Summary and Concluding Observations

  • Jack M. Matloff

Abstract

It is clear that the ST. JUDE MEDICAL® valve represents a significant design change, which has achieved improved hemodynamic function and, perhaps, decreased the incidence of thromboembolism after valve replacement. However, the hinge design for leaflet movement remains a major concern for long-term durability. There is less concern about the materials from which the valve is made; pyrolytic carbon has been in use long enough to show durability and biocompatibility.

Keywords

Aspirin Coumadin Prothrombin Thromboxane Prostacyclin 

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References

  1. 1.
    Horstkotte D, Haerten K, Seipel L, et al: Central hemodynamics at rest and during exercise after mitral valve replacement with different prostheses. Circulation 1983;68(suppl II):II-161—II-168.Google Scholar
  2. 2.
    Sullivan J, Harken D, Gorlin R. Pharmacologie control of thromboembolic complications of cardiac valve replacement. N Engl J Med 1971; 284 (25): 1086.CrossRefGoogle Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1985

Authors and Affiliations

  • Jack M. Matloff

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