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Genetic Resistance

  • Chapter
Marek’s Disease

Part of the book series: Developments in Veterinary Virology ((DVVI,volume 1))

Abstract

Genetically controlled differences in susceptibility to Marek’s disease (MD) were first reported over 50 years ago, when it was noted that the incidence of the disease differed amongst families (1–4). In 1935, Hutt and Cole (5) initiated their classic studies which were to prove that selection for genetic resistance could constitute a practical method for the control of disease in poultry flocks. Two resistant strains, K and C, and one susceptible strain, S, were developed by selection haled on mortality after natural exposure. Emphasis was on the avian leukosis complex and other neoplasms. Ultimately, marked differences were observed consistently in consecutive generations (6). This was accomplished without interference with concurrent and successful selection for important production traits (5). Other workers reported similar success in selection for resistance (7,8), and these early studies prompted some poultry breeders to develop their own resistant strains (9).

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Authors
  1. B. W. Calnek
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Editors and Affiliations

  1. Houghton Poultry Research Station, Houghton, Huntingdon, Cambs., PE17 2DA, UK

    L. N. Payne

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© 1985 Martinus Nijhoff Publishing, Boston

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Calnek, B.W. (1985). Genetic Resistance. In: Payne, L.N. (eds) Marek’s Disease. Developments in Veterinary Virology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2613-7_11

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  • DOI: https://doi.org/10.1007/978-1-4613-2613-7_11

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