorption in man, Diabetes 30: 951

    CAS  Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Taylor, R.H., Barker, H.M., Fielden, H., and Gassull, M.A., 1981b, Lack of effect of refining on the glycemic response to cereals, Diabetes Care 4: 509

    CAS  Google Scholar 

  • Jenkins, D.J.A., Barker, H.M., Taylor; R.H., and Fielden, H., 1982a, Low dose Acarbose without symptoms of malabsorption in the dumping syndrome, Lancet 1: 109

    CAS  Google Scholar 

  • Jenkins, D.J.A., Ghafari, H., Wolever, T.M.S., Taylor, R.H., Jenkins, A.L., Barker, H.M., Fielden, H., and Bowling, A.C., 1982b, Relationship between rate of digestion of foods and post-prandial glycaemia, Diabetologia 22: 450

    CAS  Google Scholar 

  • Jenkins, D.J.A., Thorne, M.J., Camelon, K., Jenkins, A.L., Rao, AN., Taylor, R.H., Thompson, L.U., Kalmusky, J., Reichert, R., and Francis, T., 1982c, Effect of processing on digestibility and the blood glucose response: a study of lentils, Am. J. Clin. Nutr 36: 1093

    CAS  Google Scholar 

  • Jenkins, D.J.A., Wolever, T.M.S., Taylor, R.H., Griffiths, C., Krzeminska, K., Lawrie, J.A., Bennett, C.M., Goff, D.V., Sarson, D.L., and Bloom, S.R., 1982d, Slow release dietary carbohydrate improves second meal tolerance, Am. J. Clin. Nutr 35: 1339

    CAS  Google Scholar 

  • Kasper, H., and Sommer, H., 1979, Dietary fiber and nutrient intake in Crohn’s disease., Am. J Clin. Nutr 32: 1898

    CAS  Google Scholar 

  • Kasper, H., Zilly, W., Fassl, H., and Fehle, F., 1979, The effect of dietary fiber on post¬prandial serum digoxin concentration in man, Am. J. Clin. Nutr 32: 2436

    CAS  Google Scholar 

  • Kay, R.M., and Truswell, A.S., 1977, Effects of citrus pectin on blood lipids and fecal steroid excretion in man, Am. J. Clin. Nutr 30: 171

    CAS  Google Scholar 

  • Kay, R.M., Wayman, M., and Strasberg, S.M., 1979, Effect of autohydrolysed lignin and lactulose on gallbladder bile (GB) composition in the hampster, Gastroenterology 76: 1167 (abstract)

    Google Scholar 

  • Keys, A., Grande, R., and Anderson, J.T., 1961, Fiber and pectin in the diet and serum cholesterol concentration in man, Proc. Soc. Exp. Biol. Med 106: 555

    CAS  Google Scholar 

  • Khan, P., Macrae, R., and Robinson, R.K., 1979, The novel use of a chromatography refractive index detector for monitoring model dialysis experiments, Lab. Pract 28: 260

    CAS  Google Scholar 

  • Kiehm, T.G., Anderson, J.W., and Ward, K., 1976, Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men, Am. J. Clin. Nutr 29: 895

    CAS  Google Scholar 

  • Kirby, R.W., Anderson, J.W., Sieling, B., Rees, E.D., Chen, W.L., Miller, R.E., and Kay, R.M., 1981, Oat-bran intake selectively lowers serum low-density lipoprotein concentrations, Am. J. Clin. Nutr 34: 824

    CAS  Google Scholar 

  • Kirwan, W.O., Smith, AX, McConnell, A.A., Mitchell, W.D., and Eastwood, M.A., 1974, Action of different bran preparations on colonic function, Br. Med. J 4: 187

    CAS  Google Scholar 

  • Kneen, E., and Sandstedt, R. M., 1946, Distribution and general properties of an amylase inhibitor in cereals., Arch. Biochem 9: 235

    CAS  Google Scholar 

  • Kritchevsky, D., 1978, Fiber, lipids, and atherosclerosis., Am. J. Clin. Nutr 31: S65

    CAS  Google Scholar 

  • Kritchevsky, D., and Story, J.A., 1974, Binding of bile salts in vitro by nonnutritive fiber, J. Nutr 104: 458

    CAS  Google Scholar 

  • Kritchevsky, D., and Story, J.A., 1975, In vitro binding of bile acids and bile salts, Am. J. Cl in. Nutr 28: 305

    CAS  Google Scholar 

  • Kritchevsky, D., Tepper, S.A., and Story, J.A., 1978, Influence of soy protein and casein on atherosclerosis in rabbits, Fed. Proc 37: 747

    Google Scholar 

  • Kromhout, D., Bosschieter, E.B., and de Lezenne Coulander, C., 1982, Dietary fibre and 10-year mortality from coronary heart disease, cancer, and all causes, Lancet 2: 518

    CAS  Google Scholar 

  • Leeds, A.R., Ralphs, D.N., Boulos, P., Ebied, R., Metz, G.L., Dilawari, J.B., Elliot, A., and Jenkins, D.J.A., 1978, Pectin and gastric emptying in the dumping syndrome., Proc. Nutr. Soc 37: 23A

    Google Scholar 

  • Leeds, A.R., Ralphs, D.N.L., Ebied, F., Metz, G., and Dilawari, J.B., 1981, Pectin in the dumping syndrome: Reduction of symptoms and plasma volume changes, Lancet 1: 1075

    CAS  Google Scholar 

  • Levitt, N.S., Vinik, A.I., Sive, A.A., Child, P.T., and Jackson, W.P., 1980, The effect of dietary fiber on glucose and hormone responses to a mixed meal in normal subjects and in diabetic subjects with and without autonomic neuropathy, Diabetes Care 3: 515

    CAS  Google Scholar 

  • Lewis, B., Hammett, F., Katen, M., Kay, R.M., Merkx, I., Nobels, A., Miller, N.E., and Swan, AN., 1981, Towards an improved lipid-lowering diet: Additive effects of changes in nutrient intake, Lancet 2: 1310

    CAS  Google Scholar 

  • Liener, I.E., 1979, The nutritional significance of plant protease inhibitors, Proc. Nutr. Soc 38: 109

    CAS  Google Scholar 

  • Lindner, P., and Moller, B., 1973, Lignin: a cholesterol lowering agent?Lancet 2: 1259. Littlewood, E.R., Ornstein, M.H., McLean Baird, I., and Cox, A.G., 1981, Doubts about diverticular disease, Br. Med. J 2: 1524

    Google Scholar 

  • Malinow, M.R., McLaughlin, P., Stafford, C., Livingstone, A.L., Kohler, G.O., and Cheeke, P.R., 1979, Comparative effects of alfalfa saponins and alfalfa fiber on cholesterol absorption in rats, Am. J. Clin. Nutr 32: 1810

    CAS  Google Scholar 

  • Mathur, K.S., Khan, M.A., and Sharma, R.D., 1968, Hypocholesterolaemic effect of bengal gram: a long-term study in man, Br. Med. J 1: 30

    CAS  Google Scholar 

  • Mattoo, A.K., and Modi, V.V., 1970, Partial purification and properties of enzyme inhibitors from unripe mangos, Enzymologia 39: 237

    CAS  Google Scholar 

  • McCance, R.A., Prior, K.M., and Widdowson, E.M., 1953, A radiological study of the rate of passage of brown and white bread through the digestive tract of man., Br J Nutr 7: 98

    CAS  Google Scholar 

  • McLoughlin, J.C., Buchanan, K.D., and Alam, M.J., 1979, A glucoside-hydrolase inhibitor in treatment of dumping syndrome, Lancet 2: 603

    CAS  Google Scholar 

  • Miettinen, T.A., and Tarpila, S., 1977, Effect of pectin on serum cholesterol, fecal bile acids, and biliary lipids in normolipidemic and hyperlipidemic individuals, Clin. Chim. Acta 79: 471

    CAS  Google Scholar 

  • Militzer, W., Ikeda, C., and Kneen, E., 1946, The preparation and properties of an amylase inhibitor of wheat, Arch. Biochem 9: 30

    Google Scholar 

  • Miller, B.S. and Kneen, E., 1947, The amylase inhibitor of Leoti sorghum, Arch. Biochem. Biophys 15: 251

    CAS  Google Scholar 

  • Miranda, P.M., and Horwitz, D.L., 1978, High fiber diets in the treatment of diabetes mellitus, Ann. Intern. Med 88: 482

    CAS  Google Scholar 

  • Morgan, L.M., Goulder, T.J., Tsiolakis, D., Marks, V., and Alberti, K.G.M.M., 1979, The effect of unabsorbable carbohydrate on gut hormones: modification of postprandial GIP secretion by guar, Diabetologia 17: 85

    CAS  Google Scholar 

  • Morris, J.N., Marr, J.W., and Clayton, D.G., 1977, Diet and heart: a postscript, Br. Med. J 2: 1307

    CAS  Google Scholar 

  • Munoz, J.M., Sandstead, H.H., Jacob, R.A., Logan, G.M. Jr., Reck, S.J., Klevay, L.M., Dintzis, F.R., Inglett, G.E., and Shuey, W.C., 1979, Effects of some cereal brans and textured vegetable protein on plasma lipids, Am. J. Clin Nutr 32: 580

    CAS  Google Scholar 

  • Nachbar, M.S., and Oppenheim, J.D., 1980, Lectins in the United States diet: a survey of lectins in commonly consumed foods and a review of the literature, Am. J. Clin. Nutr 33: 2338

    CAS  Google Scholar 

  • Narayana Rao, M., Shurpalekar, K.S., and Sundaravalli, O.E., 1967, An amylase inhibitor in Colocasia esculenta, Indian J. Biochem 4: 185

    Google Scholar 

  • O’Connor, N., Tredger, J., and Morgan, L., 1981, Viscosity differences between various guar gums, Diabetologia 20: 612

    Google Scholar 

  • O’Dea, K., Nestel, P.J., and Antonoff, L., 1980, Physical factors influencing postprandial glucose and insulin responses to starch., Am. J. Clin. Nutr 33: 760

    Google Scholar 

  • O’Dea, K., Snow, P., and Nestel, P., 1981, Rate of starch hydrolysis in vitro as a predictor of metabolic responses to complex carbohydrate in vivo., Am. J Clin. Nutr 34: 1991

    Google Scholar 

  • Ornstein, M.H., Littlewood, E.R., McLean Baird, I., Fowler, J., North, W.R.S., and Cox, A.G., 1981, Are fibre supplements really necessary in diverticular disease of the colon? A controlled clinical trial, Br. Med. J 1: 1353

    Google Scholar 

  • Painter, N.S., and Burkitt, D.P., 1971, Diverticular disease of the colon: a deficiency disease of Western civilisation, Br. Med. J 2: 450

    CAS  Google Scholar 

  • Painter, N.S., and Burkitt, D.P., 1975, Diverticular disease of the colon, a 20th Century problem., Clin. Gastroenterol 4: 3

    CAS  Google Scholar 

  • Painter, N.S., Almeida, A.Z., and Colebourne, K.W., 1972, Unprocessed bran in treatment of diverticular disease of the colon, Br. Med. J 1: 137

    Google Scholar 

  • Pak, C.W., Delea, C.S., and Bartter, F.C., 1974, Treatment of recurrent nephrolithiasis with cellulose phosphate, N. Engl. J. Med 290: 175

    CAS  Google Scholar 

  • Palmer, G.H., and Dixon, D.G., 1966, Effect of pectin dose on serum cholesterol levels, Am. J. Clin. Nutr 18: 437

    CAS  Google Scholar 

  • Pomare, E.W., Heaton, K.W., Low-Beer, T.S., and Espiner, H.J., 1976, The effect of wheat bran upon bile salt metabolism and upon the lipid composition of bile in gallstone patients, Am. J. Dig. Dis 21: 521

    CAS  Google Scholar 

  • Potter, J.D., Illman, R.J., Calvert, G.D., Oakenfull, D.G., and Topping, O.C., 1980, Soya saponins, plasma lipids, lipoproteins and fecal bile acids: a double blind cross-over study, Nutr. Rep. Int 22: 521

    Google Scholar 

  • Puls, W., and Keup, U., 1973, Influence of an (x-amylase inhibitor (Bay d 7791) on blood glucose, serum insulin and NEFA in starch loading tests in rats, dogs and man, Diabetologia 9: 97

    CAS  Google Scholar 

  • Puzstai, A., Clarke, E.M.W., and King, T.P., 1979, The nutritional toxicity of Phaseolus vulgaris lectins, Proc. Nutr. Soc 38: 115

    Google Scholar 

  • Reinhold, J.G., Faradji, B., Abadi, P., and Ismail-Beigi, F., 1976, Decreased absorption of calcium, magnesium, zinc and phosphorus by humans due to increased fiber and phosphorus consumption as wheat bread, J. Nutr 106: 493

    CAS  Google Scholar 

  • Rivellese, A., Riccardi, G., Giacco, A., Pacioni, D., Genovese, S., Mattioli, P.L., and Mancini, M., 1980, Effect of dietary fibre on glucose control and serum lipoproteins in diabetic patients, Lancet 2: 447

    CAS  Google Scholar 

  • Salen, G. Ahrens, E.H. Jr., and Grundy, S.M., 1970, Metabolism of /3-sitosterol in man., J Clin Invest 49: 952

    CAS  Google Scholar 

  • Salunkhe, D.K., and Wu, M.T., 1977, Toxicants in plants and plant products, CRC Critical Reviews in Food Science and Nutrition 9: 265

    CAS  Google Scholar 

  • Saraswathy Devi, K., and Kurup, P.A., 1973, Hypolipidaemic activity of the protein and polysaccharide fraction from Phaseol us Mungo (blackgram) in rats fed a high-fat high-cholesterol diet, Atherosclerosis 18: 389

    Google Scholar 

  • Saraswathy Devi, K., and Kurup, P.A., 1979, Effects of certain Indian pulses on the serum, liver and aortic lipid levels in rats fed a hypercholesterolaemic diet, Atherosclerosis 11: 479

    Google Scholar 

  • Schauberger, G., Brinck, U.C., Suldner, G., Spaethe, R., Niklas, L., and Otto, H., 1978, Exchange of carbohydrates according to their effect on blood glucose, Diabetes 26: 415 (abstract)

    Google Scholar 

  • Simpson, R.W., Mann, J.1., Eaton, J., Carter, R., and Hockaday, T.D.R., 1979a, High carbohydrate diets in insulin-dependent diabetes, Br. Med. J 2: 523

    CAS  Google Scholar 

  • Simpson, R.W., Mann, J.I., Eaton, J., Moore, R.A., Carter, R., and Hockaday, T.D.R., 1979b, Improved glucose control in maturity-onset diabetes treated with high-carbohydrate-modified fat diet, Br. Med. J 1: 1753

    CAS  Google Scholar 

  • Simpson, H.C.R., Simpson, R.W., Lousley, S., Carter, R.D., Geekie, M., Hockaday, T.D.R., and Mann, J.I., 1981, A high carbohydrate leguminous fibre diet improves all aspects of diabetic control, Lancet 1: 1

    CAS  Google Scholar 

  • Sirtori, C.R., Agradi, E., Conti, F., Mantero, O., and Gatti, E., 1977, Soybean-protein diet in the treatment of type-II hyperlipipoproteinaemia, Lancet 1: 275

    CAS  Google Scholar 

  • Story, J.A., and Kritchevsky, D., 1976, Comparison of the binding of various bile acids and bile salts in vitro by several types of fiber, J. Nutr 106: 1292

    CAS  Google Scholar 

  • Tasman Jones, C., 1980, Effects of dietary fiber on the structure and function of the small intestine, in: Medical Aspects of Dietary Fiber ( G.A. Spiller and R.M. Kay, eds.), pp. 67 – 74, Springer Science+Business Media New York

    Google Scholar 

  • Taylor, R.H., 1979, Gastric emptying, fibre, and absorption, Lancet 1: 872

    CAS  Google Scholar 

  • Thiffault, C., Belanger, M., and Pouliot, M., 1970, Traitment de l’hyperlipoproteinemie essentielle de type II par un nouvel agent therapeutique, la Celluline, Can. Med. Assoc. J 103: 165

    CAS  Google Scholar 

  • Thomson, A.B.R., and Dietschy, J.M., 1980, Experimental demonstration of the effect of unstirred water layer on the kinetic constants of the membrane transport of D-glucose in rabbit jejunum., J. Membr. Biol 54: 221

    CAS  Google Scholar 

  • Thornton, J.R., Emmett, P.M., and Heaton, K.W., 1979, Diet and Crohn’s disease: characteristics of the pre-illness diet, Br. Med. J 2: 762

    CAS  Google Scholar 

  • Topping, D.C., Trimble, R.P., Illman, R.J., Potter, J.D., and Oakenfull, D.G., 1980, Prevention of dietary hypercholesterolemia in the rat by soy flour high and low in saponins, Nutr. Rep. Int 22: 315

    Google Scholar 

  • Trowell, H.C., and Burkitt, D.P., 1975, Concluding considerations, in: Refined Carbohydrate Foods and Disease ( D.P. Burkitt and H.C. Trowell, eds.), pp. 333 – 345, Academic Press, London

    Google Scholar 

  • Truswell, A.S., and Kay, R.M., 1976, Bran and blood-lipids, Lancet 1: 367

    CAS  Google Scholar 

  • U.S. Senate Select Committee on Nutrition and Human Needs, Dietary Goals for The United States, U.S. Government Printing Office, Washington, D.C., 1977

    Google Scholar 

  • Vahouny, G.V., Tombes, R., Cassidy, M.M., Kritchevsky, D., and Gallo, L.L., 1980, Dietary fibers: V. Binding of bile salts, phospholipids and cholesterol from mixed micelles by bile sequestrants and dietary fibers, Lipids 15: 1012

    CAS  Google Scholar 

  • Van Itallie, T.B., Dietary fiber and obesity, 1978, Am. J. Clin. Nutr 31: S43

    Google Scholar 

  • Walton, R.J., Sherif, I.T., Noy, G.A., and Alberti, K.G.M.M., 1979, Improved metabolic profiles in insulin-treated diabetic patients given an alpha-glucosidehydrolase inhibitor, Br. Med. J 1: 220

    CAS  Google Scholar 

  • Werch, S.C., and Ivy, A.C., 1941, On the fate of ingested pectin, Am. J. Dig. Dis. 8:101. Williams, R.D., and Olmsted, W.H., 1936, The effect of cellulose, hemicellulose, and lignin on the weight of the stool: a contribution to the study of laxation in man, J. Nutr 11: 433

    Google Scholar 

  • Wynder, E.L., 1979, Dietary habits and cancer epidemiology, Cancer 43: 1955

    CAS  Google Scholar 

  • Wynder, E.L., 1979, Dietary habits and cancer epidemiology, Cancer 43: 1955

    CAS  Google Scholar 

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Jenkins, D.J.A., Jenkins, A.L. (1984). The Clinical Implications of Dietary Fiber. In: Draper, H.H. (eds) Advances in Nutritional Research. Advances in Nutritional Research, vol 110. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2801-8_7

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