Abstract
It is only in recent years that factors defining the efficacy of antiarrhythmic drugs have been clearly defined. In patients with chronic potentially lethal ventricular arrhythmias without hemodynamical 1 y significant symptoms1 the most appropriate endpoint of drug efficacy should be the prevention of sudden cardiac death. The pharmacological endpoint of significant statistical reduction in ventricular ectopic frequency, however, has been the most widely applied “efficacy definition” to the study of new antiarrhythmic agents.
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© 1985 Martinus Nijhoff Publishing, Boston
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Morganroth, J. (1985). Role of Beta-Blocking Agents in the Treatment of Ventricular Arrhythmias. In: Morganroth, J., Moore, E.N. (eds) Cardiac Arrhythmias: New Therapeutic Drugs and Devices. Developments in Cardiovascular Medicine, vol 47. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2595-6_8
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DOI: https://doi.org/10.1007/978-1-4613-2595-6_8
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