Abstract
A study of immunohistochemical localization of estrogen receptor in one hundred and thirty-four human breast cancers and twenty-three metastatic lesions shows sensitivities and specificities of 91% as compared to biochemical analyses. A close correlation between the categorization of tumors by both methods is demonstrated. The immunohistochemical assay is shown to be sensitive and specific at threshold values of receptor. A comparison to clinical response for an initial cohort of twenty-three patients shows excellent predictive value for the immunohistochemical method.
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© 1985 Martinus Nijhoff Publishing, Boston
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McCarty, K., Snowhite, J., Cox, E., Miller, L., McCarty, K. (1985). Monoclonal Antibodies Against Estrogen Receptor: Specificity, Sensitivity and Potential Applications. In: Ceriani, R.L. (eds) Monoclonal Antibodies and Breast Cancer. Developments in Oncology, vol 35. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2617-5_14
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DOI: https://doi.org/10.1007/978-1-4613-2617-5_14
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