It is clear that the ST. JUDE MEDICAL® valve represents a significant design change, which has achieved improved hemodynamic function and, perhaps, decreased the incidence of thromboembolism after valve replacement. However, the hinge design for leaflet movement remains a major concern for long-term durability. There is less concern about the materials from which the valve is made; pyrolytic carbon has been in use long enough to show durability and biocompatibility.
KeywordsAspirin Coumadin Prothrombin Thromboxane Prostacyclin
Unable to display preview. Download preview PDF.
- 1.Horstkotte D, Haerten K, Seipel L, et al: Central hemodynamics at rest and during exercise after mitral valve replacement with different prostheses. Circulation 1983;68(suppl II):II-161—II-168.Google Scholar