Evidence for Alternative Pathways of Methionine Catabolism

  • N. J. Benevenga
Part of the Advances in Nutritional Research book series (ASIB, volume 110)


The catabolism of methionine has been reviewed most recently by Greenberg (1975b), Mudd and Levy (1978), and Finkelstein (1975). These reviews propose that the major route of methionine degradation is via the transsulfuration pathway (Fig. 1). Following activation of methionine to S-adenosylmethionine, the methionine methyl group is transferred to methyl acceptors such as glycine and phosphatidylethanolamine. The sulfur atom of methionine is recovered in homocysteine, cystathionine, and cysteine. Carbon atoms 1 through 4 are recovered in homocysteine, cystathionine, and α-ketobutyrate.


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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • N. J. Benevenga
    • 1
  1. 1.Departments of Meat Animal Science and Nutritional SciencesUniversity of WisconsinMadisonUSA

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