Skip to main content

Infections transmitted by blood transfusion

  • Chapter
Book cover Supportive therapy in haematology

Abstract

Infectious complications of blood transfusion [1] are twentieth century diseases which occur as adverse reactions to a twentieth century form of therapy, blood transfusion. Many of these infections are caused by historically well-established microorganisms; others are caused by agents of known diseases which have only been identified in recent decades; still others are caused by yet unidentified agents.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Reference

  1. Tabor E: Infectious complications of blood transfusion. Academic Press, New York, 1982.

    Google Scholar 

  2. Alter HJ, Holland PV, Purcell RH: The emerging pattern of post-transfusion hepatitis. Am J Med Sci, 1975; 270: 329–34.

    Article  PubMed  CAS  Google Scholar 

  3. Aach RD, Lander JJ, Sherman LA, Miller WV, Kahn RA, Gitnick GL, Hollinger FB, Werch J, Szmuness W, Stevens CE, Kellner A, Weiner JM, Mosley J W: Transfusion-transmitted viruses: interim analysis of hepatitis among transfused and nontransfused patients. In: Viral Hepatitis, Vyas GN, Cohen SN, Schmid R (eds). Franklin Inst. Press, Philadelphia, 1978: 383–96.

    Google Scholar 

  4. Alter HI, Purcell RH, Holland PV, Feinstone SM, Morrow AG, Moritsugu Y: Clinical and serological analysis of transfusion-associated hepatitis. Lancet, 1975; ii: 838–41.

    Article  Google Scholar 

  5. Tabor E: The three viruses of non-A, non-B hepatitis. Lancet, 1985; i: 743–45.

    Article  Google Scholar 

  6. Heimburger N, Schwinn H, Gratz P, Luben G, Kumpe G, Herchenhan B: Factor VIII concentrate, highly purified and heated in solution. Arzneim Forsch, 1981; 31: 619–22.

    CAS  Google Scholar 

  7. Heimburger N, Schwinn H, Mauler R: Factor VIII concentrate, hepatitis-safe: progress in the treatment of hemophilia A. Die Gelben Hefte, 1980; 20: 165–74.

    Google Scholar 

  8. Hollinger FB, Dolana G, Thomas W, Gyorkey F, Kingdon H: Heat-inactivation of a non-A, non-B hepatitis agent and hepatitis B virus in human clotting factor concentrates. Hepatology, 1982; 2: 705 (abstract).

    Google Scholar 

  9. Tabor E, Aronson DL, Gerety RJ: Removal of hepatitisB-virus infectivity from factor-IX complex by hepatitis-B immune-globulin. Lancet, 1980; 2: 68–70.

    Article  PubMed  CAS  Google Scholar 

  10. Knodell RG, Conrad ME, Ginsberg AL, Bell CJ, Flannery EP: Efficacy of prophylactic gamma-globulin in preventing non-A, non-B post-transfusion hepatitis. Lancet, 1976; i: 557–61.

    Article  Google Scholar 

  11. Seeff LB, Wright EC, Zimmerman HJ, Hoofnagle JH, Dietz AA, Felsher BF, Garcia-Pont PH, Gerety RJ, Greenlee HB, Kiernan T, Leevy CM, Nath N, Schiff ER, Schwartz C, Tabor E, Tamburro C, Vlahcevic Z, Zemel R, Zimmon DS: Posttransfusion hepatitis, 1973–1975: a Veterans Administration cooperative study. In: Viral Hepatitis, Vyas GN, Cohen SN, Schmid R (eds). Franklin Inst. Press, Philadelphia, 1978: 371–81.

    Google Scholar 

  12. Szmuness W, Stevens CE, Harley EJ, Zang EA, Oleszko WR, William DC, Sadovsky R, Morrison JM, Kellner A: Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high-risk population in the United States. N Engl J Med, 1980; 303: 833–41.

    Article  PubMed  CAS  Google Scholar 

  13. Crosnier J, Jungers P, Couroucé AM, Laplanche A, Benhamou E, Degos F, Lacour B, Prunet P, Cerisier Y, Guesry P: Randomised placebo-controlled trial of hepatitis B surface antigen vaccine in French haemodialysis units: I, Medical staff. Lancet, 1981; i: 455–59.

    Article  Google Scholar 

  14. Lerner RA, Green N, Alexander H, Liu FT, Sutcliffe JG, Shinnick TM: Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus gen-orne elicit antibodies reactive with the native envelope protein of Dane particles. Proc Natl Acad Sci USA, 1981; 78: 3403–7.

    Article  PubMed  CAS  Google Scholar 

  15. Valenzuela P, Medina A, Rutter WJ: Synthesis and assembly of hepatitis B virus surface antigen particles in yeast. Nature, 1982; 298: 347–50.

    Article  PubMed  CAS  Google Scholar 

  16. Havens WP: Period of infectivity of patients with experimentally induced infectious hepatitis. J Exp Med, 1946; 83: 251–58.

    Article  CAS  Google Scholar 

  17. Seeberg S, Brandberg A, Hermodsson S, Larsson P, Lundgren S: Hospital outbreak of hepatitis A secondary to blood exchange in a baby. Lancet, 1981; i: 1155–56.

    Article  Google Scholar 

  18. Skidmore SJ, Boxall EH, Ala F: A case report of post-transfusion hepatitis A. J Med Virol, 1982; 10: 223.

    Article  PubMed  CAS  Google Scholar 

  19. Barbara JAJ, Howell DR, Briggs M, Parry JV: Post-transfusion hepatitis A. Lancet, 1982; i: 738 (letter).

    Article  Google Scholar 

  20. Alter HJ, Purcell RH, Holland PV, Feinstone SM, Morrow AG, Moritsugu Y: Clinical and serological analysis of transfusion-associated hepatitis. Lancet, 1975; ii: 838–41.

    Article  Google Scholar 

  21. Dienstag JL, Alaama A, Mosley JW, Redecker AG, Purcell RH: Etiology of sporadic hepatitis B surface antigen-negative hepatitis. Ann Intern Med, 1977; 87: 1–6.

    PubMed  CAS  Google Scholar 

  22. Berman M, Alter HJ, Ishak KG, Purcell RH, Jones EA: The chronic sequelae of non-A, non-B hepatitis. Ann Intern Med, 1979; 91: 1–6.

    PubMed  CAS  Google Scholar 

  23. Norkrans G, Frösner G, Hermodsson S, Iwarson S: Clinical, epidemiological and prognostic aspects of hepatitis ‘non-A, non-B’ - a comparison with hepatitis A and B. Scand J Infect Dis, 1979; 11: 259–64.

    PubMed  CAS  Google Scholar 

  24. Tabor E, Seeff LB, Gerety RJ: Chronic non-A, non-B hepatitis carrier state: transmissible agent documented in one patient over a six-year period. N Engl J Med, 1980; 303: 139–43.

    Article  Google Scholar 

  25. Tabor E, Gerety RJ: The chimpanzee animal model for non-A, non-B hepatitis: new applications. In: Viral Hepatitis: 1981 International Symposium, W Szmuness, HJ Alter, JE Maynard (eds). Franklin Inst Press, Philadelphia, 1982: 305–17.

    Google Scholar 

  26. Seeff LB, Zimmerman HJ, Wright EC, Finkelstein JD, Garcia-Pont P, Greenlee HB, Dietz AA, Leevy CM, Tamburro CH, Schiff ER, Schimmel EM, Zemel R, Zimmon DS, McCollum RW: A randomized, double-blind controlled trial of the efficacy of immune serum globulin for the prevention of post-transfusion hepatitis. Gastroenterology, 1977; 72: 111–21.

    PubMed  CAS  Google Scholar 

  27. Knodell RG, Conrad ME, Ishak KG: Development of chronic liver disease after acute non-A, non-B post-transfusion hepatitis: role of gamma-globulin prophylaxis in its prevention. Gastroenterology, 1977; 72: 902–9.

    PubMed  CAS  Google Scholar 

  28. Tabor E, Gerety RJ: Inactivation of an agent of human non-A, non-B hepatitis by formalin. J Infect Dis, 1980; 142: 767–70.

    Article  PubMed  CAS  Google Scholar 

  29. Yoshizawa H, Itoh Y, Iwakiri S, Kitajima K, Tanaka A, Tachibana T, Nakamura T, Miyakawa Y, Mayumi M: Non-A, non-B (type 1) hepatitis agent capable of inducing tubular ultrastructures in the hepatocyte cytoplasm of chimpanzees: inactivation by formalin and heat. Gastroenterology, 1982; 82: 502–6.

    PubMed  CAS  Google Scholar 

  30. Aach RD, Szmuness W, Mosley JW, Hollinger FB, Kahn, RA, Stevens CE, Edwards VM, Werch J: Serum alanine aminotransferase of donors in relation to the risk of non-A, non-B hepatitis in recipients: the Transfusion-Transmitted Viruses Study. N Engl J Med, 1981; 304: 989–94.

    Article  PubMed  CAS  Google Scholar 

  31. Holland PV, Bancroft W, Zimmerman H: Post-transfusion viral hepatitis and the TTVS. N Engl J Med, 1981; 304: 1033–34.

    Article  PubMed  CAS  Google Scholar 

  32. Tabor E, Hoofnagle JH, Smallwood LA, Drucker JA, Pineda-Tamondong GC, Ni LY, Greenwalt TJ, Barker LF, Gerety RJ: Studies of donors who transmit posttransfusion hepatitis. Transfusion, 1979; 19: 725–31.

    Article  PubMed  CAS  Google Scholar 

  33. Kreel I, Zoroff LI, Cantes JW, Krasna I, Baronofsky ID: A syndrome following total body perfusion. Surg Gynecol Obstet, 1960; 111: 317–21.

    PubMed  CAS  Google Scholar 

  34. Prince AM, Szmuness W, Millian SJ, David DS: A serological study of cytomegalovirus infections associated with blood transfusions. N Engl J Med, 1971; 284: 1125–31.

    Article  PubMed  CAS  Google Scholar 

  35. Enck RE, Betts RF, Brown MR, Miller G: Viral serology (hepatitis B virus, cytomegalovirus, Epstein-Barr virus) and abnormal liver function tests in transfused patients with hereditary hemorrhagic diseases. Transfusion, 1979; 19: 32–38.

    Article  PubMed  CAS  Google Scholar 

  36. FDA. AIDS update. FDA Drug Bulletin, 1983; 13: 9–11.

    Google Scholar 

  37. Tolkoff-Rubin NE, Rubin RH, Keller EE, Baher GP, Stewart JA, Hirsch MS: Cytomegalovirus infection in dialysis patients and personnel. Ann Intern Med, 1978; 89: 625–28.

    PubMed  CAS  Google Scholar 

  38. Yeager AS, Grumet FC, Hafleigh EB, Arvin AM, Bradley JS, Prober CG: Prevention of transfusion-acquired cytomegalovirus infections in newborn infants. J Pediatr, 1981; 98: 281–87.

    Article  PubMed  CAS  Google Scholar 

  39. Winston DJ, Ho WG, Howell CL, Miller MJ, Mickey R, Martin WJ, Lin CH, Gale RP: Cytomegalovirus infections associated with leukocyte transfusions. Ann Intern Med, 1980; 93: 671–75.

    PubMed  CAS  Google Scholar 

  40. Gerber P, Walsh JH, Rosenblum EN, Purcell RH: Association of EB-virus infection with the post-perfusion syndrome. Lancet, 1969; i: 593–96.

    Article  Google Scholar 

  41. Henle W, Henle G, Scriba M, Joyner CR, Harrison RS, von Essen R, Paloheimo J, Klemola E: Antibody responses to the Epstein-Barr virus and cytomegaloviruses after open-heart and other surgery. N Engl J Med, 1970; 282: 1068–74.

    Article  PubMed  CAS  Google Scholar 

  42. Goetz O, Peller P, Weick B: Epstein-Barr virus antibodies after blood transfusion. Dtsch Med Wochenschr, 1974; 99: 448–50.

    Article  PubMed  CAS  Google Scholar 

  43. Rocchi G, de Felici A, Ragona G, Heinz A: Quantitative evaluation of Epstein-Barr-virus-infected mononuclear peripheral blood leukocytes in infectious mononucleosis. N Engl J Med, 1977; 296: 132–34.

    Article  PubMed  CAS  Google Scholar 

  44. Solem JH, Jorgensen W: Accidentally transmitted infectious mononucleosis: report of a case. Acta Med Scand, 1969; 186: 433–37.

    Article  PubMed  CAS  Google Scholar 

  45. Turner RA, MacDonald RN, Cooper BA: Transmission of infectious mononucleosis by transfusion of pre-illness plasma. Ann Intern Med, 1972; 77: 751–53.

    PubMed  CAS  Google Scholar 

  46. Evans AS: Further experimental attempts to transmit infectious mononucleosis to man. J Clin Invest, 1950; 29: 508–12.

    Article  PubMed  CAS  Google Scholar 

  47. Rizzetto M, Purcell RH, Gerin JL: Epidemiology of HBV-associated delta agent: geographical distribution of anti-delta and prevalence in polytransfused HBsAg carriers. Lancet, 1980; i: 1215–19.

    Article  Google Scholar 

  48. Morgan HJ: Factors conditioning the transmission of syphilis by blood transfusion. Am J Med Sei, 1935; 189: 808–13.

    Article  Google Scholar 

  49. Klauder JV, Butterworth T: Accidental transmission of syphilis by blood transfusion. Am J Syph, Gonorrhea, Vener Dis, 1937; 21: 652–66.

    Google Scholar 

  50. Turner TB, Diseker TH: Duration of infectivity of Treponema pallidum in citrated blood stored under conditions obtaining in blood banks. Bull Johns Hopkins Hosp, 1941; 68: 269–79.

    Google Scholar 

  51. Kolmer JA: A note on the survival of Treponema pallidum in preserved citrated human blood and plasma. Am J Syph, Gonorrhea, Vener Dis, 1942; 26: 156–58.

    Google Scholar 

  52. Guthrie N: Failure of stored syphilitic blood to transmit syphilis: a case report. J Vener Dis Inf, 1951; 32: 246–47.

    PubMed  CAS  Google Scholar 

  53. Walker RH: The disposition of STS reactive blood in a transfusion service. Transfusion, 1965; 5: 452–56.

    Article  PubMed  CAS  Google Scholar 

  54. Spangler AS, Jackson JH, Fiumara NJ, Warthin TA: Syphilis with a negative blood test reaction. J Am Med Assoc, 1964; 189: 87–90.

    CAS  Google Scholar 

  55. Bruce-Chwatt LJ: Blood transfusion and tropical disease. Trop Dis Bull, 1972; 69: 825–62.

    PubMed  CAS  Google Scholar 

  56. Fajardo LF: The role of platelets in infections: I. Observations in human and murine malaria. Arch Pathol Lab Med, 1979; 103: 131–34.

    PubMed  CAS  Google Scholar 

  57. Lozner EL, Newhouser LR: Studies on the transmissibility of malaria by plasma transfusions. Am J Med Sei, 1943; 206: 141–46.

    Article  Google Scholar 

  58. Miller LH: Transfusion malaria. In: Transmissible Disease and Blood Transfusion, TJ Greenwalt, GA Jamieson (eds) Grune and Stratton, New York, 1975: 241–66.

    Google Scholar 

  59. Knott J: The periodicity of the microfilaria of Wuchereria bancrofti. Trans R Soc Trop Med Hyg, 1935; 29: 59–64

    Article  Google Scholar 

  60. Salazar HJ, Arends T, Maekelt GA: Documentation in Venezuela of the transmission of Trypanosoma cruzi by blood transfusion. Arch Venez Med Trop Parasitol Med, 1962; 4: 355–63.

    Google Scholar 

  61. Undiano C: Posttransfusion Chagas’ disease. Rev Fac Cienc Med Cordoba, 1969; 27: 143–46.

    PubMed  CAS  Google Scholar 

  62. Coura JR, Nogueira ES, da Silva JR: Indices of transmission of Chagas’ disease by blood transfusion from donors in the chronic phase of the disease. Hospital (Rio de Janeiro), 1966; 69: 991–98.

    CAS  Google Scholar 

  63. Cerisola JA, Rabinovich A, Alvarez M, DiCorleto CA, Pruneda J: Chagas’ disease and blood transfusion. Bol Of Sanit Panam, 1972; 73: 203–21.

    CAS  Google Scholar 

  64. Jacoby GA, Hunt JV, Kosinski KS, Demirjian ZN, Huggins C, Etkind P, Marcus LC, Spielman A: Treatment of transfusion-transmitted babesiosis by exchange transfusion. N Engl J Med, 1980; 303: 1098–1100.

    Article  PubMed  CAS  Google Scholar 

  65. Jaffe HW, Bregman DJ, Selik RM: Acquired immune deficiency syndrome in the United States: the first 1,000 cases. J Infect Dis, 1983; 148: 339–45.

    Article  PubMed  CAS  Google Scholar 

  66. Ammann AJ, Cowan MJ, Wara DW, Weintrub P, Dritz S, Goldman H, Perkins HA: Acquired immunodeficiency in an infant: possible transmission by means of blood products. Lancet, 1983; i: 956–58.

    Article  Google Scholar 

  67. Gury DJ: AIDS and the paid donor. Lancet, 1983; ii: 575.

    Article  Google Scholar 

  68. Centers for Disease Control. Prevention of acquired immune deficiency syndrome (AIDS): report of inter-agency recommendations. Morbid Mortal Week Rep, 1983; 32: 101–3.

    Google Scholar 

  69. Mortimer PP, Luban NLC, Kelleher JF, Cohen BJ: Transmission of serum parvovirus-like virus by clotting-factor concentrates. Lancet, 1983; ii: 482–84.

    Article  Google Scholar 

  70. Cossart YE, Field AM, Cant B, Widdows D: Parvoviruslike particles in human sera. Lancet, 1975; i: 72–73.

    Article  Google Scholar 

  71. Anderson MJ: The emerging story of a human parvoviruslike agent. J Hyg Camb, 1982; 89: 1–8.

    Article  PubMed  CAS  Google Scholar 

  72. Evatt BL, Stein SF, Francis DP, Lawrence DN, McLane MF, McDougal JS, Lee TH, Spira TJ, Cabradilla C, Mullens JI, Essex M: Antibodies to human T cell leukaemia virus-associated membrane antigens in haemophiliacs: evidence for infection before 1980. Lancet, 1983; ii: 698–701.

    Article  Google Scholar 

  73. Gallo RC, Wong-Staal F: Retroviruses as etiologic agents of some animal and human leukemias and lymphomas and as tools for elucidating the molecular mechanism of leukemogenesis. Blood, 1982; 60: 545–57.

    PubMed  CAS  Google Scholar 

  74. Hinuma Y, Komoda H, Chosa T, Kondo T, Kohakura M, Takenaka T, Kikuchi M, Ichimaru M, Yunoki K, Sato I, Matsuo R, Takiuchi Y, Uchino H, Hanaoka M: Antibodies to adult T-cell leukemia-virus-associated antigen (ATLA) in sera from patients with ATL and controls in Japan: a nation-wide sero-epidemiologic study. Int J Cancer, 1982; 29: 631–35.

    Article  PubMed  CAS  Google Scholar 

  75. Blayney DW, Blattner WA, Robert-Guroff M, Jaffe ES, Fisher RI, Bunn PA, Patton MG, Rariek HR, Gallo RC: The human T-cell leukemia-lymphoma virus in the Southeastern United States. J Am Med Assoc, 1983; 250: 104852.

    Google Scholar 

  76. Miyoshi I, Taguchi H, Fujishita M, Niiya K, Kitagawa T, Ohtsuki Y, Akagi T: Asymptomatic type C virus carriers in the family of an adult T-cell leukemia patient. Gann, 1982; 73: 339–40.

    PubMed  CAS  Google Scholar 

  77. Editorial: Blood transfusion, haemophilia, and AIDS. Lancet, 1984, ii: 1433–35.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Martinus Nijhoff Publishers. Boston/Dordrecht/Lancaster

About this chapter

Cite this chapter

Tabor, E. (1985). Infections transmitted by blood transfusion. In: Das, P.C., Sibinga, C.T.S., Halie, M.R. (eds) Supportive therapy in haematology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2577-2_30

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2577-2_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9617-1

  • Online ISBN: 978-1-4613-2577-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics