Abstract
Nearly all higher eukaryotic cells have the capacity for active cell movement. Active movement occurs in a variety of normal biological processes and in several pathological conditions. Examples include fertilization, embryonic development, inflammation, wound healing and tumor cell invasion & metastasis. The involvement of cell motility in these complex biological processes insures that cell movement will not occur in an unregulated manner. Rather, the movement of cells in multicellular organisms in closely controlled. A number of different mechanisms appear to be involved. In addition to factors which turn cell movement “on” and “off”, there are factors which influence the direction in which cell movement occurs. Contact inhibition, contact guidance, haptotaxis and Chemotaxis are all terms that describe the regulation of directional cell movement.
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© 1985 Martinus Nijhoff Publishing, Boston
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Varani, J. (1985). Chemotaxis. In: Lands, W.E.M. (eds) Biochemistry of Arachidonic Acid Metabolism. Prostaglandins, Leukotrienes, and Cancer, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2597-0_14
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DOI: https://doi.org/10.1007/978-1-4613-2597-0_14
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