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Chronic and Acute Leukemias in Adults pp 1–25Cite as

Retroviruses and Onc Genes in Human Leukemias and Lymphomas

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Part of the book series: Cancer Treatment and Research ((CTAR,volume 26))

Abstract

Retroviruses are of special importance in the understanding of the origin and pathogenesis of leukemias and lymphomas of man. Not only are they a major cause of naturally occurring leukemias and lymphomas in several animal species, thus providing useful model systems relating to the cause and development of neoplasias in man, but they also provide a means to identify and study some cellular genes (so-called onc genes) which are important in cell growth and differentiation and which have been transduced by the acutely transforming retroviruses. Many people believe that abnormal expression and/or qualitative modification of the c-onc genes are involved in the molecular pathogenesis of most or even all cancers no matter what the cause.

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Authors
  1. Eric H. Westin
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  2. Flossie Wong-Staal
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  3. Robert C. Gallo
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Editor information

Editors and Affiliations

  1. Section of Medical Oncology, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA

    Clara D. Bloomfield

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© 1985 Martinus Nijhoff Publishers, Boston

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Westin, E.H., Wong-Staal, F., Gallo, R.C. (1985). Retroviruses and Onc Genes in Human Leukemias and Lymphomas. In: Bloomfield, C.D. (eds) Chronic and Acute Leukemias in Adults. Cancer Treatment and Research, vol 26. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2581-9_1

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  • DOI: https://doi.org/10.1007/978-1-4613-2581-9_1

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