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Hyperleukocytosis in Adult Leukemia

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Book cover Chronic and Acute Leukemias in Adults

Part of the book series: Cancer Treatment and Research ((CTAR,volume 26))

Abstract

Patients with leukemia and hyperleukocytosis are at risk of developing leukostasis [1]. Patients with acute myeloid leukemia (AML) will tend to develop symptoms of leukostasis at a white blood count (WBC) of 100000/μl. Patients with chronic myelocytic leukemia (CML) will tend to develop symptoms of leukostasis at a higher WBC of over 200000/μL Patients with acute lymphocytic leukemia (ALL) and hyperleukocytosis have a poorer prognosis than patients with a lower WBC but leukostasis is not a common finding. Patients with chronic lymphocytic leukemia (CLL) very rarely develop symptoms from hyperleukocytosis unless the WBC is extremely elevated e.g. 400000/μl. Leukostasis was reported by us in a single patient with hairy cell leukemia and a WBC of 1 million/μl [2].

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Authors
  1. Janet Cuttner
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  2. Richard Meyer
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  3. Edward P. Ambinder
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  4. Tien-Nsi Young
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Editor information

Editors and Affiliations

  1. Section of Medical Oncology, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA

    Clara D. Bloomfield

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© 1985 Martinus Nijhoff Publishers, Boston

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Cuttner, J., Meyer, R., Ambinder, E.P., Young, TN. (1985). Hyperleukocytosis in Adult Leukemia. In: Bloomfield, C.D. (eds) Chronic and Acute Leukemias in Adults. Cancer Treatment and Research, vol 26. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2581-9_9

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  • DOI: https://doi.org/10.1007/978-1-4613-2581-9_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9619-5

  • Online ISBN: 978-1-4613-2581-9

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