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Effects of Trifluoperazine and Chlorpromazine on Calcium Paradox in Isolated Ventricle Strips

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 45))

Abstract

Uncontrolled calcium entry into the cell interior is an important feature in irreversible ischemic myocardium, reperfusion damage of ischemia (1, 2) and the myocardial damage associated with a large amount of catecholamine (3). It has been suggested that the calcium paradox phenomenon in the isolated perfused rat heart (4) is an appropriate model of typical myocardial cell injury caused by intracellular calcium overload.

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© 1985 Martinus Nijhoff Publishing, Boston

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Okumura, K., Ogawa, K., Satake, T. (1985). Effects of Trifluoperazine and Chlorpromazine on Calcium Paradox in Isolated Ventricle Strips. In: Beamish, R.E., Singal, P.K., Dhalla, N.S. (eds) Stress and Heart Disease. Developments in Cardiovascular Medicine, vol 45. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2587-1_19

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  • DOI: https://doi.org/10.1007/978-1-4613-2587-1_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9622-5

  • Online ISBN: 978-1-4613-2587-1

  • eBook Packages: Springer Book Archive

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