Advertisement

Brief Communication Antibody Response to Epstein-Barr Virus-Specific DNase in Thirteen Patients with Nasopharyngeal Carcinoma

  • Jen-Yang Chen
  • R. Palmer Beasley
  • Chia-Siang Chien
  • Czau-Siung Yang
Part of the Developments in Medical Virology book series (DIMV, volume 1)

Abstract

Nasopharyngeal carcinoma (NPC) is one of the major neoplastic malignancies of Southern Chinese males. In Taiwan, it has been reported as the most common cancer of males (Yeh, 1966). A recent long-term study established that the survival rate over a 10-year period could be as high as 77% if the treatments were initiated at stage I of the disease (Hsu et al, 1981) and therefore an early diagnosis method is required.

Keywords

Nasopharyngeal Carcinoma Cellular Extract DNase Activity Geographic Aspect Juvenile Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. BEASLEY, R.P., HWANG, L.Y., LIN,C.C. and CHIEN,C.S. Hepatocellular carcinoma and hepatitis B virus: A prospective study of 22,707 men in Taiwan. Lancet 2, 1129–1133 (1981).PubMedCrossRefGoogle Scholar
  2. CHEN, J.Y., LIU, M.Y., LYNN, T.C. and YANG, C.S. Antibody to Epstein-Barr virus-specific DNase in patients with nasopharyngeal carcinoma. Chinese J. Microbiol. Immunol., 15, 255–261 (1982).Google Scholar
  3. CHENG, Y.C., CHEN, J.Y., HOFFMAN, P.J. and GLASER, R. Studies on the activity of DNase associated with the replication of Epstein-Barr virus. Virology, 100, 334–338 (1980a).PubMedCrossRefGoogle Scholar
  4. CHENG, Y.C., CHEN, J.Y., GLASER, R. and HENLE, W. Frequency and levels of antibodies to Epstein-Barr virus-specific DNase are elevated in patients with nasopharyngeal carcinoma. Proc. Natl. Acad. Sci. USA, 77, 6162–6165 (1980b).CrossRefGoogle Scholar
  5. CLOUGH, W, W. Deoxyribonuclease activity found in Epstein-Barr virus producing lymphoblastoid cells. Biochemistry, 18, 4517–4521 (1979).PubMedCrossRefGoogle Scholar
  6. HSU, M.M., LYNN, T.C., HSIEH, T., HUANG, S.C. and TU, S.M. Factors affecting the survival of patients with nasopharyngeal carcinoma, J. Formosan Med. Assoc., 80, 1296–1306 (1981).Google Scholar
  7. TAN, R.S., CHENG, Y.C., NAEGELE, R.F., HENLE, W., GLASER, R. and CHAMPION, J. Antibody responses to Epstein-Barr virus-specific DNase in relation to the prognosis of juvenile patients with nasopharyngeal carcinoma. Int. J. Cancer, 30, 561–565 (1982).PubMedCrossRefGoogle Scholar
  8. YEH, S. Some geographic aspects of most common diseases in Taiwan. Part two, Int. Pathol., 7, 24–28 (1966).Google Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1985

Authors and Affiliations

  • Jen-Yang Chen
    • 1
  • R. Palmer Beasley
    • 1
    • 2
  • Chia-Siang Chien
    • 3
  • Czau-Siung Yang
    • 1
  1. 1.Department of BacteriologyCollege of Medicine National Taiwan UniversityRepublic of China
  2. 2.University of Washington Medical Research UnitTaipeiRepublic of China
  3. 3.Government Employees’ Clinical CenterTaipei, TaiwanRepublic of China

Personalised recommendations