Skip to main content

Staging and second-look operations in ovarian cancer

  • Chapter

Part of the book series: Cancer Treatment and Research ((CTAR,volume 23))

Abstract

The appropriate management of patients with ovarian cancer requires a thorough primary surgical staging, and a subsequent surgical evaluation of response to therapy is often indicated. In most patients, even those whose tumors have disseminated throughout the peritoneal cavity, the extent of disease prior to initiation of therapy is unclear because the metastases are asymptomatic. In addition, since the majority of individuals are in clinical remission at the completion of their chemotherapy, an operative method is needed to assess the response to therapy, because noninvasive techniques are too insensitive. The ‘second-look’ operation has become a standard procedure in many institutions.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Day TG, Smith JP: Diagnosis and staging of ovarian cancer. Semin Oncol 2:217, 1975.

    PubMed  Google Scholar 

  2. Scully RE: Tumors of the ovary and maldeveloped gonads. AFIP Fascicle 16, Washington D.C., 1979.

    Google Scholar 

  3. Plentl AA, Friedman EA: Lymphatic system of the female genitalia. W.B. Saunders Co., Philadelphia, 1971.

    Google Scholar 

  4. Fisher R, Young R: Advances in the staging and treatment of ovarian cancer. Cancer 39:967, 1977.

    Article  PubMed  CAS  Google Scholar 

  5. Hreschchyshyn MM, Park RC, Blessing JA, Norris HJ, Levy D, Lagasse LD, Creasman WT: The role of adjuvant therapy in Stage I ovarian cancer. Am J Obstet Gynecol 138:139, 1980.

    Google Scholar 

  6. Piver MS, Barlow JJ, Lele SB: Incidence of subclinical metastasis in Stage I and II ovarian carcinoma. Obstet Gynecol 52:100, 1978.

    PubMed  CAS  Google Scholar 

  7. Creasman WT, Rutledge F: The prognostic value of peritoneal cytology in gynecologic malignant disease. Am J Obstet Gynecol 110:773, 1971.

    PubMed  CAS  Google Scholar 

  8. Keettel WC, Pixley EE, Buchsbaum HJ: Experience with peritoneal cytology in the management of gynecologic malignancies. Am J Obstet Gynecol 120:174, 1974.

    PubMed  CAS  Google Scholar 

  9. Delgado G, Chun B, Caglar H: Paraaortic lymphadenectomy in gynecologic malignancies confined to the pelvis. Obstet Gynecol 50:418, 1977.

    PubMed  CAS  Google Scholar 

  10. Morton DG, Moore JG, Chang N: The clinical value of peritoneal lavage for cytologic evaluation. Am J Obstet Gynecol 81:1115, 1961.

    PubMed  CAS  Google Scholar 

  11. Buchsbaum H, Delgado G, Miller A: Surgical staging of ovarian cancer. Gynecologic Oncology Group: Statistical Report. Denver, CO, July 1983, pp 27–28.

    Google Scholar 

  12. Knapp RC, Friedman EA: Aortic lymph node metastases in early ovarian cancer. Am J Obstet Gynecol 119:1013–1017, 1974.

    PubMed  CAS  Google Scholar 

  13. Rosenoff SH, DeVita VT Jr, Hubbard S, et al.: Peritoneoscopy in the staging and followup of ovarian cancer. Semin Oncol 2:223, 1975.

    PubMed  CAS  Google Scholar 

  14. Musumeci R, DePalo G, Kenda R. et al.: Retroperitoneal metastases from ovarian carcinoma: Reasessment of 365 patients studied with lymphography. Am J Radiol 134:449–452, 1980.

    CAS  Google Scholar 

  15. Berek JS, Hacker NF: Laparoscopy in the management of patients with ovarian carcinoma, in The Treatment of Ovarian Cancer, edited by DiSaia P, Chapter 4, W.B. Saunders, london, August, 10(2):213–222, 1983.

    Google Scholar 

  16. Bagley CM, Young RC, Schien PS, Chabner BA, DeVita VT: Ovarian cancer metastatic to the diaphragm frequently undiagnosed at laparotomy. A preliminary report. Am J Obstet Gynecol 116:397–404, 1973.

    PubMed  Google Scholar 

  17. Rosenoff SH, Young RC, Anderson T, et al.: Peritoneoscopy: a valuable staging tool in ovarian carcinoma. Ann Int Med 83:37–41, 1975.

    PubMed  CAS  Google Scholar 

  18. Spinelli P, Luini A, Pizzetti P, DePalo GM: Laparoscopy in staging and restaging of 95 patients with ovarian carcinoma. Tumori 62:493–502, 1976.

    PubMed  CAS  Google Scholar 

  19. Piver MS, Lopez RG, Xynos F, et al.: The value of pre-therapy peritoneoscopy in localized ovarian cancer. Am J Obstet Gynecol 127:288, 1977.

    PubMed  CAS  Google Scholar 

  20. Mangioni C, Bolis G, Molteni P, Belloni C: Indications, advantages and limitations of laparoscopy in ovarian cancer. Gyn Oncol 7:47–55, 1979.

    Article  CAS  Google Scholar 

  21. Ozols RF, Fisher RI, Anderson T, Makuch R, Young RC: Peritoneoscopy in the management of ovarian cancer. Am J obstet Gynecol 140:611–619, 1981.

    PubMed  CAS  Google Scholar 

  22. Berek JS, Griffiths CT, Leventhal JM: Laparoscopy of second-look evaluation in ovarian cancer. Obstet Gynecol 58:192–198, 1981.

    PubMed  CAS  Google Scholar 

  23. Hassan HM: A modified instrument and method for laparoscopy. Am J Obstet Gynecol 110:886–889, 1971.

    Google Scholar 

  24. Griffiths CT: Surgical resection of tumor bulk in the primary treatment of ovarian carcinoma. Natl CA Institute Monograph 42:101–104, 1975.

    CAS  Google Scholar 

  25. Griffiths CT, Fuller AF: Intensive surgical management of advanced ovarian cancer. Surg Clinic No Amer 58:131–143, 1978.

    CAS  Google Scholar 

  26. Hacker NF, Berek JS, Lagasse LD, et al.: Primary cytoreductive surgery in ovarian cancer. Obstet Gynecol 61:413–420, 1983.

    PubMed  CAS  Google Scholar 

  27. Schwartz PE, Smith JP: Second-look operation in ovarian cancer. Am J Obstet Gynecol 138:1124, 1980.

    PubMed  CAS  Google Scholar 

  28. Smith JP, Delgado G, Rutledge F: Second-look operation in ovarian cancer. Cancer 38:1438, 1976.

    Article  PubMed  CAS  Google Scholar 

  29. Phillips BD, Buchsbaum HJ, Lifshitz S: Re-exploration after treatment for ovarian carcinoma. Gynecol Oncol 8:339, 1979.

    Article  PubMed  CAS  Google Scholar 

  30. Curry SL, Zembo MM, Nahhas WA, et al.: Second-look laparotomy for ovarian cancer. Gynecol Oncol 11:114, 1981.

    Article  PubMed  CAS  Google Scholar 

  31. Webb MJ, Snyder JA, Williams TJ, et al.: Second-look laparotomy in ovarian cancer. Gynecol Oncol 14:285, 1982.

    Article  PubMed  CAS  Google Scholar 

  32. Raju KS, McKinna JA, Barker GH, et al.: Second-look operations in the planned management of advanced ovarian carcinoma. Am J Obstet Gynecol 144:650, 1982.

    PubMed  CAS  Google Scholar 

  33. Roberts WS, Hodel K, Rich WM, et al.: Second-look laparotomy in the management of gynecologic malignancy. Gynecol Oncol 13:345, 1982.

    Article  PubMed  CAS  Google Scholar 

  34. Gershenson DM, Copeland CJ, Wharton JT, et al.: Surgically-determined complete responders in advanced ovarian cancer. Proc Soc Gyn Onc 14:18, Marco Island, FL, 1983.

    Google Scholar 

  35. Berek JS, Hacker NF, Lagasse LD, et al.: Second-look laparotomy in Stage III epithelial ovarian cancer: clinical variables associated with disease status. Obstet Gynecol 64:207–212, 1984.

    PubMed  CAS  Google Scholar 

  36. Berek JS, Hacker NF, Lagasse LD, et al.: Survival of patients with ovarian cancer following secondary cytoreductive surgery. Obstet Gynecol 61:189–193, 1983.

    PubMed  CAS  Google Scholar 

  37. Young RC, Chabner BA, Hubbard SP, et al.: Advanced ovarian adenocarcinoma: a prospective clinical trial of melphalan (L-PAM) versus combination chemotherapy. N Engl J Med 299:1261, 1978.

    Article  PubMed  CAS  Google Scholar 

  38. Kapadia SB, Krause JR: Ovarian carcinoma terminating in acute nonlymphocytic leukemia following alkylating agent therapy. Cancer 41:1670–1680, 1978.

    Article  Google Scholar 

  39. Reimer RA, Hoover R, Fraumeni JF, Young RC: Acute leukemia alkylating agent therapy of ovarian cancer. N Eng J Med 297:177–181, 1977.

    Article  CAS  Google Scholar 

  40. Piver MS, Lele SB, Barlow JJ, Gamarra M: Second-look laparoscopy prior to proposed second-look laparotomy. Obstet Gynecol 55:571–573, 1980.

    PubMed  CAS  Google Scholar 

  41. Lacey CG, Morrow CP, DiSaia PJ, Lucas WE: Laparoscopy in the evaluation of gynecologic cancer. Obstet Gynecol 52:708–712, 1978.

    PubMed  CAS  Google Scholar 

  42. Smith WG, Day TG, Smith JP: The use of laparoscopy to determine the results of chemotherapy for ovarian cancer. J Rep Med 18:257–260, 1977.

    CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Martinus Nijhoff Publishers, Boston

About this chapter

Cite this chapter

Berek, J.S., Hacker, N.F. (1985). Staging and second-look operations in ovarian cancer. In: Alberts, D.S., Surwit, E.A. (eds) Ovarian Cancer. Cancer Treatment and Research, vol 23. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2561-1_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2561-1_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9609-6

  • Online ISBN: 978-1-4613-2561-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics