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Aminoglycoside Nephrotoxicity — Clinical and Experimental Observations

  • Raymond D. Adelman
Chapter
Part of the Developments in Nephrology book series (DINE, volume 11)

Abstract

The aminoglycoside antibiotics are widely used in the pediatric age population for the treatment of serious gram negative infections. The incidence of nephrotoxicity in patients receiving aminoglycosides varies according to the criteria defining nephrotoxicity, the aminoglycoside used, and the presence or absence of risk factors. One proposed risk factor is sodium depletion. Although clinical information is largely anecdotal, substantial experimental data support the influence of sodium balance on aminoglycoside nephrotoxicity.

Keywords

Glomerular Filtration Rate Acute Renal Failure Plasma Creatinine Renin Angiotensin System Uranyl Nitrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1986

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  • Raymond D. Adelman

There are no affiliations available

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