Monoclonal Antibodies in the Study of Cell Lineage, Differentiation and Malignancy in the Human Breast

  • J. Taylor-Papadimitriou
  • J. Bartek
  • E. Durban
  • J. Burchell
  • R. C. Hallowes
  • E. B. Lane
  • R. Millis
Part of the Developments in Oncology book series (DION, volume 35)


Monoclonal antibodies directed to cytokeratins, to surface mucins and to components exported by epithelial cells have been used to study cell lineages and differentiation phenotypes in the human mammary gland. These antibodies have been used to evaluate the suitability of in vitro culture systems for studying differentiation and to identify possible target cells in breast cancer. The practical application of the antibodies in cancer diagnosis and in the killing of tumour cells is discussed.


Lumenal Cell Human Mammary Gland Cell BioI Milk Cell Surface Mucin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Martinus Nijhoff Publishing, Boston 1985

Authors and Affiliations

  • J. Taylor-Papadimitriou
    • 1
  • J. Bartek
    • 2
  • E. Durban
    • 3
  • J. Burchell
    • 1
  • R. C. Hallowes
    • 1
  • E. B. Lane
    • 1
  • R. Millis
    • 1
  1. 1.Imperial Cancer Research FundLondonUK
  2. 2.Res. Institute of Clin. & Exp. OncologyBrnoCzechoslovakia
  3. 3.Baylor College of Med.HoustonUSA

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