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Role of cell culture in the management of haematological diseases

  • Chapter
Supportive therapy in haematology

Abstract

Morphological examination of the bone marrow allows analysis of cells at the level of the terminal five or six divisions in the differentiation pathway. A greater number of divisions have already occurred, however, between the haematopoietic stem cells and the earliest recognizable precursors, and it is at this level that many haematological disorders arise. These cells involved in the early stages of differentiation are clearly too few to be examined microscopically and the enumeration of these cells and the study of their regulation is dependent upon in vitro clonal assays.

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    P. C. Das  & C. Th. Smit Sibinga  & 

  2. Dept. of Haematology, University Hospital, Groningen, The Netherlands

    M. R. Halie

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Linch, D.C. (1985). Role of cell culture in the management of haematological diseases. In: Das, P.C., Sibinga, C.T.S., Halie, M.R. (eds) Supportive therapy in haematology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2577-2_1

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