Summary
HLA typing of 76 low-risk patients with malignant tumors of the nasopharynx (n = 65) and histomorphologically identical carcinomas of the mesopharyngeal region (n = 11) showed no significantly different frequency of any HLA-antigen. A slight elevation of B-27 was shown for so-called lympholepithelial carcinomas of the nasopharyngeal region. Neither HLA Bw46 (Sin-2) nor any other NPC-linked antigen of high-risk groups has been found in our patients. Apparently, susceptibility to NPC in the Caucasian ethnic group is neither determined nor codetermined by class I antigens of the HLA system.
Keywords
- Nasopharyngeal Carcinoma
- Cancer Campaign
- Caucasian Ethnic Group
- Respiratory Tract Tumor
- Microlymphocytotoxicity Test
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1985 Martinus Nijhoff Publishing, Boston
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Bertram, G., Kruger, J., Sesterhenn, K. (1985). Brief Communication HLA-Antigens in NPC Patients from a Low — Risk Area (Cologne, FRG). In: Levine, P.H., Ablashi, D.V., Pearson, G.R., Kottaridis, S.D. (eds) Epstein-Barr Virus and Associated Diseases. Developments in Medical Virology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2625-0_19
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DOI: https://doi.org/10.1007/978-1-4613-2625-0_19
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