Skip to main content
SpringerLink
Log in

Clinical Disease and Its Economic Impact

  • Chapter
Marek’s Disease

Part of the book series: Developments in Veterinary Virology ((DVVI,volume 1))

Abstract

Marek’s disease (MD) is the most common clinical neoplastic condition of any animal, including man, on the globe. However, the clinical disease represents the “tip of the iceberg” in that many more birds are infected with the virus than show clinical signs. Clinical signs are also very varied.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Marek J: Multiple Nervenenzundung (polyneuritis) bei Hühnern. Dtsch Tieräerztl Wochenschr (15):417–421, 1907.

    Google Scholar 

  2. Benton WJ, Cover MS: The increased incidence of visceral lymphomatosis in broiler and replacement birds. Avian Dis (1):320–327, 1957.

    Article  Google Scholar 

  3. Biggs PM, Purchase HG, Bee BR, Dalton PJ: Preliminary report on acute Marek’s disease (fowl paralysis) in Great Britain. Vet Rec (77):1339–1340, 1965.

    Article  PubMed  CAS  Google Scholar 

  4. Purchase HG: Control of Marek’s disease by vaccination. World’s Poult Sci J (29):238–250, 1973.

    Article  Google Scholar 

  5. Eidson CS, Page RK, Kleven SB: Effectiveness of cell-free or cell-associated turkey herpesvirus vaccine against Marek’s disease in chickens as influenced by maternal antibody, and time of exposure to Marek’s disease virus. Avian Dis (22):583–597, 1978.

    Article  PubMed  CAS  Google Scholar 

  6. Witter RL, Sharma JM, Fadly AM: Pathogenicity of variant Marek’s disease isolants in vaccinated and unvaccinated chickens. Avian Dis (24):210–232, 1980.

    Article  Google Scholar 

  7. Schat KA, Calnek BW, Fabricant J: Influence of oncogenicity of Marek’s disease virus on evaluation of genetic resistance. Poult Sci (60):2559–2566, 1981.

    PubMed  CAS  Google Scholar 

  8. Biggs PM: The world of poultry disease. Avian Pathol (11):281–300, 1982.

    Google Scholar 

  9. FAO-WHO-OIE: Animal Health Yearbook 1979, FAO-WHO-OIE, Geneva/ Rome/Paris, 1980.

    Google Scholar 

  10. Lancaster JE: The zoo-sanitary situation in Africa. Avian Dis Rev Sci Tech Off Int Epiz (2):889–892, 1983.

    Google Scholar 

  11. Calnek BW, Witter RL: Marek’s disease. In: Hofstad MS, Calnek BW, Helmboldt CF, Reed WM, Yoder HW, Jr (eds). Diseases of Poultry, 7th ed. Iowa State University Press, Ames, Iowa, 1978, pp 385–418.

    Google Scholar 

  12. Kenzy SG, Cho BR: Transmission of classical Marek’s disease by affected and carrier birds. Avian Dis (13):211–214, 1969.

    Article  PubMed  CAS  Google Scholar 

  13. Powell PC, Howes K, Lawn AM, Mustill BM, Payne IN, Rennie M, Thompson MA: Marek’s disease in turkeys: The induction of lesions and the establishment of lymphoid cell lines. Avian Pathol (13):201–214, 1984.

    Article  PubMed  CAS  Google Scholar 

  14. Witter RL: Vaccines and vaccination against Marek’s disease. In: Proc Int Symp on Marek’s Disease. Ithaca, New York, July 22–26, 1984 (in press).

    Google Scholar 

  15. Kenzy SG, Cho BR, Kim Y: Oncogenic Marek’s disease herpes virus in avian encephalitis (temporary paralysis). J Natl Cancer Inst (51):977–982, 1973.

    PubMed  CAS  Google Scholar 

  16. Walker D, Grattan KAP: A temporary paralytic syndrome of growing pullets. Vet Rec (82):43–73, 1968.

    Google Scholar 

  17. Settnes OP: Marek’s disease: A common naturally herpesvirusinduced lymphoma of the chicken. Nord Vet Med Supp 11, 1982, pp. 132.

    Google Scholar 

  18. Fujita K, Uda K, Fukui H, Nishikawa K, Takei K, Okomura T: Outbreak of transient paralysis in broiler chickens. J Jpn Soc Poult Dis (17):167–171, 1981.

    Google Scholar 

  19. Purchase HG, Biggs PM: Characterization of five isolates of Marek’s disease. Res Vet Sci (8):440–449, 1967.

    PubMed  CAS  Google Scholar 

  20. Eidson CS, King DD, Connell HE, Anderson DP, Kleven SH: Efficacy of turkey herpesvirus vaccine against Marek’s disease in broilers. Poult Sci (52):1482–1491, 1973.

    PubMed  CAS  Google Scholar 

  21. Purchase HG: The etiology and control of Marek’s disease of chickens and the economic impact of a successful research program. In: Ranberger JA, Anderson JD, Powell RL (eds). Beltsville Symposia in Agricultural Research. I. Virology in Agriculture. Alanheld, Osmun & Co. Montclair, NJ, 1977, pp 63–81.

    Google Scholar 

  22. Honegger KA, McMurray BL, Gledhill RH, Purchase HG: Performance response of leghorn type layer flock to turkey herpesvirus vaccine. Avian Dis (16):78–85, 1972.

    Article  PubMed  CAS  Google Scholar 

  23. Kilgore RL: Prophylactic efficacy of a Marek’s disease vaccine in broiler and replacement layer chickens. Avian Dis (16):72–77, 1972.

    Article  PubMed  CAS  Google Scholar 

  24. Purchase HG, Okazaki W, Burmester BR: Long term field trials with the herpesvirus of turkeys vaccine against Marek’s disease. Avian Dis (16):34–44, 1972.

    Google Scholar 

  25. Biggs PM, Shilleto RFW, Lawn AM, Cooper DM: Idiopathic poly- neuritis in SPF chickens. Avian Pathol (11):163–178, 1982.

    Article  PubMed  CAS  Google Scholar 

  26. USDA, Code of Federal Regulations (CFR), Title 9, Chapter III, Subchapter C, part 381.76 and 381.82. 1982.

    Google Scholar 

  27. USDA, Food Safety and Inspection Service. Meat and Poultry Inspection, 1982. Report of the Secretary of Agriculture to the USA Congress, March 1, 1983. pp 51.

    Google Scholar 

  28. The Poultry Meat (Hygiene) Regulation. Statutory Instruments no. 1289. Food and Drugs, Food Hygiene. Her Majesty’s Stationery Office, London 1976.

    Google Scholar 

  29. The animals and animal products (control of export) law, 5717–1957 and the animal diseases ordinance, 1945. Regulations for the control of the manufacture of poultry products for export and their export. Ministry of Agriculture, Veterinary Services and Animal Health, Beit Dagan, Israel.

    Google Scholar 

  30. Republic of South Africa, Government Gazette. Regulation Gazette No. 1186. Vol. 52. No. 2540. 9th October 1969. pp. 83.

    Google Scholar 

  31. USDA, Agricultural Statistics. 1983. United States Government Printing Office, Washington, DC. 1983. pp 558.

    Google Scholar 

Download references

Authors
  1. H. G. Purchase
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Houghton Poultry Research Station, Houghton, Huntingdon, Cambs., PE17 2DA, UK

    L. N. Payne

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Martinus Nijhoff Publishing, Boston

About this chapter

Cite this chapter

Purchase, H.G. (1985). Clinical Disease and Its Economic Impact. In: Payne, L.N. (eds) Marek’s Disease. Developments in Veterinary Virology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2613-7_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2613-7_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9635-5

  • Online ISBN: 978-1-4613-2613-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation