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Epidemiology and Population Monitoring in Genetic Risk Assessment

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Individual Susceptibility to Genotoxic Agents in the Human Population

Part of the book series: Environmental Science Research ((ESRH,volume 30))

Abstract

There are at the outset two quite separate approaches to genetic risk assessment and population monitoring that while often confused, must be carefully distinguished [1, 2, 3]. The first may be termed “surveillance”: the review and analysis of fluctuations in background rates of mutation inrarious populations to determine if there has been a mutagen introduced into the population or an increase in one already present. The second, to which the term “monitoring” may be applied and which is often of greater social concern is the evaluation over time of a population which has been exposed to a suspected or known mutagen. The process of monitoring thus addresses a specific problem, although the precise population at risk and the substances involved may or may not be known exactly. Because of the generality of the goals of surveillance — the review of background rates — it is possible to consider surveillance in a rather broad way and present an overview (see Ref. 2).

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Author information

Authors and Affiliations

  1. New York State Department of Health, Bureau of Maternal and Child Health, Albany, New York, 12237, USA

    Ernest B. Hook

  2. Department of Pediatrics, Albany Medical College, Albany, New York, 12208, USA

    Ernest B. Hook

Authors
  1. Ernest B. Hook
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Editor information

Editors and Affiliations

  1. Research Triangle Park, National Institute of Environmental Health Sciences, North Carolina, USA

    Frederick J. de Serres

  2. University of Lund, Lund, Sweden

    Ronald W. Pero

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© 1984 Plenum Press, New York

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Hook, E.B. (1984). Epidemiology and Population Monitoring in Genetic Risk Assessment. In: de Serres, F.J., Pero, R.W. (eds) Individual Susceptibility to Genotoxic Agents in the Human Population. Environmental Science Research, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2765-3_2

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  • DOI: https://doi.org/10.1007/978-1-4613-2765-3_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9709-3

  • Online ISBN: 978-1-4613-2765-3

  • eBook Packages: Springer Book Archive

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