Abstract
The purpose of this Chapter is to provide an introduction to the main studies and concepts concerning the nature and cause of Marek’s disease (MD) published between 1907, when the disease was first described by Marek (1), and the early 1960’s, when the transmissibility of MD was clearly established and rapid progress began to be made in its understanding. During this period there was great argument about the pathological nature and cause of MD, its relationship to other leukotic diseases, and its mode of natural transmission. The extensive literature published (see reviews 2–5) stands witness to this long debate and to the failure of the numerous studies to provide satisfactory answers to these questions. In retrospect, this was due to inadequate virological knowledge and techniques, lack of defined chickens for experimental reproduction of the disease, and inadequate facilities for properly controlled transmission studies.
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References
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© 1985 Martinus Nijhoff Publishing, Boston
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Payne, L.N. (1985). Historical Review. In: Payne, L.N. (eds) Marek’s Disease. Developments in Veterinary Virology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2613-7_1
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DOI: https://doi.org/10.1007/978-1-4613-2613-7_1
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